BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 25146045)

  • 1. The serine protease inhibitor TLCK attenuates intrinsic death pathways in neurons upstream of mitochondrial demise.
    Reuther C; Ganjam GK; Dolga AM; Culmsee C
    Apoptosis; 2014 Nov; 19(11):1545-58. PubMed ID: 25146045
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases.
    Frydrych I; Mlejnek P
    J Cell Biochem; 2008 Apr; 103(5):1646-56. PubMed ID: 17879947
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of TLCK-sensitive serine protease in colchicine-induced cell death of sympathetic neurons in culture.
    Mitsui C; Sakai K; Ninomiya T; Koike T
    J Neurosci Res; 2001 Nov; 66(4):601-11. PubMed ID: 11746380
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction.
    Rideout HJ; Zang E; Yeasmin M; Gordon R; Jabado O; Park DS; Stefanis L
    Neuroscience; 2001; 107(2):339-52. PubMed ID: 11731108
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BID links ferroptosis to mitochondrial cell death pathways.
    Neitemeier S; Jelinek A; Laino V; Hoffmann L; Eisenbach I; Eying R; Ganjam GK; Dolga AM; Oppermann S; Culmsee C
    Redox Biol; 2017 Aug; 12():558-570. PubMed ID: 28384611
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death.
    Grohm J; Plesnila N; Culmsee C
    Brain Behav Immun; 2010 Jul; 24(5):831-8. PubMed ID: 19961923
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) do not inhibit caspase-3 and caspase-7 processing in cells exposed to pro-apoptotic inducing stimuli.
    Frydrych I; Mlejnek P
    J Cell Biochem; 2008 Dec; 105(6):1501-6. PubMed ID: 18980241
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N-alpha-p-tosyl-L-lysine chloromethyl ketone (TLCK) suppresses neuritic degeneration caused by different experimental paradigms including in vitro Wallerian degeneration.
    Ikegami K; Kato S; Koike T
    Brain Res; 2004 Dec; 1030(1):81-93. PubMed ID: 15567340
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor.
    Grabarek J; Dragan M; Lee BW; Johnson GL; Darzynkiewicz Z
    Int J Oncol; 2002 Feb; 20(2):225-33. PubMed ID: 11788882
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The serine protease inhibitors, tosylphenylalanine chloromethyl ketone and tosyllysine chloromethyl ketone, potently inhibit pp70s6k activation.
    Grammer TC; Blenis J
    J Biol Chem; 1996 Sep; 271(39):23650-2. PubMed ID: 8798584
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A critical assessment of the effect of serine protease inhibitors on porcine fertilization and quality parameters of porcine spermatozoa in vitro.
    Beek J; Maes D; Nauwynck H; Piepers S; Van Soom A
    Reprod Biol; 2015 Mar; 15(1):9-19. PubMed ID: 25726372
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel N-phenyl-substituted thiazolidinediones protect neural cells against glutamate- and tBid-induced toxicity.
    Oppermann S; Schrader FC; Elsässer K; Dolga AM; Kraus AL; Doti N; Wegscheid-Gerlach C; Schlitzer M; Culmsee C
    J Pharmacol Exp Ther; 2014 Aug; 350(2):273-89. PubMed ID: 24849923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Can application of serine protease inhibitors TPCK and TLCK provide evidence for possible involvement of serine protease Omi/HtrA2 in imatinib mesylate-induced cell death of BCR-ABL-positive human leukemia cells?
    Mlejnek P
    Leukemia; 2005 Jun; 19(6):1085-7. PubMed ID: 15800674
    [No Abstract]   [Full Text] [Related]  

  • 14. Serine protease inhibitors interact with IFN-γ through up-regulation of FasR; a novel therapeutic strategy against cancer.
    Shadrin N; Shapira MG; Khalfin B; Uppalapati L; Parola AH; Nathan I
    Exp Cell Res; 2015 Jan; 330(2):233-239. PubMed ID: 25449698
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis.
    Movsesyan VA; Yakovlev AG; Fan L; Faden AI
    Exp Neurol; 2001 Feb; 167(2):366-75. PubMed ID: 11161625
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protease inhibitors protect macrophages from lipopolysaccharide-induced cytotoxicity: possible role for NF-kappaB.
    Abate A; Schröder H
    Life Sci; 1998; 62(12):1081-8. PubMed ID: 9519810
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitors of trypsin-like serine proteases inhibit processing of the caspase Nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support.
    Stefanis L; Troy CM; Qi H; Greene LA
    J Neurochem; 1997 Oct; 69(4):1425-37. PubMed ID: 9326271
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A role for serine proteases in mediating phorbol ester-induced differentiation of HL-60 cells.
    Bestilny LJ; Riabowol KT
    Exp Cell Res; 2000 Apr; 256(1):264-71. PubMed ID: 10739673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The serine protease inhibitors TLCK and TPCK inhibit the in vitro immortalization of primary human keratinocytes by HPV-18 DNA.
    Stöppler H; Koval D; Schlegel R
    Oncogene; 1996 Oct; 13(7):1545-8. PubMed ID: 8875993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ionizing radiation-induced, Bax-mediated cell death is dependent on activation of cysteine and serine proteases.
    Gong B; Chen Q; Endlich B; Mazumder S; Almasan A
    Cell Growth Differ; 1999 Jul; 10(7):491-502. PubMed ID: 10437917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.