771 related articles for article (PubMed ID: 25173361)
1. Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.
Zhang YJ; Jansen-West K; Xu YF; Gendron TF; Bieniek KF; Lin WL; Sasaguri H; Caulfield T; Hubbard J; Daughrity L; Chew J; Belzil VV; Prudencio M; Stankowski JN; Castanedes-Casey M; Whitelaw E; Ash PE; DeTure M; Rademakers R; Boylan KB; Dickson DW; Petrucelli L
Acta Neuropathol; 2014 Oct; 128(4):505-24. PubMed ID: 25173361
[TBL] [Abstract][Full Text] [Related]
2. Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.
Gendron TF; Bieniek KF; Zhang YJ; Jansen-West K; Ash PE; Caulfield T; Daughrity L; Dunmore JH; Castanedes-Casey M; Chew J; Cosio DM; van Blitterswijk M; Lee WC; Rademakers R; Boylan KB; Dickson DW; Petrucelli L
Acta Neuropathol; 2013 Dec; 126(6):829-44. PubMed ID: 24129584
[TBL] [Abstract][Full Text] [Related]
3. Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.
Yamakawa M; Ito D; Honda T; Kubo K; Noda M; Nakajima K; Suzuki N
Hum Mol Genet; 2015 Mar; 24(6):1630-45. PubMed ID: 25398948
[TBL] [Abstract][Full Text] [Related]
4. Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS.
Ash PE; Bieniek KF; Gendron TF; Caulfield T; Lin WL; Dejesus-Hernandez M; van Blitterswijk MM; Jansen-West K; Paul JW; Rademakers R; Boylan KB; Dickson DW; Petrucelli L
Neuron; 2013 Feb; 77(4):639-46. PubMed ID: 23415312
[TBL] [Abstract][Full Text] [Related]
5. RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.
Zu T; Liu Y; Bañez-Coronel M; Reid T; Pletnikova O; Lewis J; Miller TM; Harms MB; Falchook AE; Subramony SH; Ostrow LW; Rothstein JD; Troncoso JC; Ranum LP
Proc Natl Acad Sci U S A; 2013 Dec; 110(51):E4968-77. PubMed ID: 24248382
[TBL] [Abstract][Full Text] [Related]
6. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
Chew J; Cook C; Gendron TF; Jansen-West K; Del Rosso G; Daughrity LM; Castanedes-Casey M; Kurti A; Stankowski JN; Disney MD; Rothstein JD; Dickson DW; Fryer JD; Zhang YJ; Petrucelli L
Mol Neurodegener; 2019 Feb; 14(1):9. PubMed ID: 30767771
[TBL] [Abstract][Full Text] [Related]
7. c9RAN translation: a potential therapeutic target for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia.
Gendron TF; Cosio DM; Petrucelli L
Expert Opin Ther Targets; 2013 Sep; 17(9):991-5. PubMed ID: 23844663
[TBL] [Abstract][Full Text] [Related]
8. Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers.
Gendron TF; van Blitterswijk M; Bieniek KF; Daughrity LM; Jiang J; Rush BK; Pedraza O; Lucas JA; Murray ME; Desaro P; Robertson A; Overstreet K; Thomas CS; Crook JE; Castanedes-Casey M; Rousseau L; Josephs KA; Parisi JE; Knopman DS; Petersen RC; Boeve BF; Graff-Radford NR; Rademakers R; Lagier-Tourenne C; Edbauer D; Cleveland DW; Dickson DW; Petrucelli L; Boylan KB
Acta Neuropathol; 2015 Oct; 130(4):559-73. PubMed ID: 26350237
[TBL] [Abstract][Full Text] [Related]
