200 related articles for article (PubMed ID: 25129170)
1. 'Carba'-carfentanil (trans isomer): a μ opioid receptor (MOR) partial agonist with a distinct binding mode.
Weltrowska G; Lemieux C; Chung NN; Guo JJ; Wilkes BC; Schiller PW
Bioorg Med Chem; 2014 Sep; 22(17):4581-6. PubMed ID: 25129170
[TBL] [Abstract][Full Text] [Related]
2. "Carba"-analogues of fentanyl are opioid receptor agonists.
Weltrowska G; Chung NN; Lemieux C; Guo J; Lu Y; Wilkes BC; Schiller PW
J Med Chem; 2010 Apr; 53(7):2875-81. PubMed ID: 20218625
[TBL] [Abstract][Full Text] [Related]
3. Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors.
Eshleman AJ; Nagarajan S; Wolfrum KM; Reed JF; Nilsen A; Torralva R; Janowsky A
Biochem Pharmacol; 2020 Dec; 182():114293. PubMed ID: 33091380
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of Carfentanil Amide Opioids Using the Ugi Multicomponent Reaction.
Váradi A; Palmer TC; Haselton N; Afonin D; Subrath JJ; Le Rouzic V; Hunkele A; Pasternak GW; Marrone GF; Borics A; Majumdar S
ACS Chem Neurosci; 2015 Sep; 6(9):1570-7. PubMed ID: 26148793
[TBL] [Abstract][Full Text] [Related]
5. Fentanyl-Type Antagonist of the μ-Opioid Receptor: Important Role of Axial Chirality in the Active Conformation.
Arita H; Tanaka R; Kikukawa S; Tomizawa T; Sakata H; Funada M; Tomiyama K; Hashimoto M; Tasaka T; Tabata H; Nakamura K; Makino K; Oshitari T; Natsugari H; Takahashi H
J Med Chem; 2024 Jun; 67(12):10447-10463. PubMed ID: 38869493
[TBL] [Abstract][Full Text] [Related]
6. Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective μ Opioid Receptor Agonists.
Huang H; Li X; Guo W; Zhu C; Qian Y; Shen Q; Xu X; Li W; Wang Y; Fu W
ACS Chem Neurosci; 2021 Jan; 12(2):285-299. PubMed ID: 32852933
[TBL] [Abstract][Full Text] [Related]
7. How μ-opioid receptor recognizes fentanyl.
Vo QN; Mahinthichaichan P; Shen J; Ellis CR
Nat Commun; 2021 Feb; 12(1):984. PubMed ID: 33579956
[TBL] [Abstract][Full Text] [Related]
8. Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor.
Lu YF; Xu H; Liu-Chen LY; Chen C; Partilla JS; Brine GA; Carroll FI; Rice KC; Lai J; Porreca F; Sadee W; Rothman RB
Synapse; 1998 Feb; 28(2):117-24. PubMed ID: 9450512
[TBL] [Abstract][Full Text] [Related]
9. Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR Affinities.
Harland AA; Yeomans L; Griggs NW; Anand JP; Pogozheva ID; Jutkiewicz EM; Traynor JR; Mosberg HI
J Med Chem; 2015 Nov; 58(22):8952-69. PubMed ID: 26524472
[TBL] [Abstract][Full Text] [Related]
10. Effectiveness comparisons of G-protein biased and unbiased mu opioid receptor ligands in warm water tail-withdrawal and drug discrimination in male and female rats.
Schwienteck KL; Faunce KE; Rice KC; Obeng S; Zhang Y; Blough BE; Grim TW; Negus SS; Banks ML
Neuropharmacology; 2019 May; 150():200-209. PubMed ID: 30660628
[TBL] [Abstract][Full Text] [Related]
11. Opioid peptide receptor studies, 11: involvement of Tyr148, Trp318 and His319 of the rat mu-opioid receptor in binding of mu-selective ligands.
Xu H; Lu YF; Partilla JS; Zheng QX; Wang JB; Brine GA; Carroll FI; Rice KC; Chen KX; Chi ZQ; Rothman RB
Synapse; 1999 Apr; 32(1):23-8. PubMed ID: 10188634
[TBL] [Abstract][Full Text] [Related]
12. Binding preference at the μ-opioid receptor underlies distinct pharmacology of cyclopropyl versus valeryl analogs of fentanyl.
Xie B; Le Rouzic VP; Goldberg A; Tsai MM; Chen L; Zhang T; Sinha A; Pan YX; Baumann MH; Shi L
Neuropharmacology; 2023 Apr; 227():109442. PubMed ID: 36731721
[TBL] [Abstract][Full Text] [Related]
13. Effects of N-Substitutions on the Tetrahydroquinoline (THQ) Core of Mixed-Efficacy μ-Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Ligands.
Harland AA; Bender AM; Griggs NW; Gao C; Anand JP; Pogozheva ID; Traynor JR; Jutkiewicz EM; Mosberg HI
J Med Chem; 2016 May; 59(10):4985-98. PubMed ID: 27148755
[TBL] [Abstract][Full Text] [Related]
14. Molecular docking reveals a novel binding site model for fentanyl at the mu-opioid receptor.
Subramanian G; Paterlini MG; Portoghese PS; Ferguson DM
J Med Chem; 2000 Feb; 43(3):381-91. PubMed ID: 10669565
[TBL] [Abstract][Full Text] [Related]
15. Role of Efficacy as a Determinant of Locomotor Activation by Mu Opioid Receptor Ligands in Female and Male Mice.
Santos EJ; Banks ML; Negus SS
J Pharmacol Exp Ther; 2022 Jul; 382(1):44-53. PubMed ID: 35489781
[TBL] [Abstract][Full Text] [Related]
16. Pentapeptides displaying mu opioid receptor agonist and delta opioid receptor partial agonist/antagonist properties.
Purington LC; Pogozheva ID; Traynor JR; Mosberg HI
J Med Chem; 2009 Dec; 52(23):7724-31. PubMed ID: 19788201
[TBL] [Abstract][Full Text] [Related]
17. Modulation of opioid receptor ligand affinity and efficacy using active and inactive state receptor models.
Anand JP; Purington LC; Pogozheva ID; Traynor JR; Mosberg HI
Chem Biol Drug Des; 2012 Nov; 80(5):763-70. PubMed ID: 22882801
[TBL] [Abstract][Full Text] [Related]
18. Low μ-Opioid Receptor Status in Alcohol Dependence Identified by Combined Positron Emission Tomography and Post-Mortem Brain Analysis.
Hermann D; Hirth N; Reimold M; Batra A; Smolka MN; Hoffmann S; Kiefer F; Noori HR; Sommer WH; Reischl G; la Fougère C; Mann K; Spanagel R; Hansson AC
Neuropsychopharmacology; 2017 Feb; 42(3):606-614. PubMed ID: 27510425
[TBL] [Abstract][Full Text] [Related]
19. Building up analgesia in humans via the endogenous μ-opioid system by combining placebo and active tDCS: a preliminary report.
DosSantos MF; Martikainen IK; Nascimento TD; Love TM; DeBoer MD; Schambra HM; Bikson M; Zubieta JK; DaSilva AF
PLoS One; 2014; 9(7):e102350. PubMed ID: 25029273
[TBL] [Abstract][Full Text] [Related]
20. Investigation of the interaction between the atypical agonist c[YpwFG] and MOR.
Gentilucci L; Squassabia F; De Marco R; Artali R; Cardillo G; Tolomelli A; Spampinato S; Bedini A
FEBS J; 2008 May; 275(9):2315-37. PubMed ID: 18397320
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
