326 related articles for article (PubMed ID: 25143381)
1. Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor.
Liu X; Obianyo O; Chan CB; Huang J; Xue S; Yang JJ; Zeng F; Goodman M; Ye K
J Biol Chem; 2014 Oct; 289(40):27571-84. PubMed ID: 25143381
[TBL] [Abstract][Full Text] [Related]
2. Crosstalk between the muscular estrogen receptor α and BDNF/TrkB signaling alleviates metabolic syndrome via 7,8-dihydroxyflavone in female mice.
Zhao Z; Xue F; Gu Y; Han J; Jia Y; Ye K; Zhang Y
Mol Metab; 2021 Mar; 45():101149. PubMed ID: 33352311
[TBL] [Abstract][Full Text] [Related]
3. 7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways.
Tsai T; Klausmeyer A; Conrad R; Gottschling C; Leo M; Faissner A; Wiese S
Mol Cell Neurosci; 2013 Sep; 56():18-28. PubMed ID: 23500004
[TBL] [Abstract][Full Text] [Related]
4. 7,8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease.
Devi L; Ohno M
Neuropsychopharmacology; 2012 Jan; 37(2):434-44. PubMed ID: 21900882
[TBL] [Abstract][Full Text] [Related]
5. A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.
Jang SW; Liu X; Yepes M; Shepherd KR; Miller GW; Liu Y; Wilson WD; Xiao G; Blanchi B; Sun YE; Ye K
Proc Natl Acad Sci U S A; 2010 Feb; 107(6):2687-92. PubMed ID: 20133810
[TBL] [Abstract][Full Text] [Related]
6. 7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway.
García-Díaz Barriga G; Giralt A; Anglada-Huguet M; Gaja-Capdevila N; Orlandi JG; Soriano J; Canals JM; Alberch J
Hum Mol Genet; 2017 Aug; 26(16):3144-3160. PubMed ID: 28541476
[TBL] [Abstract][Full Text] [Related]
7. Activation of cardiac TrkB receptor by its small molecular agonist 7,8-dihydroxyflavone inhibits doxorubicin-induced cardiotoxicity via enhancing mitochondrial oxidative phosphorylation.
Zhao J; Du J; Pan Y; Chen T; Zhao L; Zhu Y; Chen Y; Zheng Y; Liu Y; Sun L; Hang P; Du Z
Free Radic Biol Med; 2019 Jan; 130():557-567. PubMed ID: 30472367
[TBL] [Abstract][Full Text] [Related]
8. A flavonoid agonist of the TrkB receptor for BDNF improves hippocampal neurogenesis and hippocampus-dependent memory in the Ts65Dn mouse model of DS.
Stagni F; Giacomini A; Guidi S; Emili M; Uguagliati B; Salvalai ME; Bortolotto V; Grilli M; Rimondini R; Bartesaghi R
Exp Neurol; 2017 Dec; 298(Pt A):79-96. PubMed ID: 28882412
[TBL] [Abstract][Full Text] [Related]
9. Exploring the Molecular Interactions of 7,8-Dihydroxyflavone and Its Derivatives with TrkB and VEGFR2 Proteins.
Chitranshi N; Gupta V; Kumar S; Graham SL
Int J Mol Sci; 2015 Sep; 16(9):21087-108. PubMed ID: 26404256
[TBL] [Abstract][Full Text] [Related]
10. Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death.
Ahmed S; Kwatra M; Gawali B; Panda SR; Naidu VGM
Apoptosis; 2021 Feb; 26(1-2):52-70. PubMed ID: 33226552
[TBL] [Abstract][Full Text] [Related]
11. Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease.
Jiang M; Peng Q; Liu X; Jin J; Hou Z; Zhang J; Mori S; Ross CA; Ye K; Duan W
Hum Mol Genet; 2013 Jun; 22(12):2462-70. PubMed ID: 23446639
[TBL] [Abstract][Full Text] [Related]
12. O-methylated metabolite of 7,8-dihydroxyflavone activates TrkB receptor and displays antidepressant activity.
Liu X; Qi Q; Xiao G; Li J; Luo HR; Ye K
Pharmacology; 2013; 91(3-4):185-200. PubMed ID: 23445871
[TBL] [Abstract][Full Text] [Related]
13. Flavonoid derivative 7,8-DHF attenuates TBI pathology via TrkB activation.
Agrawal R; Noble E; Tyagi E; Zhuang Y; Ying Z; Gomez-Pinilla F
Biochim Biophys Acta; 2015 May; 1852(5):862-72. PubMed ID: 25661191
[TBL] [Abstract][Full Text] [Related]
14. Supramolecular Nanostructure Activates TrkB Receptor Signaling of Neuronal Cells by Mimicking Brain-Derived Neurotrophic Factor.
Edelbrock AN; Àlvarez Z; Simkin D; Fyrner T; Chin SM; Sato K; Kiskinis E; Stupp SI
Nano Lett; 2018 Oct; 18(10):6237-6247. PubMed ID: 30211565
[TBL] [Abstract][Full Text] [Related]
15. Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway.
Zhong L; Luo F; Zhao W; Feng Y; Wu L; Lin J; Liu T; Wang S; You X; Zhang W
J Cell Mol Med; 2016 Oct; 20(10):1920-31. PubMed ID: 27297627
[TBL] [Abstract][Full Text] [Related]
16. Modulatory effects of the novel TrkB receptor agonist 7,8-dihydroxyflavone on synaptic transmission and intrinsic neuronal excitability in mouse visual cortex in vitro.
Marongiu D; Imbrosci B; Mittmann T
Eur J Pharmacol; 2013 Jun; 709(1-3):64-71. PubMed ID: 23567067
[TBL] [Abstract][Full Text] [Related]
17. Chronic TrkB agonist treatment in old age does not mitigate diaphragm neuromuscular dysfunction.
Greising SM; Vasdev AK; Zhan WZ; Sieck GC; Mantilla CB
Physiol Rep; 2017 Jan; 5(1):. PubMed ID: 28082429
[TBL] [Abstract][Full Text] [Related]
18. 7,8-Dihydroxyflavone protects retinal ganglion cells against chronic intermittent hypoxia-induced oxidative stress damage via activation of the BDNF/TrkB signaling pathway.
Fang YY; Luo M; Yue S; Han Y; Zhang HJ; Zhou YH; Liu K; Liu HG
Sleep Breath; 2022 Mar; 26(1):287-295. PubMed ID: 33993395
[TBL] [Abstract][Full Text] [Related]
19. Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist.
Shirayama Y; Yang C; Zhang JC; Ren Q; Yao W; Hashimoto K
Eur Neuropsychopharmacol; 2015 Dec; 25(12):2449-58. PubMed ID: 26419294
[TBL] [Abstract][Full Text] [Related]
20. Transepithelial transport mechanisms of 7,8-dihydroxyflavone, a small molecular TrkB receptor agonist, in human intestinal Caco-2 cells.
Chen Y; Xue F; Xia G; Zhao Z; Chen C; Li Y; Zhang Y
Food Funct; 2019 Aug; 10(8):5215-5227. PubMed ID: 31384856
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
