712 related articles for article (PubMed ID: 25131183)
1. Targeting Th17 cells in autoimmune diseases.
Yang J; Sundrud MS; Skepner J; Yamagata T
Trends Pharmacol Sci; 2014 Oct; 35(10):493-500. PubMed ID: 25131183
[TBL] [Abstract][Full Text] [Related]
2. Inhibiting RORγt/Th17 axis for autoimmune disorders.
Isono F; Fujita-Sato S; Ito S
Drug Discov Today; 2014 Aug; 19(8):1205-11. PubMed ID: 24792721
[TBL] [Abstract][Full Text] [Related]
3. Transcription Factor Retinoid-Related Orphan Receptor γt: A Promising Target for the Treatment of Psoriasis.
Tang L; Yang X; Liang Y; Xie H; Dai Z; Zheng G
Front Immunol; 2018; 9():1210. PubMed ID: 29899748
[TBL] [Abstract][Full Text] [Related]
4. Targeting Th17 Cells with Small Molecules and Small Interference RNA.
Lin H; Song P; Zhao Y; Xue LJ; Liu Y; Chu CQ
Mediators Inflamm; 2015; 2015():290657. PubMed ID: 26792955
[TBL] [Abstract][Full Text] [Related]
5. RORs in autoimmune disease.
Chang MR; Rosen H; Griffin PR
Curr Top Microbiol Immunol; 2014; 378():171-82. PubMed ID: 24728598
[TBL] [Abstract][Full Text] [Related]
6. Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies.
Maddur MS; Miossec P; Kaveri SV; Bayry J
Am J Pathol; 2012 Jul; 181(1):8-18. PubMed ID: 22640807
[TBL] [Abstract][Full Text] [Related]
7. Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell Differentiation.
Ding Q; Zhao M; Yu B; Bai C; Huang Z
PLoS One; 2015; 10(9):e0137711. PubMed ID: 26368822
[TBL] [Abstract][Full Text] [Related]
8. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.
Skepner J; Ramesh R; Trocha M; Schmidt D; Baloglu E; Lobera M; Carlson T; Hill J; Orband-Miller LA; Barnes A; Boudjelal M; Sundrud M; Ghosh S; Yang J
J Immunol; 2014 Mar; 192(6):2564-75. PubMed ID: 24516202
[TBL] [Abstract][Full Text] [Related]
9. Targeting Th17 Effector Cytokines for the Treatment of Autoimmune Diseases.
Yamagata T; Skepner J; Yang J
Arch Immunol Ther Exp (Warsz); 2015 Dec; 63(6):405-14. PubMed ID: 26358867
[TBL] [Abstract][Full Text] [Related]
10. RORγt-specific transcriptional interactomic inhibition suppresses autoimmunity associated with TH17 cells.
Park TY; Park SD; Cho JY; Moon JS; Kim NY; Park K; Seong RH; Lee SW; Morio T; Bothwell AL; Lee SK
Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18673-8. PubMed ID: 25527718
[TBL] [Abstract][Full Text] [Related]
11. The immunomodulatory effects of TNF-α inhibitors on human Th17 cells via RORγt histone acetylation.
Lin YC; Lin YC; Wu CC; Huang MY; Tsai WC; Hung CH; Kuo PL
Oncotarget; 2017 Jan; 8(5):7559-7571. PubMed ID: 27926504
[TBL] [Abstract][Full Text] [Related]
12. Retinoic acid receptor-related orphan receptor gamma-t (RORγt) inhibitors in clinical development for the treatment of autoimmune diseases: a patent review (2016-present).
Sun N; Guo H; Wang Y
Expert Opin Ther Pat; 2019 Sep; 29(9):663-674. PubMed ID: 31403347
[No Abstract] [Full Text] [Related]
13. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.
Ivanov II; McKenzie BS; Zhou L; Tadokoro CE; Lepelley A; Lafaille JJ; Cua DJ; Littman DR
Cell; 2006 Sep; 126(6):1121-33. PubMed ID: 16990136
[TBL] [Abstract][Full Text] [Related]
14. IL-21 is a central memory T cell-associated cytokine that inhibits the generation of pathogenic Th1/17 effector cells.
Kastirr I; Maglie S; Paroni M; Alfen JS; Nizzoli G; Sugliano E; Crosti MC; Moro M; Steckel B; Steinfelder S; Stölzel K; Romagnani C; Botti F; Caprioli F; Pagani M; Abrignani S; Geginat J
J Immunol; 2014 Oct; 193(7):3322-31. PubMed ID: 25172491
[TBL] [Abstract][Full Text] [Related]
15. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
Huh JR; Leung MW; Huang P; Ryan DA; Krout MR; Malapaka RR; Chow J; Manel N; Ciofani M; Kim SV; Cuesta A; Santori FR; Lafaille JJ; Xu HE; Gin DY; Rastinejad F; Littman DR
Nature; 2011 Apr; 472(7344):486-90. PubMed ID: 21441909
[TBL] [Abstract][Full Text] [Related]
16. Th17 cell development: from the cradle to the grave.
Zúñiga LA; Jain R; Haines C; Cua DJ
Immunol Rev; 2013 Mar; 252(1):78-88. PubMed ID: 23405896
[TBL] [Abstract][Full Text] [Related]
17. Transcriptional Regulators of T Helper 17 Cell Differentiation in Health and Autoimmune Diseases.
Capone A; Volpe E
Front Immunol; 2020; 11():348. PubMed ID: 32226427
[TBL] [Abstract][Full Text] [Related]
18. IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis.
Yamashita T; Iwakura T; Matsui K; Kawaguchi H; Obana M; Hayama A; Maeda M; Izumi Y; Komuro I; Ohsugi Y; Fujimoto M; Naka T; Kishimoto T; Nakayama H; Fujio Y
Cardiovasc Res; 2011 Sep; 91(4):640-8. PubMed ID: 21622681
[TBL] [Abstract][Full Text] [Related]
19. Small molecule inhibitors of RORγt: targeting Th17 cells and other applications.
Huh JR; Littman DR
Eur J Immunol; 2012 Sep; 42(9):2232-7. PubMed ID: 22949321
[TBL] [Abstract][Full Text] [Related]
20. Expression of Th17-related genes in PHA/IL-2-activated human T cells by Fas signaling via caspase-1- and Stat3-dependent pathway.
Su CC; Lin HC; Lin YP; Shan YS; Yang BC
Cell Immunol; 2013 Feb; 281(2):101-10. PubMed ID: 23590971
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
