These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 25174872)

  • 41. BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents.
    Deng J; Carlson N; Takeyama K; Dal Cin P; Shipp M; Letai A
    Cancer Cell; 2007 Aug; 12(2):171-85. PubMed ID: 17692808
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Bone marrow microenvironment-derived signals induce Mcl-1 dependence in multiple myeloma.
    Gupta VA; Matulis SM; Conage-Pough JE; Nooka AK; Kaufman JL; Lonial S; Boise LH
    Blood; 2017 Apr; 129(14):1969-1979. PubMed ID: 28151428
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells.
    Aranovich A; Liu Q; Collins T; Geng F; Dixit S; Leber B; Andrews DW
    Mol Cell; 2012 Mar; 45(6):754-63. PubMed ID: 22464442
    [TBL] [Abstract][Full Text] [Related]  

  • 44. PUMA and BIM are required for oncogene inactivation-induced apoptosis.
    Bean GR; Ganesan YT; Dong Y; Takeda S; Liu H; Chan PM; Huang Y; Chodosh LA; Zambetti GP; Hsieh JJ; Cheng EH
    Sci Signal; 2013 Mar; 6(268):ra20. PubMed ID: 23532334
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics.
    Cragg MS; Kuroda J; Puthalakath H; Huang DC; Strasser A
    PLoS Med; 2007 Oct; 4(10):1681-89; discussion 1690. PubMed ID: 17973573
    [TBL] [Abstract][Full Text] [Related]  

  • 46. ABT-737 increases tyrosine kinase inhibitor-induced apoptosis in chronic myeloid leukemia cells through XIAP downregulation and sensitizes CD34(+) CD38(-) population to imatinib.
    Airiau K; Mahon FX; Josselin M; Jeanneteau M; Turcq B; Belloc F
    Exp Hematol; 2012 May; 40(5):367-78.e2. PubMed ID: 22240609
    [TBL] [Abstract][Full Text] [Related]  

  • 47. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
    J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Genetically defining the mechanism of Puma- and Bim-induced apoptosis.
    Garrison SP; Phillips DC; Jeffers JR; Chipuk JE; Parsons MJ; Rehg JE; Opferman JT; Green DR; Zambetti GP
    Cell Death Differ; 2012 Apr; 19(4):642-9. PubMed ID: 22015606
    [TBL] [Abstract][Full Text] [Related]  

  • 49. γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.
    Séveno C; Loussouarn D; Bréchet S; Campone M; Juin P; Barillé-Nion S
    Breast Cancer Res; 2012 Jun; 14(3):R96. PubMed ID: 22703841
    [TBL] [Abstract][Full Text] [Related]  

  • 50. The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
    Kodama T; Hikita H; Kawaguchi T; Saito Y; Tanaka S; Shigekawa M; Shimizu S; Li W; Miyagi T; Kanto T; Hiramatsu N; Tatsumi T; Takehara T
    J Biol Chem; 2013 Oct; 288(42):30009-30018. PubMed ID: 23986435
    [TBL] [Abstract][Full Text] [Related]  

  • 51. pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737.
    Bertin-Ciftci J; Barré B; Le Pen J; Maillet L; Couriaud C; Juin P; Braun F
    Cell Death Differ; 2013 May; 20(5):755-64. PubMed ID: 23429261
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Targeting the regulatory machinery of BIM for cancer therapy.
    Harada H; Grant S
    Crit Rev Eukaryot Gene Expr; 2012; 22(2):117-29. PubMed ID: 22856430
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Identification of predictive factors of response to the BH3-mimetic molecule ABT-737: an ex vivo experiment in human serous ovarian carcinoma.
    Lheureux S; N'Diaye M; Blanc-Fournier C; Dugué AE; Clarisse B; Dutoit S; Giffard F; Abeilard E; Briand M; Labiche A; Grellard JM; Crouet H; Martin S; Joly F; Poulain L
    Int J Cancer; 2015 Mar; 136(5):E340-50. PubMed ID: 25066666
    [TBL] [Abstract][Full Text] [Related]  

  • 54. BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia.
    Del Gaizo Moore V; Schlis KD; Sallan SE; Armstrong SA; Letai A
    Blood; 2008 Feb; 111(4):2300-9. PubMed ID: 18056841
    [TBL] [Abstract][Full Text] [Related]  

  • 55. IL-15 regulates Bcl-2 family members Bim and Mcl-1 through JAK/STAT and PI3K/AKT pathways in T cells.
    Shenoy AR; Kirschnek S; Häcker G
    Eur J Immunol; 2014 Aug; 44(8):2500-7. PubMed ID: 24825007
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.
    Yecies D; Carlson NE; Deng J; Letai A
    Blood; 2010 Apr; 115(16):3304-13. PubMed ID: 20197552
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.
    Coloff JL; Macintyre AN; Nichols AG; Liu T; Gallo CA; Plas DR; Rathmell JC
    Cancer Res; 2011 Aug; 71(15):5204-13. PubMed ID: 21670080
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.
    Rubert J; Qian Z; Andraos R; Guthy DA; Radimerski T
    BMC Cancer; 2011 Jan; 11():24. PubMed ID: 21247487
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Metastatic SW620 colon cancer cells are primed for death when detached and can be sensitized to anoikis by the BH3-mimetic ABT-737.
    Maamer-Azzabi A; Ndozangue-Touriguine O; Bréard J
    Cell Death Dis; 2013 Sep; 4(9):e801. PubMed ID: 24030153
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk.
    Ryder C; McColl K; Zhong F; Distelhorst CW
    J Biol Chem; 2012 Aug; 287(33):27863-75. PubMed ID: 22685289
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.