108 related articles for article (PubMed ID: 25127466)
1. Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligands.
Sancineto L; Iraci N; Barreca ML; Massari S; Manfroni G; Corazza G; Cecchetti V; Marcello A; Daelemans D; Pannecouque C; Tabarrini O
Bioorg Med Chem; 2014 Sep; 22(17):4658-66. PubMed ID: 25127466
[TBL] [Abstract][Full Text] [Related]
2. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
Hopkins AL; Ren J; Milton J; Hazen RJ; Chan JH; Stuart DI; Stammers DK
J Med Chem; 2004 Nov; 47(24):5912-22. PubMed ID: 15537346
[TBL] [Abstract][Full Text] [Related]
3. Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives.
Tabarrini O; Massari S; Daelemans D; Meschini F; Manfroni G; Bottega L; Gatto B; Palumbo M; Pannecouque C; Cecchetti V
ChemMedChem; 2010 Nov; 5(11):1880-92. PubMed ID: 20928882
[TBL] [Abstract][Full Text] [Related]
4. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2.
Freeman GA; Andrews Iii CW; Hopkins AL; Lowell GS; Schaller LT; Cowan JR; Gonzales SS; Koszalka GW; Hazen RJ; Boone LR; Ferris RG; Creech KL; Roberts GB; Short SA; Weaver K; Reynolds DJ; Milton J; Ren J; Stuart DI; Stammers DK; Chan JH
J Med Chem; 2004 Nov; 47(24):5923-36. PubMed ID: 15537347
[TBL] [Abstract][Full Text] [Related]
5. Structural investigation of the naphthyridone scaffold: identification of a 1,6-naphthyridone derivative with potent and selective anti-HIV activity.
Tabarrini O; Massari S; Sancineto L; Daelemans D; Sabatini S; Manfroni G; Cecchetti V; Pannecouque C
ChemMedChem; 2011 Jul; 6(7):1249-57. PubMed ID: 21567967
[TBL] [Abstract][Full Text] [Related]
6. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase.
Wang Z; Vince R
Bioorg Med Chem Lett; 2008 Feb; 18(4):1293-6. PubMed ID: 18226894
[TBL] [Abstract][Full Text] [Related]
8. Studies on anti-HIV quinolones: new insights on the C-6 position.
Massari S; Daelemans D; Manfroni G; Sabatini S; Tabarrini O; Pannecouque C; Cecchetti V
Bioorg Med Chem; 2009 Jan; 17(2):667-74. PubMed ID: 19091580
[TBL] [Abstract][Full Text] [Related]
9. Structure-activity relationship study on anti-HIV 6-desfluoroquinolones.
Tabarrini O; Massari S; Daelemans D; Stevens M; Manfroni G; Sabatini S; Balzarini J; Cecchetti V; Pannecouque C; Fravolini A
J Med Chem; 2008 Sep; 51(17):5454-8. PubMed ID: 18710207
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
Vandurm P; Guiguen A; Cauvin C; Georges B; Le Van K; Michaux C; Cardona C; Mbemba G; Mouscadet JF; Hevesi L; Van Lint C; Wouters J
Eur J Med Chem; 2011 May; 46(5):1749-56. PubMed ID: 21385662
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of HQCAs with aryl or benzyl substituents on N-1 position as potential HIV-1 integrase inhibitors.
He QQ; Zhang X; Wu HQ; Gu SX; Ma XD; Yang LM; Zheng YT; Chen FE
Bioorg Med Chem; 2011 Sep; 19(18):5553-8. PubMed ID: 21862337
[TBL] [Abstract][Full Text] [Related]
12. Fused heterocyclic compounds bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 1: design, synthesis and biological evaluation of novel 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives.
Tian Y; Du D; Rai D; Wang L; Liu H; Zhan P; De Clercq E; Pannecouque C; Liu X
Bioorg Med Chem; 2014 Apr; 22(7):2052-9. PubMed ID: 24631361
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents.
Rawal RK; Tripathi R; Katti SB; Pannecouque C; De Clercq E
Eur J Med Chem; 2008 Dec; 43(12):2800-6. PubMed ID: 18242784
[TBL] [Abstract][Full Text] [Related]
14. Arylazolyl(azinyl)thioacetanilides. Part 16: Structure-based bioisosterism design, synthesis and biological evaluation of novel pyrimidinylthioacetanilides as potent HIV-1 inhibitors.
Li X; Lu X; Chen W; Liu H; Zhan P; Pannecouque C; Balzarini J; De Clercq E; Liu X
Bioorg Med Chem; 2014 Oct; 22(19):5290-7. PubMed ID: 25150090
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Zhang J; Zhan P; Wu J; Li Z; Jiang Y; Ge W; Pannecouque C; De Clercq E; Liu X
Bioorg Med Chem; 2011 Jul; 19(14):4366-76. PubMed ID: 21683601
[TBL] [Abstract][Full Text] [Related]
16. Discovery of 2-pyridone derivatives as potent HIV-1 NNRTIs using molecular hybridization based on crystallographic overlays.
Chen W; Zhan P; Rai D; De Clercq E; Pannecouque C; Balzarini J; Zhou Z; Liu H; Liu X
Bioorg Med Chem; 2014 Mar; 22(6):1863-72. PubMed ID: 24581546
[TBL] [Abstract][Full Text] [Related]
17. A new potential approach to block HIV-1 replication via protein-protein interaction and strand-transfer inhibition.
Ferro S; De Luca L; Lo Surdo G; Morreale F; Christ F; Debyser Z; Gitto R; Chimirri A
Bioorg Med Chem; 2014 Apr; 22(7):2269-79. PubMed ID: 24618511
[TBL] [Abstract][Full Text] [Related]
18. Fluorescence polarization for the evaluation of small-molecule inhibitors of PCAF BRD/Tat-AcK50 association.
Hu P; Wang X; Zhang B; Zhang S; Wang Q; Wang Z
ChemMedChem; 2014 May; 9(5):928-31. PubMed ID: 24474698
[TBL] [Abstract][Full Text] [Related]
19. Discovery of piperidine-linked pyridine analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Chen X; Li Y; Ding S; Balzarini J; Pannecouque C; De Clercq E; Liu H; Liu X
ChemMedChem; 2013 Jul; 8(7):1117-26. PubMed ID: 23650275
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings.
Deng BL; Cullen MD; Zhou Z; Hartman TL; Buckheit RW; Pannecouque C; De Clercq E; Fanwick PE; Cushman M
Bioorg Med Chem; 2006 Apr; 14(7):2366-74. PubMed ID: 16321539
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]