These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 25137025)

  • 1. Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.
    Diaz-Rodriguez E; Garcia-Rendueles AR; Ibáñez-Costa A; Gutierrez-Pascual E; Garcia-Lavandeira M; Leal A; Japon MA; Soto A; Venegas E; Tinahones FJ; Garcia-Arnes JA; Benito P; Angeles Galvez M; Jimenez-Reina L; Bernabeu I; Dieguez C; Luque RM; Castaño JP; Alvarez CV
    Endocrinology; 2014 Nov; 155(11):4329-40. PubMed ID: 25137025
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegaly.
    Chenlo M; Rodriguez-Gomez IA; Serramito R; Garcia-Rendueles AR; Villar-Taibo R; Fernandez-Rodriguez E; Perez-Romero S; Suarez-Fariña M; Garcia-Allut A; Cabezas-Agricola JM; Rodriguez-Garcia J; Lear PV; Alvarez-San Martin RM; Alvarez-Escola C; Bernabeu I; Alvarez CV
    EBioMedicine; 2019 May; 43():537-552. PubMed ID: 30975543
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct promoter induction of p19Arf by Pit-1 explains the dependence receptor RET/Pit-1/p53-induced apoptosis in the pituitary somatotroph cells.
    Diaz-Rodriguez E; García-Lavandeira M; Perez-Romero S; Senra A; Cañibano C; Palmero I; Borrello MG; Dieguez C; Alvarez CV
    Oncogene; 2012 Jun; 31(23):2824-35. PubMed ID: 22020338
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth.
    Cañibano C; Rodriguez NL; Saez C; Tovar S; Garcia-Lavandeira M; Borrello MG; Vidal A; Costantini F; Japon M; Dieguez C; Alvarez CV
    EMBO J; 2007 Apr; 26(8):2015-28. PubMed ID: 17380130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glial-derived neurotropic factor and RET gene expression in normal human anterior pituitary cell types and in pituitary tumors.
    Japón MA; Urbano AG; Sáez C; Segura DI; Cerro AL; Diéguez C; Alvarez CV
    J Clin Endocrinol Metab; 2002 Apr; 87(4):1879-84. PubMed ID: 11932334
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas.
    Garcia-Rendueles AR; Chenlo M; Oroz-Gonjar F; Solomou A; Mistry A; Barry S; Gaston-Massuet C; Garcia-Lavandeira M; Perez-Romero S; Suarez-Fariña M; Pradilla-Dieste A; Dieguez C; Mehlen P; Korbonits M; Alvarez CV
    Oncogene; 2021 Nov; 40(45):6354-6368. PubMed ID: 34588620
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Infrequent detectable somatic mutations of the RET and glial cell line-derived neurotrophic factor (GDNF) genes in human pituitary adenomas.
    Yoshimoto K; Tanaka C; Moritani M; Shimizu E; Yamaoka T; Yamada S; Sano T; Itakura M
    Endocr J; 1999 Feb; 46(1):199-207. PubMed ID: 10426588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional role of the RET dependence receptor, GFRa co-receptors and ligands in the pituitary.
    Garcia-Lavandeira M; Diaz-Rodriguez E; Garcia-Rendueles MER; Rodrigues JS; Perez-Romero S; Bravo SB; Alvarez CV
    Front Horm Res; 2010; 38():127-138. PubMed ID: 20616503
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of SNARE proteins in human pituitary adenomas: targeted secretion inhibitors as a new strategy for the treatment of acromegaly?
    Garcia EA; Trivellin G; Aflorei ED; Powell M; Grieve J; Alusi G; Pobereskin L; Shariati B; Cudlip S; Roncaroli F; Mendoza N; Grossman AB; Harper EA; Korbonits M
    J Clin Endocrinol Metab; 2013 Dec; 98(12):E1918-26. PubMed ID: 24152687
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ZAC1 and SSTR2 are downregulated in non-functioning pituitary adenomas but not in somatotropinomas.
