BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

386 related articles for article (PubMed ID: 25147206)

  • 1. Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.
    Reddy K; Schmidt MH; Geist JM; Thakkar NP; Panigrahi GB; Wang YH; Pearson CE
    Nucleic Acids Res; 2014; 42(16):10473-87. PubMed ID: 25147206
    [TBL] [Abstract][Full Text] [Related]  

  • 2. R loops stimulate genetic instability of CTG.CAG repeats.
    Lin Y; Dent SY; Wilson JH; Wells RD; Napierala M
    Proc Natl Acad Sci U S A; 2010 Jan; 107(2):692-7. PubMed ID: 20080737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disease-associated repeat instability and mismatch repair.
    Schmidt MHM; Pearson CE
    DNA Repair (Amst); 2016 Feb; 38():117-126. PubMed ID: 26774442
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats.
    Reddy K; Tam M; Bowater RP; Barber M; Tomlinson M; Nichol Edamura K; Wang YH; Pearson CE
    Nucleic Acids Res; 2011 Mar; 39(5):1749-62. PubMed ID: 21051337
    [TBL] [Abstract][Full Text] [Related]  

  • 5. R-loops: targets for nuclease cleavage and repeat instability.
    Freudenreich CH
    Curr Genet; 2018 Aug; 64(4):789-794. PubMed ID: 29327083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures.
    Reddy K; Zamiri B; Stanley SYR; Macgregor RB; Pearson CE
    J Biol Chem; 2013 Apr; 288(14):9860-9866. PubMed ID: 23423380
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RNA-DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication.
    Neil AJ; Liang MU; Khristich AN; Shah KA; Mirkin SM
    Nucleic Acids Res; 2018 Apr; 46(7):3487-3497. PubMed ID: 29447396
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins.
    Zamiri B; Reddy K; Macgregor RB; Pearson CE
    J Biol Chem; 2014 Feb; 289(8):4653-9. PubMed ID: 24371143
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner.
    Yang J; Freudenreich CH
    Gene; 2007 May; 393(1-2):110-5. PubMed ID: 17383831
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration.
    Wang J; Haeusler AR; Simko EA
    Cell Cycle; 2015; 14(4):526-32. PubMed ID: 25590632
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytosine deamination and base excision repair cause R-loop-induced CAG repeat fragility and instability in
    Su XA; Freudenreich CH
    Proc Natl Acad Sci U S A; 2017 Oct; 114(40):E8392-E8401. PubMed ID: 28923949
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks.
    Slean MM; Panigrahi GB; Castel AL; Pearson AB; Tomkinson AE; Pearson CE
    DNA Repair (Amst); 2016 Jun; 42():107-18. PubMed ID: 27155933
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia.
    LeProust EM; Pearson CE; Sinden RR; Gao X
    J Mol Biol; 2000 Oct; 302(5):1063-80. PubMed ID: 11183775
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New insights into repeat instability: role of RNA•DNA hybrids.
    McIvor EI; Polak U; Napierala M
    RNA Biol; 2010; 7(5):551-8. PubMed ID: 20729633
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Slipped (CTG).(CAG) repeats of the myotonic dystrophy locus: surface probing with anti-DNA antibodies.
    Tam M; Erin Montgomery S; Kekis M; Stollar BD; Price GB; Pearson CE
    J Mol Biol; 2003 Sep; 332(3):585-600. PubMed ID: 12963369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RNA FISH for detecting expanded repeats in human diseases.
    Urbanek MO; Krzyzosiak WJ
    Methods; 2016 Apr; 98():115-123. PubMed ID: 26615955
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy.
    Timchenko LT; Timchenko NA; Caskey CT; Roberts R
    Hum Mol Genet; 1996 Jan; 5(1):115-21. PubMed ID: 8789448
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
    Almeida S; Gascon E; Tran H; Chou HJ; Gendron TF; Degroot S; Tapper AR; Sellier C; Charlet-Berguerand N; Karydas A; Seeley WW; Boxer AL; Petrucelli L; Miller BL; Gao FB
    Acta Neuropathol; 2013 Sep; 126(3):385-99. PubMed ID: 23836290
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The G-rich Repeats in
    Abu Diab M; Mor-Shaked H; Cohen E; Cohen-Hadad Y; Ram O; Epsztejn-Litman S; Eiges R
    Genetics; 2018 Dec; 210(4):1239-1252. PubMed ID: 30396881
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FAN1 exo- not endo-nuclease pausing on disease-associated slipped-DNA repeats: A mechanism of repeat instability.
    Deshmukh AL; Caron MC; Mohiuddin M; Lanni S; Panigrahi GB; Khan M; Engchuan W; Shum N; Faruqui A; Wang P; Yuen RKC; Nakamori M; Nakatani K; Masson JY; Pearson CE
    Cell Rep; 2021 Dec; 37(10):110078. PubMed ID: 34879276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.