BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 25126724)

  • 1. MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia.
    Zeng CW; Chen ZH; Zhang XJ; Han BW; Lin KY; Li XJ; Wei PP; Zhang H; Li Y; Chen YQ
    Autophagy; 2014 Oct; 10(10):1726-37. PubMed ID: 25126724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.
    Chen ZH; Wang WT; Huang W; Fang K; Sun YM; Liu SR; Luo XQ; Chen YQ
    Cell Death Differ; 2017 Feb; 24(2):212-224. PubMed ID: 27740626
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein.
    Isakson P; Bjørås M; Bøe SO; Simonsen A
    Blood; 2010 Sep; 116(13):2324-31. PubMed ID: 20574048
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation.
    Nasr R; Guillemin MC; Ferhi O; Soilihi H; Peres L; Berthier C; Rousselot P; Robledo-Sarmiento M; Lallemand-Breitenbach V; Gourmel B; Vitoux D; Pandolfi PP; Rochette-Egly C; Zhu J; de Thé H
    Nat Med; 2008 Dec; 14(12):1333-42. PubMed ID: 19029980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells.
    Duprez E; Wagner K; Koch H; Tenen DG
    EMBO J; 2003 Nov; 22(21):5806-16. PubMed ID: 14592978
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation.
    Vitaliano-Prunier A; Halftermeyer J; Ablain J; de Reynies A; Peres L; Le Bras M; Metzger D; de Thé H
    Blood; 2014 Dec; 124(25):3772-80. PubMed ID: 25258343
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway.
    Yoshida H; Kitamura K; Tanaka K; Omura S; Miyazaki T; Hachiya T; Ohno R; Naoe T
    Cancer Res; 1996 Jul; 56(13):2945-8. PubMed ID: 8674046
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro response to all-trans retinoic acid of acute promyelocytic leukemias with nonreciprocal PML/RARA or RARA/PML fusion genes.
    Mozziconacci MJ; Liberatore C; Brunel V; Grignani F; Arnoulet C; Ferrucci PF; Fernandez F; Sainty D; Pelicci PG; Birg F; Lafage-Pochitaloff M
    Genes Chromosomes Cancer; 1998 Jul; 22(3):241-50. PubMed ID: 9624536
    [TBL] [Abstract][Full Text] [Related]  

  • 9. All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
    Orfali N; O'Donovan TR; Cahill MR; Benjamin D; Nanus DM; McKenna SL; Gudas LJ; Mongan NP
    Eur J Haematol; 2020 Mar; 104(3):236-250. PubMed ID: 31811682
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells.
    Schläfli AM; Isakson P; Garattini E; Simonsen A; Tschan MP
    Sci Rep; 2017 Oct; 7(1):12980. PubMed ID: 29021535
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies.
    Ablain J; Leiva M; Peres L; Fonsart J; Anthony E; de Thé H
    J Exp Med; 2013 Apr; 210(4):647-53. PubMed ID: 23509325
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Therapy-induced PML/RARA proteolysis and acute promyelocytic leukemia cure.
    Nasr R; Lallemand-Breitenbach V; Zhu J; Guillemin MC; de Thé H
    Clin Cancer Res; 2009 Oct; 15(20):6321-6. PubMed ID: 19808868
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel treatment of acute promyelocytic leukemia: As₂O₃, retinoic acid and retinoid pharmacology.
    Zhu G
    Curr Pharm Biotechnol; 2013; 14(9):849-58. PubMed ID: 24433507
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagic degradation of an oncoprotein.
    Bøe SO; Simonsen A
    Autophagy; 2010 Oct; 6(7):964-5. PubMed ID: 20724820
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells.
    Jo S; Lee YL; Kim S; Lee H; Chung H
    Biochim Biophys Acta; 2016 Jul; 1863(7 Pt A):1499-509. PubMed ID: 27030546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selenite promotes all-trans retinoic acid-induced maturation of acute promyelocytic leukemia cells.
    Misra S; Selvam AK; Wallenberg M; Ambati A; Matolcsy A; Magalhaes I; Lauter G; Björnstedt M
    Oncotarget; 2016 Nov; 7(46):74686-74700. PubMed ID: 27732960
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Missense mutations in the PML/RARalpha ligand binding domain in ATRA-resistant As(2)O(3) sensitive relapsed acute promyelocytic leukemia.
    Marasca R; Zucchini P; Galimberti S; Leonardi G; Vaccari P; Donelli A; Luppi M; Petrini M; Torelli G
    Haematologica; 1999 Nov; 84(11):963-8. PubMed ID: 10553155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Eradication of acute promyelocytic leukemia-initiating cells by PML/RARA-targeting.
    Nasr R; de Thé H
    Int J Hematol; 2010 Jun; 91(5):742-7. PubMed ID: 20455087
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of
    Zhang F; Zhu YL; Deng WL; Zhu J; Zhang J
    J Leukoc Biol; 2017 Mar; 101(3):655-664. PubMed ID: 27605212
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia.
    Dos Santos GA; Kats L; Pandolfi PP
    J Exp Med; 2013 Dec; 210(13):2793-802. PubMed ID: 24344243
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.