BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 2514611)

  • 1. A method for the synchronization of cultured cells with aphidicolin: application to the large-scale synchronization of L1210 cells and the study of the cell cycle regulation of thymidylate synthase and dihydrofolate reductase.
    Matherly LH; Schuetz JD; Westin E; Goldman ID
    Anal Biochem; 1989 Nov; 182(2):338-45. PubMed ID: 2514611
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rate and extent of interconversion of tetrahydrofolate cofactors to dihydrofolate after cessation of dihydrofolate reductase activity in stationary versus log phase L1210 leukemia cells.
    Trent DF; Seither RL; Goldman ID
    J Biol Chem; 1991 Mar; 266(9):5445-9. PubMed ID: 1825999
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thymidylate synthase inhibition in cells with arrested DNA synthesis is not due to an allosteric interaction in the replitase complex.
    Rode W; Jastreboff MM; Bertino JR
    Biochem Biophys Res Commun; 1985 Apr; 128(1):345-51. PubMed ID: 3921023
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study.
    Jackman AL; Taylor GA; Gibson W; Kimbell R; Brown M; Calvert AH; Judson IR; Hughes LR
    Cancer Res; 1991 Oct; 51(20):5579-86. PubMed ID: 1913676
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interconversion of tetrahydrofolate cofactors to dihydrofolate induced by trimetrexate after suppression of thymidylate synthase by fluorodeoxyuridine in L1210 leukemia cells.
    Seither RL; Rape TJ; Goldman ID
    Biochem Pharmacol; 1992 Jun; 43(12):2647-54. PubMed ID: 1385949
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synchronization of HeLa cell cultures by inhibition of DNA polymerase alpha with aphidicolin.
    Pedrali-Noy G; Spadari S; Miller-Faurès A; Miller AO; Kruppa J; Koch G
    Nucleic Acids Res; 1980 Jan; 8(2):377-87. PubMed ID: 6775308
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetics of DNA replication in C3H 10T1/2 cells synchronized by aphidicolin.
    Cordeiro-Stone M; Kaufman DG
    Biochemistry; 1985 Aug; 24(18):4815-22. PubMed ID: 3935153
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
    FitzGerald GB; Wick MM
    Anticancer Drug Des; 1989 Jun; 4(1):79-87. PubMed ID: 2757754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Studies directed toward testing the "channeling" hypothesis--ribonucleotides----DNA in leukemia L1210 cells.
    Chiba P; Bacon PE; Cory JG
    Biochem Biophys Res Commun; 1984 Sep; 123(2):656-62. PubMed ID: 6435617
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular localization of dihydrofolate reductase-thymidylate synthase in carrot cells.
    Cella R; Balestrazzi A; Carbonera D; Nano R; Rezzani R
    Eur J Basic Appl Histochem; 1991; 35(1):61-71. PubMed ID: 1863664
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of thymidylate synthase gene amplification and of mRNA levels in the cell cycle.
    Imam AM; Crossley PH; Jackman AL; Little PF
    J Biol Chem; 1987 May; 262(15):7368-73. PubMed ID: 3584117
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
    Jackman AL; Alison DL; Calvert AH; Harrap KR
    Cancer Res; 1986 Jun; 46(6):2810-5. PubMed ID: 2938731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Study of dihydrofolate reductase-thymidylate synthase in Plasmodium falciparum.
    Inselburg J; Zhang RD
    Am J Trop Med Hyg; 1988 Oct; 39(4):328-36. PubMed ID: 3142285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL; McQueen CA; DeAngelis LM; Bertino JR
    Cancer Res; 1976 Jul; 36(7 PT 1):2442-9. PubMed ID: 1277151
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells.
    Bunni M; Doig MT; Donato H; Kesavan V; Priest DG
    Cancer Res; 1988 Jun; 48(12):3398-404. PubMed ID: 3370638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo.
    Kawai M; Hillcoat BL
    Cancer Res; 1974 Jul; 34(7):1619-26. PubMed ID: 4833915
    [No Abstract]   [Full Text] [Related]  

  • 17. Strategies for the measurement of the inhibitory effects of thymidine analogs on the activity of thymidylate synthase in intact murine leukemia L1210 cells.
    Balzarini J; De Clercq E
    Biochim Biophys Acta; 1984 Feb; 785(1-2):36-45. PubMed ID: 6696920
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A reversible arrest point in the late G1 phase of the mammalian cell cycle.
    Lalande M
    Exp Cell Res; 1990 Feb; 186(2):332-9. PubMed ID: 2153561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of thymidylate synthetase in mouse leukemia cells (L1210).
    Rode W; Scanlon KJ; Moroson BA; Bertino JR
    J Biol Chem; 1980 Feb; 255(4):1305-11. PubMed ID: 6965493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for a localized conversion of endogenous tetrahydrofolate cofactors to dihydrofolate as an important element in antifolate action in murine leukemia cells.
    Matherly LH; Muench SP
    Biochem Pharmacol; 1990 Jun; 39(12):2005-14. PubMed ID: 2141258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.