216 related articles for article (PubMed ID: 25170083)
1. Catalytic activities of Werner protein are affected by adduction with 4-hydroxy-2-nonenal.
Czerwińska J; Poznański J; Dębski J; Bukowy Z; Bohr VA; Tudek B; Speina E
Nucleic Acids Res; 2014; 42(17):11119-35. PubMed ID: 25170083
[TBL] [Abstract][Full Text] [Related]
2. DNA binding residues in the RQC domain of Werner protein are critical for its catalytic activities.
Tadokoro T; Kulikowicz T; Dawut L; Croteau DL; Bohr VA
Aging (Albany NY); 2012 Jun; 4(6):417-29. PubMed ID: 22713343
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.
Aggarwal M; Sommers JA; Shoemaker RH; Brosh RM
Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1525-30. PubMed ID: 21220316
[TBL] [Abstract][Full Text] [Related]
4. Intrinsic ssDNA annealing activity in the C-terminal region of WRN.
Muftuoglu M; Kulikowicz T; Beck G; Lee JW; Piotrowski J; Bohr VA
Biochemistry; 2008 Sep; 47(39):10247-54. PubMed ID: 18771289
[TBL] [Abstract][Full Text] [Related]
5. Enzymatic mechanism of the WRN helicase/nuclease.
Brosh RM; Opresko PL; Bohr VA
Methods Enzymol; 2006; 409():52-85. PubMed ID: 16793395
[TBL] [Abstract][Full Text] [Related]
6. Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains.
Machwe A; Xiao L; Orren DK
BMC Mol Biol; 2006 Feb; 7():6. PubMed ID: 16503984
[TBL] [Abstract][Full Text] [Related]
7. DNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonuclease.
Ahn B; Bohr VA
Biochem Biophys Res Commun; 2011 Aug; 411(4):684-9. PubMed ID: 21763283
[TBL] [Abstract][Full Text] [Related]
8. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
Aggarwal M; Brosh RM
Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
[TBL] [Abstract][Full Text] [Related]
9. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
[TBL] [Abstract][Full Text] [Related]
10. Replication fork regression in vitro by the Werner syndrome protein (WRN): holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity.
Machwe A; Xiao L; Lloyd RG; Bolt E; Orren DK
Nucleic Acids Res; 2007; 35(17):5729-47. PubMed ID: 17717003
[TBL] [Abstract][Full Text] [Related]
11. Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions.
Popp O; Veith S; Fahrer J; Bohr VA; Bürkle A; Mangerich A
ACS Chem Biol; 2013 Jan; 8(1):179-88. PubMed ID: 23082994
[TBL] [Abstract][Full Text] [Related]
12. Molecular cooperation between the Werner syndrome protein and replication protein A in relation to replication fork blockage.
Machwe A; Lozada E; Wold MS; Li GM; Orren DK
J Biol Chem; 2011 Feb; 286(5):3497-508. PubMed ID: 21107010
[TBL] [Abstract][Full Text] [Related]
13. Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity.
Li B; Reddy S; Comai L
Aging (Albany NY); 2009 Mar; 1(3):289-302. PubMed ID: 20157518
[TBL] [Abstract][Full Text] [Related]
14. Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.
von Kobbe C; Harrigan JA; Schreiber V; Stiegler P; Piotrowski J; Dawut L; Bohr VA
Nucleic Acids Res; 2004; 32(13):4003-14. PubMed ID: 15292449
[TBL] [Abstract][Full Text] [Related]
15. WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand.
Bukowy Z; Harrigan JA; Ramsden DA; Tudek B; Bohr VA; Stevnsner T
Nucleic Acids Res; 2008 Sep; 36(15):4975-87. PubMed ID: 18658245
[TBL] [Abstract][Full Text] [Related]
16. Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.
Perry JJ; Asaithamby A; Barnebey A; Kiamanesch F; Chen DJ; Han S; Tainer JA; Yannone SM
J Biol Chem; 2010 Aug; 285(33):25699-707. PubMed ID: 20516064
[TBL] [Abstract][Full Text] [Related]
17. The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δ.
Kamath-Loeb AS; Shen JC; Schmitt MW; Loeb LA
J Biol Chem; 2012 Apr; 287(15):12480-90. PubMed ID: 22351772
[TBL] [Abstract][Full Text] [Related]
18. Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
Opresko PL; Laine JP; Brosh RM; Seidman MM; Bohr VA
J Biol Chem; 2001 Nov; 276(48):44677-87. PubMed ID: 11572872
[TBL] [Abstract][Full Text] [Related]
19. Roles of the Werner syndrome RecQ helicase in DNA replication.
Sidorova JM
DNA Repair (Amst); 2008 Nov; 7(11):1776-86. PubMed ID: 18722555
[TBL] [Abstract][Full Text] [Related]
20. Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein.
Choudhary S; Sommers JA; Brosh RM
J Biol Chem; 2004 Aug; 279(33):34603-13. PubMed ID: 15187093
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
