BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 25172146)

  • 1. Flexible, polymer-supported synthesis of sphingosine derivatives provides ceramides with enhanced biological activity.
    El-Dahshan A; Al-Gharabli SI; Radetzki S; Al-Tel TH; Kumar P; Rademann J
    Bioorg Med Chem; 2014 Oct; 22(19):5506-12. PubMed ID: 25172146
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and potent antileukemic activities of N-lactylsphingosine and N-lactyldihydrosphingosine.
    Azuma H; Takao R; Shikata K; Niiro H; Tachibana T; Ogino K
    J Med Chem; 2003 Jul; 46(16):3445-7. PubMed ID: 12877580
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and growth inhibitory activity of chiral 5-hydroxy-2-N-acyl-(3E)-sphingenines: ceramides with an unusual sphingoid backbone.
    Chun J; Byun HS; Arthur G; Bittman R
    J Org Chem; 2003 Jan; 68(2):355-9. PubMed ID: 12530860
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological activity of a family of novel ceramide analogues in chemoresistant breast cancer cells.
    Antoon JW; Liu J; Gestaut MM; Burow ME; Beckman BS; Foroozesh M
    J Med Chem; 2009 Sep; 52(18):5748-52. PubMed ID: 19694470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anticancer activity of a ceramide analog containing a disulfide linkage.
    Bittman R; Li Z; Samadder P; Arthur G
    Cancer Lett; 2007 Jun; 251(1):53-8. PubMed ID: 17141948
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sphingosine kinase 2 inhibitor SG-12 induces apoptosis via phosphorylation by sphingosine kinase 2.
    Hara-Yokoyama M; Terasawa K; Ichinose S; Watanabe A; Podyma-Inoue KA; Akiyoshi K; Igarashi Y; Yanagishita M
    Bioorg Med Chem Lett; 2013 Apr; 23(7):2220-4. PubMed ID: 23434415
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of a novel ceramide analogue via Tebbe methylenation and evaluation of its antiproliferative activity.
    Lu X; Arthur G; Bittman R
    Org Lett; 2005 Apr; 7(8):1645-8. PubMed ID: 15816773
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidase.
    Usta J; El Bawab S; Roddy P; Szulc ZM; Yusuf ; Hannun A; Bielawska A
    Biochemistry; 2001 Aug; 40(32):9657-68. PubMed ID: 11583166
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Straightforward access to spisulosine and 4,5-dehydrospisulosine stereoisomers: probes for profiling ceramide synthase activities in intact cells.
    Abad JL; Nieves I; Rayo P; Casas J; Fabriàs G; Delgado A
    J Org Chem; 2013 Jun; 78(12):5858-66. PubMed ID: 23679346
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
    Antoon JW; Beckman BS
    Bioorg Med Chem Lett; 2012 Apr; 22(7):2624-8. PubMed ID: 22366655
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate.
    Nussbaumer P; Hornillos V; Ghobrial M; Ullrich T
    Chem Phys Lipids; 2008 Feb; 151(2):125-8. PubMed ID: 18039471
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel jaspine B-ceramide hybrid modulates sphingolipid metabolism.
    Garcia V; Le Faouder P; Dupuy A; Levade T; Ballereau S; Génisson Y
    Chem Biodivers; 2015 Jul; 12(7):1115-25. PubMed ID: 26172331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel D: -erythro N-octanoyl sphingosine analogs as chemo- and endocrine-resistant breast cancer therapeutics.
    Antoon JW; Liu J; Ponnapakkam AP; Gestaut MM; Foroozesh M; Beckman BS
    Cancer Chemother Pharmacol; 2010 May; 65(6):1191-5. PubMed ID: 20155475
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of chiral hydroxylated enones as potential anti-tumor agents.
    Shing TK; Wu HT; Kwok HF; Lau CB
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7562-5. PubMed ID: 23102892
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of 2-epi-jaspine B analogs as selective sphingosine kinase 1 inhibitors.
    Yang H; Li Y; Chai H; Yakura T; Liu B; Yao Q
    Bioorg Chem; 2020 May; 98():103369. PubMed ID: 31703810
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of 7-oxasphingosine and -ceramide analogues and their evaluation in a model for apoptosis.
    Rajan R; Wallimann K; Vasella A; Pace D; Genazzani AA; Canonico PL; Condorelli F
    Chem Biodivers; 2004 Nov; 1(11):1785-99. PubMed ID: 17191816
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives.
    Fu W; Wang J; Yu L; Zhao L; Lu N; You Q; Guo Q; Li Z
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1118-21. PubMed ID: 22196122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sphingolipid metabolic changes during chiral C2-ceramides induced apoptosis in human leukemia cells.
    Baek MY; Yoo HS; Nakaya K; Moon DC; Lee YM
    Arch Pharm Res; 2001 Apr; 24(2):144-9. PubMed ID: 11339634
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Apoptotic activities of C2-ceramide and C2-dihydroceramide homologues against HL-60 cells.
    Shikata K; Niiro H; Azuma H; Ogino K; Tachibana T
    Bioorg Med Chem; 2003 Jul; 11(13):2723-8. PubMed ID: 12788346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and cytostatic and antiviral activities of 2'-deoxy-2',2'-difluororibo- and 2'-deoxy-2'-fluororibonucleosides derived from 7-(Het)aryl-7-deazaadenines.
    Perlíková P; Eberlin L; Ménová P; Raindlová V; Slavětínská L; Tloušťová E; Bahador G; Lee YJ; Hocek M
    ChemMedChem; 2013 May; 8(5):832-46. PubMed ID: 23559483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.