These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 25163632)

  • 1. Functional characterization of a new human melanocortin-4 receptor homozygous mutation (N72K) that is associated with early-onset obesity.
    Delhanty PJ; Bouw E; Huisman M; Vervenne RM; Themmen AP; van der Lely AJ; van den Akker EL
    Mol Biol Rep; 2014 Dec; 41(12):7967-72. PubMed ID: 25163632
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Novel Loss of Function Melanocortin-4-Receptor Mutation (MC4R-F313Sfs*29) in Morbid Obesity.
    Trevellin E; Granzotto M; Host C; Grisan F; De Stefani D; Grinzato A; Lefkimmiatis K; Pagano C; Rizzuto R; Vettor R
    J Clin Endocrinol Metab; 2021 Mar; 106(3):736-749. PubMed ID: 33247923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Point mutations in the melanocortin-4 receptor cause variable obesity in mice.
    Meehan TP; Tabeta K; Du X; Woodward LS; Firozi K; Beutler B; Justice MJ
    Mamm Genome; 2006 Dec; 17(12):1162-71. PubMed ID: 17143585
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intracellular retention of human melanocortin-4 receptor: a molecular mechanism underlying early-onset obesity in F261S pedigree of Chinese.
    Fang QC; Jia WP; Cai SB; Shao XY; Zhang R; Wang CR; Bao YQ; Xiang KS
    Biomed Environ Sci; 2008 Aug; 21(4):280-5. PubMed ID: 18837289
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity.
    Niazi RK; Gjesing AP; Hollensted M; Have CT; Grarup N; Pedersen O; Ullah A; Shahid G; Ahmad W; Gul A; Hansen T
    BMC Med Genet; 2018 Nov; 19(1):199. PubMed ID: 30442103
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Novel homozygous missense mutation of melanocortin-4 receptor (MC4R) in a Japanese woman with severe obesity.
    Kobayashi H; Ogawa Y; Shintani M; Ebihara K; Shimodahira M; Iwakura T; Hino M; Ishihara T; Ikekubo K; Kurahachi H; Nakao K
    Diabetes; 2002 Jan; 51(1):243-6. PubMed ID: 11756348
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel non-synonymous mutation in the melanocortin-4 receptor gene (MC4R) in a 2-year-old Austrian girl with extreme obesity.
    Rettenbacher E; Tarnow P; Brumm H; Prayer D; Wermter AK; Hebebrand J; Biebermann H; Hinney A; Widhalm K
    Exp Clin Endocrinol Diabetes; 2007 Jan; 115(1):7-12. PubMed ID: 17286227
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional Characterization of Novel
    Mohammed I; Selvaraj S; Ahmed WS; Al-Barazenji T; Hammad AS; Dauleh H; Saraiva LR; Al-Shafai M; Hussain K
    Int J Mol Sci; 2023 Nov; 24(22):. PubMed ID: 38003551
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel MC4R deletion coexisting with FTO and MC1R gene variants, causes severe early onset obesity.
    Neocleous V; Shammas C; Phelan MM; Fanis P; Pantelidou M; Skordis N; Mantzoros C; Phylactou LA; Toumba M
    Hormones (Athens); 2016 Jul; 15(3):445-452. PubMed ID: 27394708
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MC4R Variants Modulate α-MSH and Setmelanotide Induced Cellular Signaling at Multiple Levels.
    Rodríguez Rondón AV; Welling MS; van den Akker ELT; van Rossum EFC; Boon EMJ; van Haelst MM; Delhanty PJD; Visser JA
    J Clin Endocrinol Metab; 2024 Sep; 109(10):2452-2466. PubMed ID: 38567654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heterozygous versus homozygous phenotype caused by the same MC4R mutation: novel mutation affecting a large consanguineous kindred.
    Drabkin M; Birk OS; Birk R
    BMC Med Genet; 2018 Aug; 19(1):135. PubMed ID: 30068297
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Homozygous null mutation of the melanocortin-4 receptor and severe early-onset obesity.
    Dubern B; Bisbis S; Talbaoui H; Le Beyec J; Tounian P; Lacorte JM; Clément K
    J Pediatr; 2007 Jun; 150(6):613-7, 617.e1. PubMed ID: 17517245
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signal pathway analysis of selected obesity-associated melanocortin-4 receptor class V mutants.
    Sharma S; Thibodeau S; Lytton J
    Biochim Biophys Acta Mol Basis Dis; 2020 Aug; 1866(8):165835. PubMed ID: 32423884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.
    Ayers KL; Glicksberg BS; Garfield AS; Longerich S; White JA; Yang P; Du L; Chittenden TW; Gulcher JR; Roy S; Fiedorek F; Gottesdiener K; Cohen S; North KE; Schadt EE; Li SD; Chen R; Van der Ploeg LHT
    J Clin Endocrinol Metab; 2018 Jul; 103(7):2601-2612. PubMed ID: 29726959
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rescue of defective MC4R cell-surface expression and signaling by a novel pharmacoperone Ipsen 17.
    Wang XH; Wang HM; Zhao BL; Yu P; Fan ZC
    J Mol Endocrinol; 2014 Aug; 53(1):17-29. PubMed ID: 24780838
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional alterations of two novel MC4R mutations found in Argentinian pediatric patients with early onset obesity.
    Fernández E; McCarthy CI; Cerviño RH; Rodríguez SS; Yaneff A; Hernández J; Garrido V; Di Rocco F; Raingo J
    Mol Cell Endocrinol; 2023 Jan; 559():111777. PubMed ID: 36210601
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity.
    René P; Le Gouill C; Pogozheva ID; Lee G; Mosberg HI; Farooqi IS; Valenzano KJ; Bouvier M
    J Pharmacol Exp Ther; 2010 Dec; 335(3):520-32. PubMed ID: 20826565
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Melanocortin pathways: suppressed and stimulated melanocortin-4 receptor (MC4R).
    Hainer V; Aldhoon Hainerová I; Kunešová M; Taxová Braunerová R; Zamrazilová H; Bendlová B
    Physiol Res; 2020 Sep; 69(Suppl 2):S245-S254. PubMed ID: 33094623
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CRTC1 deficiency, specifically in melanocortin-4 receptor-expressing cells, induces hyperphagia, obesity, and insulin resistance.
    Matsumura S; Miyakita M; Miyamori H; Kyo S; Ishikawa F; Sasaki T; Jinno T; Tanaka J; Fujita K; Yokokawa T; Goto T; Momma K; Takenaka S; Inoue K
    FASEB J; 2022 Dec; 36(12):e22645. PubMed ID: 36349991
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacological chaperone action in humanized mouse models of MC4R-linked obesity.
    René P; Lanfray D; Richard D; Bouvier M
    JCI Insight; 2021 Feb; 6(4):. PubMed ID: 33434184
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.