These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 25168029)

  • 41. Transformation of acetaminophen by chlorination produces the toxicants 1,4-benzoquinone and N-acetyl-p-benzoquinone imine.
    Bedner M; MacCrehan WA
    Environ Sci Technol; 2006 Jan; 40(2):516-22. PubMed ID: 16468397
    [TBL] [Abstract][Full Text] [Related]  

  • 42. A novel and cost effective method of removing excess albumin from plasma/serum samples and its impacts on LC-MS/MS bioanalysis of therapeutic proteins.
    Liu G; Zhao Y; Angeles A; Hamuro LL; Arnold ME; Shen JX
    Anal Chem; 2014 Aug; 86(16):8336-43. PubMed ID: 25083595
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Covalent protein modification by reactive drug metabolites using online electrochemistry/liquid chromatography/mass spectrometry.
    Lohmann W; Hayen H; Karst U
    Anal Chem; 2008 Dec; 80(24):9714-9. PubMed ID: 19006340
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Effects of acetaminophen on the ultrastructure of isolated rat hepatocytes.
    Fujimura H; Kawasaki N; Tanimoto T; Sasaki H; Suzuki T
    Exp Toxicol Pathol; 1995 Nov; 47(5):345-51. PubMed ID: 8871066
    [TBL] [Abstract][Full Text] [Related]  

  • 45. High-throughput quantitation of amino acids in rat and mouse biological matrices using stable isotope labeling and UPLC-MS/MS analysis.
    Takach E; O'Shea T; Liu H
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Aug; 964():180-90. PubMed ID: 24842860
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxyparacetamol.
    Holme JA; Dahlin DC; Nelson SD; Dybing E
    Biochem Pharmacol; 1984 Feb; 33(3):401-6. PubMed ID: 6704159
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Glutathione S-transferase pi trapping method for generation and characterization of drug-protein adducts in human liver microsomes using liquid chromatography-tandem mass spectrometry.
    Yukinaga H; Iwabuchi H; Okazaki O; Izumi T
    J Pharm Biomed Anal; 2012; 67-68():186-92. PubMed ID: 22608530
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Acetaminophen-induced hepatotoxicity. Analysis of total covalent binding vs. specific binding to cysteine.
    Matthews AM; Roberts DW; Hinson JA; Pumford NR
    Drug Metab Dispos; 1996 Nov; 24(11):1192-6. PubMed ID: 8937852
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Nontargeted Identification of Reactive Metabolite Protein Adducts.
    Leeming MG; Donald WA; O'Hair RAJ
    Anal Chem; 2017 Jun; 89(11):5748-5756. PubMed ID: 28481086
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The
    Hashemi SA; Kyani A; Bathaie SZ
    J Biomol Struct Dyn; 2022 Nov; 40(18):8274-8285. PubMed ID: 33879035
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Mechanism of acetaminophen-induced hepatotoxicity: covalent binding versus oxidative stress.
    Gibson JD; Pumford NR; Samokyszyn VM; Hinson JA
    Chem Res Toxicol; 1996; 9(3):580-5. PubMed ID: 8728501
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Mass spectrometric strategies for the identification and characterization of human serum albumin covalently adducted by amoxicillin: ex vivo studies.
    Garzon D; Ariza A; Regazzoni L; Clerici R; Altomare A; Sirtori FR; Carini M; Torres MJ; PĂ©rez-Sala D; Aldini G
    Chem Res Toxicol; 2014 Sep; 27(9):1566-74. PubMed ID: 25088930
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Rat liver ADP-ribose pyrophosphatase-I as an in vitro target of the acetaminophen metabolite N-acetyl-p-benzoquinoneimine.
    Ribeiro JM; Agudo A; Costas MJ; Cameselle JC
    Biochim Biophys Acta; 1997 Oct; 1336(3):403-8. PubMed ID: 9367167
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Online 2D-LC-MS/MS assay to quantify therapeutic protein in human serum in the presence of pre-existing antidrug antibodies.
    Shen Y; Zhang G; Yang J; Qiu Y; McCauley T; Pan L; Wu J
    Anal Chem; 2015 Aug; 87(16):8555-63. PubMed ID: 26237058
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Identification of Acetaminophen Adducts of Rat Liver Microsomal Proteins using 2D-LC-MS/MS.
    Golizeh M; LeBlanc A; Sleno L
    Chem Res Toxicol; 2015 Nov; 28(11):2142-50. PubMed ID: 26510387
    [TBL] [Abstract][Full Text] [Related]  

  • 56. The metabolism of N-acetyl-3,5-dimethyl-p-benzoquinone imine in isolated hepatocytes involves N-deacetylation.
    Rossi L; McGirr LG; Silva J; O'Brien PJ
    Mol Pharmacol; 1988 Nov; 34(5):674-81. PubMed ID: 3193958
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Covalent binding of organophosphorothioates to albumin: a new perspective for OP-pesticide biomonitoring?
    Noort D; Hulst AG; van Zuylen A; van Rijssel E; van der Schans MJ
    Arch Toxicol; 2009 Nov; 83(11):1031-6. PubMed ID: 19575182
    [TBL] [Abstract][Full Text] [Related]  

  • 58. LC-MS/MS and GC-MS/MS measurement of plasma and urine di-paracetamol and 3-nitro-paracetamol: proof-of-concept studies on a novel human model of oxidative stress based on oral paracetamol administration.
    Trettin A; Modun D; Madunic S; Vukovic J; Radman M; Batkai S; Thum T; Jordan J; Tsikas D
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 May; 959():71-81. PubMed ID: 24768921
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen.
    Dong H; Haining RL; Thummel KE; Rettie AE; Nelson SD
    Drug Metab Dispos; 2000 Dec; 28(12):1397-400. PubMed ID: 11095574
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.
    Henderson CJ; Wolf CR; Kitteringham N; Powell H; Otto D; Park BK
    Proc Natl Acad Sci U S A; 2000 Nov; 97(23):12741-5. PubMed ID: 11058152
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.