    Vieria Neto L; Wildemberg LE; Colli LM; Kasuki L; Marques NV; Moraes AB; Gasparetto EL; Takiya CM; Castro M; Gadelha MR
    PLoS One; 2013; 8(10):e77406. PubMed ID: 24098585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas.
    Grande IPP; Amorim PVGH; Freire ACTB; Jallad RS; Musolino NR; Cescato VA; da Silva GO; Bronstein MD; Trarbach EB
    Pituitary; 2018 Aug; 21(4):355-361. PubMed ID: 29564694
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression analysis of dopamine receptor subtypes in normal human pituitaries, nonfunctioning pituitary adenomas and somatotropinomas, and the association between dopamine and somatostatin receptors with clinical response to octreotide-LAR in acromegaly.
    Neto LV; Machado Ede O; Luque RM; Taboada GF; Marcondes JB; Chimelli LM; Quintella LP; Niemeyer P; de Carvalho DP; Kineman RD; Gadelha MR
    J Clin Endocrinol Metab; 2009 Jun; 94(6):1931-7. PubMed ID: 19293270
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential effects of glial cell line-derived neurotrophic factor and neurturin in RET/GFRalpha1-expressing cells.
    Lee RH; Wong WL; Chan CH; Chan SY
    J Neurosci Res; 2006 Jan; 83(1):80-90. PubMed ID: 16294336
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Retinoic acid-induced apoptosis of the CHP134 neuroblastoma cell line is associated with nuclear accumulation of p53 and is rescued by the GDNF/Ret signal.
    Takada N; Isogai E; Kawamoto T; Nakanishi H; Todo S; Nakagawara A
    Med Pediatr Oncol; 2001 Jan; 36(1):122-6. PubMed ID: 11464863
    [TBL] [Abstract][Full Text] [Related]  

  • 15. STAT3 upregulation in pituitary somatotroph adenomas induces growth hormone hypersecretion.
    Zhou C; Jiao Y; Wang R; Ren SG; Wawrowsky K; Melmed S
    J Clin Invest; 2015 Apr; 125(4):1692-702. PubMed ID: 25774503
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.
    Sawai H; Okada Y; Kazanjian K; Kim J; Hasan S; Hines OJ; Reber HA; Hoon DS; Eibl G
    Cancer Res; 2005 Dec; 65(24):11536-44. PubMed ID: 16357163
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional characterization of DLK1/MEG3 locus on chromosome 14q32.2 reveals the differentiation of pituitary neuroendocrine tumors.
    Chen Y; Gao H; Liu Q; Xie W; Li B; Cheng S; Guo J; Fang Q; Zhu H; Wang Z; Wang J; Li C; Zhang Y
    Aging (Albany NY); 2020 Dec; 13(1):1422-1439. PubMed ID: 33472171
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of the antiapoptotic gene seladin-1 and octreotide-induced apoptosis in growth hormone-secreting and nonfunctioning pituitary adenomas.
    Luciani P; Gelmini S; Ferrante E; Lania A; Benvenuti S; Baglioni S; Mantovani G; Cellai I; Ammannati F; Spada A; Serio M; Peri A
    J Clin Endocrinol Metab; 2005 Nov; 90(11):6156-61. PubMed ID: 16091489
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acidic oligosaccharide sugar chain, a marine-derived oligosaccharide, activates human glial cell line-derived neurotrophic factor signaling.
    Wang XJ; Chen XH; Yang XY; Geng MY; Wang LM
    Neurosci Lett; 2007 May; 417(2):176-80. PubMed ID: 17403572
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glial cell line-derived neurotrophic factor and its receptor ret is a novel ligand-receptor complex critical for survival response during podocyte injury.
    Tsui CC; Shankland SJ; Pierchala BA
    J Am Soc Nephrol; 2006 Jun; 17(6):1543-52. PubMed ID: 16672314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.