BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 25129047)

  • 1. Regioselective hydroxylation of 17β-estradiol by mutants of CYP102A1 from Bacillus megaterium.
    Cha GS; Ryu SH; Ahn T; Yun CH
    Biotechnol Lett; 2014 Dec; 36(12):2501-6. PubMed ID: 25129047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regioselective hydroxylation of omeprazole enantiomers by bacterial CYP102A1 mutants.
    Ryu SH; Park BY; Kim SY; Park SH; Jung HJ; Park M; Park KD; Ahn T; Kang HS; Yun CH
    Drug Metab Dispos; 2014 Sep; 42(9):1493-7. PubMed ID: 25008345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants.
    Kim KH; Kang JY; Kim DH; Park SH; Park SH; Kim D; Park KD; Lee YJ; Jung HC; Pan JG; Ahn T; Yun CH
    Drug Metab Dispos; 2011 Jan; 39(1):140-50. PubMed ID: 20962060
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite.
    Jang HH; Ryu SH; Le TK; Doan TT; Nguyen TH; Park KD; Yim DE; Kim DH; Kang CK; Ahn T; Kang HS; Yun CH
    Biotechnol Lett; 2017 Jan; 39(1):105-112. PubMed ID: 27640009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Generation of the human metabolite piceatannol from the anticancer-preventive agent resveratrol by bacterial cytochrome P450 BM3.
    Kim DH; Ahn T; Jung HC; Pan JG; Yun CH
    Drug Metab Dispos; 2009 May; 37(5):932-6. PubMed ID: 19237510
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs.
    Venkataraman H; Verkade-Vreeker MC; Capoferri L; Geerke DP; Vermeulen NP; Commandeur JN
    Bioorg Med Chem; 2014 Oct; 22(20):5613-20. PubMed ID: 24999003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies.
    Rea V; Kolkman AJ; Vottero E; Stronks EJ; Ampt KA; Honing M; Vermeulen NP; Wijmenga SS; Commandeur JN
    Biochemistry; 2012 Jan; 51(3):750-60. PubMed ID: 22208729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Generation of human metabolites of 7-ethoxycoumarin by bacterial cytochrome P450 BM3.
    Kim DH; Kim KH; Kim DH; Liu KH; Jung HC; Pan JG; Yun CH
    Drug Metab Dispos; 2008 Nov; 36(11):2166-70. PubMed ID: 18669587
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Highly regioselective hydroxylation of polydatin, a resveratrol glucoside, for one-step synthesis of astringin, a piceatannol glucoside, by P450 BM3.
    Le TK; Jang HH; Nguyen HT; Doan TT; Lee GY; Park KD; Ahn T; Joung YH; Kang HS; Yun CH
    Enzyme Microb Technol; 2017 Feb; 97():34-42. PubMed ID: 28010771
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Control of the stereo-selectivity of styrene epoxidation by cytochrome P450 BM3 using structure-based mutagenesis.
    Huang WC; Cullis PM; Raven EL; Roberts GC
    Metallomics; 2011 Apr; 3(4):410-6. PubMed ID: 21240430
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Screening of a minimal enriched P450 BM3 mutant library for hydroxylation of cyclic and acyclic alkanes.
    Weber E; Seifert A; Antonovici M; Geinitz C; Pleiss J; Urlacher VB
    Chem Commun (Camb); 2011 Jan; 47(3):944-6. PubMed ID: 21079837
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chimeric cytochromes P450 engineered by domain swapping and random mutagenesis for producing human metabolites of drugs.
    Kang JY; Ryu SH; Park SH; Cha GS; Kim DH; Kim KH; Hong AW; Ahn T; Pan JG; Joung YH; Kang HS; Yun CH
    Biotechnol Bioeng; 2014 Jul; 111(7):1313-22. PubMed ID: 24474032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11.
    Vottero E; Rea V; Lastdrager J; Honing M; Vermeulen NP; Commandeur JN
    J Biol Inorg Chem; 2011 Aug; 16(6):899-912. PubMed ID: 21567268
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
    Huang WC; Westlake AC; Maréchal JD; Joyce MG; Moody PC; Roberts GC
    J Mol Biol; 2007 Oct; 373(3):633-51. PubMed ID: 17868686
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Desaturation of alkylbenzenes by cytochrome P450(BM3) (CYP102A1).
    Whitehouse CJ; Bell SG; Wong LL
    Chemistry; 2008; 14(35):10905-8. PubMed ID: 19003834
    [No Abstract]   [Full Text] [Related]  

  • 16. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
    Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
    Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities.
    Yun CH; Kim KH; Kim DH; Jung HC; Pan JG
    Trends Biotechnol; 2007 Jul; 25(7):289-98. PubMed ID: 17532492
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Engineering cytochrome P450 BM3 of Bacillus megaterium for terminal oxidation of palmitic acid.
    Brühlmann F; Fourage L; Ullmann C; Haefliger OP; Jeckelmann N; Dubois C; Wahler D
    J Biotechnol; 2014 Aug; 184():17-26. PubMed ID: 24833423
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Altering the regioselectivity of the subterminal fatty acid hydroxylase P450 BM-3 towards gamma- and delta-positions.
    Dietrich M; Do TA; Schmid RD; Pleiss J; Urlacher VB
    J Biotechnol; 2009 Jan; 139(1):115-7. PubMed ID: 18984016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bacillus megaterium CYP102A1 oxidation of acyl homoserine lactones and acyl homoserines.
    Chowdhary PK; Keshavan N; Nguyen HQ; Peterson JA; González JE; Haines DC
    Biochemistry; 2007 Dec; 46(50):14429-37. PubMed ID: 18020460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.