9. Clinical and neuropathologic heterogeneity of c9FTD/ALS associated with hexanucleotide repeat expansion in C9ORF72.
Murray ME; DeJesus-Hernandez M; Rutherford NJ; Baker M; Duara R; Graff-Radford NR; Wszolek ZK; Ferman TJ; Josephs KA; Boylan KB; Rademakers R; Dickson DW
Acta Neuropathol; 2011 Dec; 122(6):673-90. PubMed ID: 22083254
[TBL] [Abstract][Full Text] [Related]
10. Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
Su Z; Zhang Y; Gendron TF; Bauer PO; Chew J; Yang WY; Fostvedt E; Jansen-West K; Belzil VV; Desaro P; Johnston A; Overstreet K; Oh SY; Todd PK; Berry JD; Cudkowicz ME; Boeve BF; Dickson D; Floeter MK; Traynor BJ; Morelli C; Ratti A; Silani V; Rademakers R; Brown RH; Rothstein JD; Boylan KB; Petrucelli L; Disney MD
Neuron; 2014 Sep; 83(5):1043-50. PubMed ID: 25132468
[TBL] [Abstract][Full Text] [Related]
11. Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo.
Todd TW; McEachin ZT; Chew J; Burch AR; Jansen-West K; Tong J; Yue M; Song Y; Castanedes-Casey M; Kurti A; Dunmore JH; Fryer JD; Zhang YJ; San Millan B; Teijeira Bautista S; Arias M; Dickson D; Gendron TF; Sobrido MJ; Disney MD; Bassell GJ; Rossoll W; Petrucelli L
Cell Rep; 2020 May; 31(5):107616. PubMed ID: 32375043
[TBL] [Abstract][Full Text] [Related]
12. C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration.
May S; Hornburg D; Schludi MH; Arzberger T; Rentzsch K; Schwenk BM; Grässer FA; Mori K; Kremmer E; Banzhaf-Strathmann J; Mann M; Meissner F; Edbauer D
Acta Neuropathol; 2014 Oct; 128(4):485-503. PubMed ID: 25120191
[TBL] [Abstract][Full Text] [Related]
13. Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers.
Mackenzie IR; Frick P; Grässer FA; Gendron TF; Petrucelli L; Cashman NR; Edbauer D; Kremmer E; Prudlo J; Troost D; Neumann M
Acta Neuropathol; 2015 Dec; 130(6):845-61. PubMed ID: 26374446
[TBL] [Abstract][Full Text] [Related]
14. Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
Zhang YJ; Gendron TF; Ebbert MTW; O'Raw AD; Yue M; Jansen-West K; Zhang X; Prudencio M; Chew J; Cook CN; Daughrity LM; Tong J; Song Y; Pickles SR; Castanedes-Casey M; Kurti A; Rademakers R; Oskarsson B; Dickson DW; Hu W; Gitler AD; Fryer JD; Petrucelli L
Nat Med; 2018 Aug; 24(8):1136-1142. PubMed ID: 29942091
[TBL] [Abstract][Full Text] [Related]
15. Molecular Mechanisms of Neurodegeneration Related to
Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
[TBL] [Abstract][Full Text] [Related]
16. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
[TBL] [Abstract][Full Text] [Related]
17. Mechanisms of toxicity in C9FTLD/ALS.
Gendron TF; Belzil VV; Zhang YJ; Petrucelli L
Acta Neuropathol; 2014 Mar; 127(3):359-76. PubMed ID: 24394885
[TBL] [Abstract][Full Text] [Related]
18. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis.
Farg MA; Konopka A; Soo KY; Ito D; Atkin JD
Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984
[TBL] [Abstract][Full Text] [Related]
19. Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.
Nguyen L; Montrasio F; Pattamatta A; Tusi SK; Bardhi O; Meyer KD; Hayes L; Nakamura K; Banez-Coronel M; Coyne A; Guo S; Laboissonniere LA; Gu Y; Narayanan S; Smith B; Nitsch RM; Kankel MW; Rushe M; Rothstein J; Zu T; Grimm J; Ranum LPW
Neuron; 2020 Feb; 105(4):645-662.e11. PubMed ID: 31831332
[TBL] [Abstract][Full Text] [Related]
20. Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.
Wen X; Westergard T; Pasinelli P; Trotti D
Neurosci Lett; 2017 Jan; 636():16-26. PubMed ID: 27619540
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
