BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 25137073)

  • 1. pH dependence of conformational fluctuations of the protein backbone.
    Richman DE; Majumdar A; García-Moreno E B
    Proteins; 2014 Nov; 82(11):3132-43. PubMed ID: 25137073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural origins of high apparent dielectric constants experienced by ionizable groups in the hydrophobic core of a protein.
    Chimenti MS; Castañeda CA; Majumdar A; García-Moreno E B
    J Mol Biol; 2011 Jan; 405(2):361-77. PubMed ID: 21059359
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular determinants of the pKa values of Asp and Glu residues in staphylococcal nuclease.
    Castañeda CA; Fitch CA; Majumdar A; Khangulov V; Schlessman JL; García-Moreno BE
    Proteins; 2009 Nov; 77(3):570-88. PubMed ID: 19533744
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational consequences of ionization of Lys, Asp, and Glu buried at position 66 in staphylococcal nuclease.
    Karp DA; Stahley MR; García-Moreno B
    Biochemistry; 2010 May; 49(19):4138-46. PubMed ID: 20329780
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular mechanisms of pH-driven conformational transitions of proteins: insights from continuum electrostatics calculations of acid unfolding.
    Fitch CA; Whitten ST; Hilser VJ; García-Moreno E B
    Proteins; 2006 Apr; 63(1):113-26. PubMed ID: 16400648
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The pH-dependence of amide chemical shift of Asp/Glu reflects its pKa in intrinsically disordered proteins with only local interactions.
    Pujato M; Navarro A; Versace R; Mancusso R; Ghose R; Tasayco ML
    Biochim Biophys Acta; 2006 Jul; 1764(7):1227-33. PubMed ID: 16787768
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformational Reorganization Coupled to the Ionization of Internal Lys Residues in Proteins.
    Richman DE; Majumdar A; García-Moreno E B
    Biochemistry; 2015 Sep; 54(38):5888-97. PubMed ID: 26335188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A buried lysine that titrates with a normal pKa: role of conformational flexibility at the protein-water interface as a determinant of pKa values.
    Harms MJ; Schlessman JL; Chimenti MS; Sue GR; Damjanović A; García-Moreno B
    Protein Sci; 2008 May; 17(5):833-45. PubMed ID: 18369193
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural plasticity of staphylococcal nuclease probed by perturbation with pressure and pH.
    Kitahara R; Hata K; Maeno A; Akasaka K; Chimenti MS; Garcia-Moreno E B; Schroer MA; Jeworrek C; Tolan M; Winter R; Roche J; Roumestand C; Montet de Guillen K; Royer CA
    Proteins; 2011 Apr; 79(4):1293-305. PubMed ID: 21254234
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Electrostatic effects in a network of polar and ionizable groups in staphylococcal nuclease.
    Baran KL; Chimenti MS; Schlessman JL; Fitch CA; Herbst KJ; Garcia-Moreno BE
    J Mol Biol; 2008 Jun; 379(5):1045-62. PubMed ID: 18499123
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Coupled Ionization-Conformational Equilibrium Is Required To Understand the Properties of Ionizable Residues in the Hydrophobic Interior of Staphylococcal Nuclease.
    Liu J; Swails J; Zhang JZH; He X; Roitberg AE
    J Am Chem Soc; 2018 Feb; 140(5):1639-1648. PubMed ID: 29308643
    [TBL] [Abstract][Full Text] [Related]  

  • 12. pH dependence of amide chemical shifts in natively disordered polypeptides detects medium-range interactions with ionizable residues.
    Pujato M; Bracken C; Mancusso R; Cataldi M; Tasayco ML
    Biophys J; 2005 Nov; 89(5):3293-302. PubMed ID: 16113108
    [TBL] [Abstract][Full Text] [Related]  

  • 13. pH-Dependent Conformational Changes Due to Ionizable Residues in a Hydrophobic Protein Interior: The Study of L25K and L125K Variants of SNase.
    Sarkar A; Gupta PL; Roitberg AE
    J Phys Chem B; 2019 Jul; 123(27):5742-5754. PubMed ID: 31260304
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conformational relaxation and water penetration coupled to ionization of internal groups in proteins.
    Damjanović A; Brooks BR; García-Moreno B
    J Phys Chem A; 2011 Apr; 115(16):4042-53. PubMed ID: 21428436
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The pK(a) values of acidic and basic residues buried at the same internal location in a protein are governed by different factors.
    Harms MJ; Castañeda CA; Schlessman JL; Sue GR; Isom DG; Cannon BR; García-Moreno E B
    J Mol Biol; 2009 May; 389(1):34-47. PubMed ID: 19324049
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Experimental pK(a) values of buried residues: analysis with continuum methods and role of water penetration.
    Fitch CA; Karp DA; Lee KK; Stites WE; Lattman EE; García-Moreno E B
    Biophys J; 2002 Jun; 82(6):3289-304. PubMed ID: 12023252
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Local Backbone Flexibility as a Determinant of the Apparent pK
    Peck MT; Ortega G; De Luca-Johnson JN; Schlessman JL; Robinson AC; García-Moreno E B
    Biochemistry; 2017 Oct; 56(40):5338-5346. PubMed ID: 28952715
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Charges in Hydrophobic Environments: A Strategy for Identifying Alternative States in Proteins.
    Robinson AC; Majumdar A; Schlessman JL; García-Moreno E B
    Biochemistry; 2017 Jan; 56(1):212-218. PubMed ID: 28009501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Uncovering pH-dependent transient states of proteins with buried ionizable residues.
    Goh GB; Laricheva EN; Brooks CL
    J Am Chem Soc; 2014 Jun; 136(24):8496-9. PubMed ID: 24842060
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Backbone relaxation coupled to the ionization of internal groups in proteins: a self-guided Langevin dynamics study.
    Damjanović A; Wu X; García-Moreno E B; Brooks BR
    Biophys J; 2008 Nov; 95(9):4091-101. PubMed ID: 18641078
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.