453 related articles for article (PubMed ID: 25170081)
21. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR).
Strachan RT; Sun JP; Rominger DH; Violin JD; Ahn S; Rojas Bie Thomsen A; Zhu X; Kleist A; Costa T; Lefkowitz RJ
J Biol Chem; 2014 May; 289(20):14211-24. PubMed ID: 24668815
[TBL] [Abstract][Full Text] [Related]
22. beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress.
Rakesh K; Yoo B; Kim IM; Salazar N; Kim KS; Rockman HA
Sci Signal; 2010 Jun; 3(125):ra46. PubMed ID: 20530803
[TBL] [Abstract][Full Text] [Related]
23. Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2.
Wei H; Ahn S; Barnes WG; Lefkowitz RJ
J Biol Chem; 2004 Nov; 279(46):48255-61. PubMed ID: 15355986
[TBL] [Abstract][Full Text] [Related]
24. Nanobody-Mediated Dualsteric Engagement of the Angiotensin Receptor Broadens Biased Ligand Pharmacology.
Braga Emidio N; Small BM; Keller AR; Cheloha RW; Wingler LM
Mol Pharmacol; 2024 Feb; 105(3):260-271. PubMed ID: 38164609
[TBL] [Abstract][Full Text] [Related]
25. Angiotensin II cyclic analogs as tools to investigate AT
St-Pierre D; Cabana J; Holleran BJ; Besserer-Offroy É; Escher E; Guillemette G; Lavigne P; Leduc R
Biochem Pharmacol; 2018 Aug; 154():104-117. PubMed ID: 29684376
[TBL] [Abstract][Full Text] [Related]
26. β-Arrestin-mediated Angiotensin II Signaling Controls the Activation of ARF6 Protein and Endocytosis in Migration of Vascular Smooth Muscle Cells.
Charles R; Namkung Y; Cotton M; Laporte SA; Claing A
J Biol Chem; 2016 Feb; 291(8):3967-81. PubMed ID: 26703465
[TBL] [Abstract][Full Text] [Related]
27. Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR.
Wingler LM; Skiba MA; McMahon C; Staus DP; Kleinhenz ALW; Suomivuori CM; Latorraca NR; Dror RO; Lefkowitz RJ; Kruse AC
Science; 2020 Feb; 367(6480):888-892. PubMed ID: 32079768
[TBL] [Abstract][Full Text] [Related]
28. β-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis.
Wang Y; Huang J; Liu X; Niu Y; Zhao L; Yu Y; Zhou L; Lu L; Yu C
Am J Physiol Renal Physiol; 2017 Jul; 313(1):F1-F8. PubMed ID: 28274926
[TBL] [Abstract][Full Text] [Related]
29. Single-molecule force spectroscopy study of interactions between angiotensin II type 1 receptor and different biased ligands in living cells.
Li W; Xu J; Kou X; Zhao R; Zhou W; Fang X
Anal Bioanal Chem; 2018 May; 410(14):3275-3284. PubMed ID: 29492619
[TBL] [Abstract][Full Text] [Related]
30. Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis.
Kendall RT; Lee MH; Pleasant DL; Robinson K; Kuppuswamy D; McDermott PJ; Luttrell LM
J Biol Chem; 2014 Sep; 289(38):26155-26166. PubMed ID: 25081544
[TBL] [Abstract][Full Text] [Related]
31. Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor.
Gagnon L; Cao Y; Cho A; Sedki D; Huber T; Sakmar TP; Laporte SA
J Biol Chem; 2019 Nov; 294(46):17409-17420. PubMed ID: 31530642
[TBL] [Abstract][Full Text] [Related]
32. Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes.
Shenoy SK; Lefkowitz RJ
J Biol Chem; 2005 Apr; 280(15):15315-24. PubMed ID: 15699045
[TBL] [Abstract][Full Text] [Related]
33. Proximal tubule NHE3 activity is inhibited by beta-arrestin-biased angiotensin II type 1 receptor signaling.
Carneiro de Morais CP; Polidoro JZ; Ralph DL; Pessoa TD; Oliveira-Souza M; Barauna VG; Rebouças NA; Malnic G; McDonough AA; Girardi AC
Am J Physiol Cell Physiol; 2015 Oct; 309(8):C541-50. PubMed ID: 26246427
[TBL] [Abstract][Full Text] [Related]
34. Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors.
Pironti G; Strachan RT; Abraham D; Mon-Wei Yu S; Chen M; Chen W; Hanada K; Mao L; Watson LJ; Rockman HA
Circulation; 2015 Jun; 131(24):2120-30. PubMed ID: 25995315
[TBL] [Abstract][Full Text] [Related]
35. Cardiovascular angiotensin II type 1 receptor biased signaling: Focus on non-Gq-, non-βarrestin-dependent signaling.
Lymperopoulos A; Borges JI; Carbone AM; Cora N; Sizova A
Pharmacol Res; 2021 Dec; 174():105943. PubMed ID: 34662735
[TBL] [Abstract][Full Text] [Related]
36. β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1.
Mancini AD; Bertrand G; Vivot K; Carpentier É; Tremblay C; Ghislain J; Bouvier M; Poitout V
J Biol Chem; 2015 Aug; 290(34):21131-21140. PubMed ID: 26157145
[TBL] [Abstract][Full Text] [Related]
37. The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
Wilson PC; Lee MH; Appleton KM; El-Shewy HM; Morinelli TA; Peterson YK; Luttrell LM; Jaffa AA
J Biol Chem; 2013 Jun; 288(26):18872-84. PubMed ID: 23661707
[TBL] [Abstract][Full Text] [Related]
38. Mapping Angiotensin II Type 1 Receptor-Biased Signaling Using Proximity Labeling and Proteomics Identifies Diverse Actions of Biased Agonists.
Pfeiffer CT; Wang J; Paulo JA; Jiang X; Gygi SP; Rockman HA
J Proteome Res; 2021 Jun; 20(6):3256-3267. PubMed ID: 33950683
[TBL] [Abstract][Full Text] [Related]
39. The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network.
Kendall RT; Strungs EG; Rachidi SM; Lee MH; El-Shewy HM; Luttrell DK; Janech MG; Luttrell LM
J Biol Chem; 2011 Jun; 286(22):19880-91. PubMed ID: 21502318
[TBL] [Abstract][Full Text] [Related]
40. The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium.
Monasky MM; Taglieri DM; Henze M; Warren CM; Utter MS; Soergel DG; Violin JD; Solaro RJ
Am J Physiol Heart Circ Physiol; 2013 Sep; 305(6):H856-66. PubMed ID: 23873795
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
