BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 25165877)

  • 1. Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway.
    Milosch N; Tanriöver G; Kundu A; Rami A; François JC; Baumkötter F; Weyer SW; Samanta A; Jäschke A; Brod F; Buchholz CJ; Kins S; Behl C; Müller UC; Kögel D
    Cell Death Dis; 2014 Aug; 5(8):e1391. PubMed ID: 25165877
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation.
    Zhang SQ; Sawmiller D; Li S; Rezai-Zadeh K; Hou H; Zhou S; Shytle D; Giunta B; Fernandez F; Mori T; Tan J
    PLoS One; 2013; 8(8):e71913. PubMed ID: 23977176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of BAG3 Expression and Proteasomal Activity by sAPPα Does Not Require Membrane-Tethered Holo-APP.
    Kundu A; Milosch N; Antonietti P; Baumkötter F; Zymny A; Müller UC; Kins S; Hajieva P; Behl C; Kögel D
    Mol Neurobiol; 2016 Nov; 53(9):5985-5994. PubMed ID: 26526841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor protein.
    Delarasse C; Auger R; Gonnord P; Fontaine B; Kanellopoulos JM
    J Biol Chem; 2011 Jan; 286(4):2596-606. PubMed ID: 21081501
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of amyloid precursor protein processing enhances gemcitabine-mediated cytotoxicity in pancreatic cancer cells.
    Woods NK; Padmanabhan J
    J Biol Chem; 2013 Oct; 288(42):30114-30124. PubMed ID: 24022491
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin-like growth factor-1 (IGF-1)-induced processing of amyloid-beta precursor protein (APP) and APP-like protein 2 is mediated by different metalloproteinases.
    Jacobsen KT; Adlerz L; Multhaup G; Iverfeldt K
    J Biol Chem; 2010 Apr; 285(14):10223-31. PubMed ID: 20139073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Surface expression and limited proteolysis of ADAM10 are increased by a dominant negative inhibitor of dynamin.
    Carey RM; Blusztajn JK; Slack BE
    BMC Cell Biol; 2011 May; 12():20. PubMed ID: 21586144
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-1alpha stimulates non-amyloidogenic pathway by alpha-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase.
    Bandyopadhyay S; Hartley DM; Cahill CM; Lahiri DK; Chattopadhyay N; Rogers JT
    J Neurosci Res; 2006 Jul; 84(1):106-18. PubMed ID: 16724341
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways.
    Webster NJ; Green KN; Settle VJ; Peers C; Vaughan PF
    Brain Res Mol Brain Res; 2004 Nov; 130(1-2):161-9. PubMed ID: 15519686
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hydrogen sulfide-induced processing of the amyloid precursor protein in SH-SY5Y human neuroblastoma cells involves the PI3-K/Akt signaling pathway.
    Zhang H; Gao Y; Zhao FL; Qiao PF; Yan Y
    Cell Mol Neurobiol; 2015 Mar; 35(2):265-72. PubMed ID: 25293506
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress.
    Clement AB; Hanstein R; Schröder A; Nagel H; Endres K; Fahrenholz F; Behl C
    Neuroscience; 2008 Mar; 152(2):459-68. PubMed ID: 18276079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.
    Hogl S; Kuhn PH; Colombo A; Lichtenthaler SF
    PLoS One; 2011; 6(6):e21337. PubMed ID: 21695060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cryptotanshinione upregulates alpha-secretase by activation PI3K pathway in cortical neurons.
    Mei Z; Situ B; Tan X; Zheng S; Zhang F; Yan P; Liu P
    Brain Res; 2010 Aug; 1348():165-73. PubMed ID: 20595051
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin.
    Demars MP; Bartholomew A; Strakova Z; Lazarov O
    Stem Cell Res Ther; 2011 Aug; 2(4):36. PubMed ID: 21878106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt.
    Shi C; Zheng DD; Fang L; Wu F; Kwong WH; Xu J
    Biochim Biophys Acta; 2012 Apr; 1820(4):453-60. PubMed ID: 22178929
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein.
    Cheng G; Yu Z; Zhou D; Mattson MP
    Exp Neurol; 2002 Jun; 175(2):407-14. PubMed ID: 12061870
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancer.
    Tsang JYS; Lee MA; Chan TH; Li J; Ni YB; Shao Y; Chan SK; Cheungc SY; Lau KF; Tse GMK
    EBioMedicine; 2018 Dec; 38():89-99. PubMed ID: 30470613
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.
    Corbett GT; Gonzalez FJ; Pahan K
    Proc Natl Acad Sci U S A; 2015 Jul; 112(27):8445-50. PubMed ID: 26080426
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B; Crawford F; Bachmeier C
    Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.
    Colombo A; Wang H; Kuhn PH; Page R; Kremmer E; Dempsey PJ; Crawford HC; Lichtenthaler SF
    Neurobiol Dis; 2013 Jan; 49():137-47. PubMed ID: 22940630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.