These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 25139751)

  • 1. Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.
    Nagao S; Yamane Y; Funasaka S; Tanaka K; Miyazaki K; Kotake Y; Kamata J; Watanabe-Miyano S; Toyama O; Ozawa Y; Mizui Y; Okamoto K; Ito D
    Bioorg Med Chem; 2014 Oct; 22(19):5513-29. PubMed ID: 25139751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors.
    Yasuda Y; Arakawa T; Nawata Y; Shimada S; Oishi S; Fujii N; Nishimura S; Hattori A; Kakeya H
    Bioorg Med Chem; 2015 Apr; 23(8):1776-87. PubMed ID: 25773014
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors.
    Xia Y; Choi HK; Lee K
    Eur J Med Chem; 2012 Mar; 49():24-40. PubMed ID: 22305612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
    Chau NM; Rogers P; Aherne W; Carroll V; Collins I; McDonald E; Workman P; Ashcroft M
    Cancer Res; 2005 Jun; 65(11):4918-28. PubMed ID: 15930314
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
    Rapisarda A; Uranchimeg B; Scudiero DA; Selby M; Sausville EA; Shoemaker RH; Melillo G
    Cancer Res; 2002 Aug; 62(15):4316-24. PubMed ID: 12154035
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening.
    Zhang M; Zhu W; Li Y
    Eur J Med Chem; 2013 Apr; 62():301-10. PubMed ID: 23376248
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and characterization of small molecule inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening.
    Zhang M; Zhu W; Ding N; Zhang W; Li Y
    Bioorg Med Chem Lett; 2013 Apr; 23(7):2225-9. PubMed ID: 23434226
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.
    Tan C; de Noronha RG; Roecker AJ; Pyrzynska B; Khwaja F; Zhang Z; Zhang H; Teng Q; Nicholson AC; Giannakakou P; Zhou W; Olson JJ; Pereira MM; Nicolaou KC; Van Meir EG
    Cancer Res; 2005 Jan; 65(2):605-12. PubMed ID: 15695405
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strongylophorines: natural product inhibitors of hypoxia-inducible factor-1 transcriptional pathway.
    Mohammed KA; Jadulco RC; Bugni TS; Harper MK; Sturdy M; Ireland CM
    J Med Chem; 2008 Mar; 51(5):1402-5. PubMed ID: 18278856
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships study of neolamellarin A and its analogues as hypoxia inducible factor-1 (HIF-1) inhibitors.
    Li G; Dong H; Ma Y; Shao K; Li Y; Wu X; Wang S; Shao Y; Zhao W
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2327-2331. PubMed ID: 31281016
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxia-inducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation.
    Jin X; Jin HR; Lee D; Lee JH; Kim SK; Lee JJ
    Eur J Pharmacol; 2008 Sep; 592(1-3):41-7. PubMed ID: 18639543
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cardenolides from Calotropis gigantea as potent inhibitors of hypoxia-inducible factor-1 transcriptional activity.
    Parhira S; Zhu GY; Chen M; Bai LP; Jiang ZH
    J Ethnopharmacol; 2016 Dec; 194():930-936. PubMed ID: 27793783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular redox status regulates hypoxia inducible factor-1 activity. Role in tumour development.
    Martínez-Sánchez G; Giuliani A
    J Exp Clin Cancer Res; 2007 Mar; 26(1):39-50. PubMed ID: 17550131
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
    Shu G; Mi X; Cai J; Zhang X; Yin W; Yang X; Li Y; Chen L; Deng X
    Toxicol Lett; 2013 Oct; 222(2):91-101. PubMed ID: 23933019
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, Binding Affinity Analysis, and
    Dawn Woodfield J; Bhardwaj A; Bergman C; Wuest F
    ChemMedChem; 2022 Jan; 17(1):e202100544. PubMed ID: 34595843
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors.
    Tan C; de Noronha RG; Devi NS; Jabbar AA; Kaluz S; Liu Y; Mooring SR; Nicolaou KC; Wang B; Van Meir EG
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5528-32. PubMed ID: 21831638
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues.
    Xia Y; Jin Y; Kaur N; Choi Y; Lee K
    Eur J Med Chem; 2011 Jun; 46(6):2386-96. PubMed ID: 21481991
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Identification of two small molecule inhibitors of hypoxia-inducible factor 1 with different cell-based screening model].
    Lang L; Tang K; Li Y; Liu X; Wang C; Chen X
    Zhongguo Zhong Yao Za Zhi; 2012 Jul; 37(14):2151-5. PubMed ID: 23126204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.
    Sun HL; Liu YN; Huang YT; Pan SL; Huang DY; Guh JH; Lee FY; Kuo SC; Teng CM
    Oncogene; 2007 Jun; 26(27):3941-51. PubMed ID: 17213816
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis of a novel 4-O-methylsaucerneol analogue LXY7824 as potent HIF-1 inhibitor and anti-cancer agent.
    Liu XY; Li XY; Yang FL; Li Y; Jiao XZ; Xie P
    J Asian Nat Prod Res; 2018 Jun; 20(6):545-558. PubMed ID: 29862843
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.