379 related articles for article (PubMed ID: 25175600)
1. Effect of individual Fc methionine oxidation on FcRn binding: Met252 oxidation impairs FcRn binding more profoundly than Met428 oxidation.
Gao X; Ji JA; Veeravalli K; Wang YJ; Zhang T; Mcgreevy W; Zheng K; Kelley RF; Laird MW; Liu J; Cromwell M
J Pharm Sci; 2015 Feb; 104(2):368-77. PubMed ID: 25175600
[TBL] [Abstract][Full Text] [Related]
2. A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies.
Stracke J; Emrich T; Rueger P; Schlothauer T; Kling L; Knaupp A; Hertenberger H; Wolfert A; Spick C; Lau W; Drabner G; Reiff U; Koll H; Papadimitriou A
MAbs; 2014; 6(5):1229-42. PubMed ID: 25517308
[TBL] [Abstract][Full Text] [Related]
3. Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies.
Wang W; Vlasak J; Li Y; Pristatsky P; Fang Y; Pittman T; Roman J; Wang Y; Prueksaritanont T; Ionescu R
Mol Immunol; 2011 Mar; 48(6-7):860-6. PubMed ID: 21256596
[TBL] [Abstract][Full Text] [Related]
4. Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.
Suzuki T; Ishii-Watabe A; Tada M; Kobayashi T; Kanayasu-Toyoda T; Kawanishi T; Yamaguchi T
J Immunol; 2010 Feb; 184(4):1968-76. PubMed ID: 20083659
[TBL] [Abstract][Full Text] [Related]
5. Methionine oxidation in human IgG2 Fc decreases binding affinities to protein A and FcRn.
Pan H; Chen K; Chu L; Kinderman F; Apostol I; Huang G
Protein Sci; 2009 Feb; 18(2):424-33. PubMed ID: 19165723
[TBL] [Abstract][Full Text] [Related]
6. The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.
Abdiche YN; Yeung YA; Chaparro-Riggers J; Barman I; Strop P; Chin SM; Pham A; Bolton G; McDonough D; Lindquist K; Pons J; Rajpal A
MAbs; 2015; 7(2):331-43. PubMed ID: 25658443
[TBL] [Abstract][Full Text] [Related]
7. Quantitative methods for developing Fc mutants with extended half-lives.
Kamei DT; Lao BJ; Ricci MS; Deshpande R; Xu H; Tidor B; Lauffenburger DA
Biotechnol Bioeng; 2005 Dec; 92(6):748-60. PubMed ID: 16136591
[TBL] [Abstract][Full Text] [Related]
8. Understanding the Impact of Methionine Oxidation on the Biological Functions of IgG1 Antibodies Using Hydrogen/Deuterium Exchange Mass Spectrometry.
Mo J; Yan Q; So CK; Soden T; Lewis MJ; Hu P
Anal Chem; 2016 Oct; 88(19):9495-9502. PubMed ID: 27575380
[TBL] [Abstract][Full Text] [Related]
9. Functional assessment of antibody oxidation by native mass spectrometry.
Haberger M; Heidenreich AK; Schlothauer T; Hook M; Gassner J; Bomans K; Yegres M; Zwick A; Zimmermann B; Wegele H; Bonnington L; Reusch D; Bulau P
MAbs; 2015; 7(5):891-900. PubMed ID: 26000623
[TBL] [Abstract][Full Text] [Related]
10. Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics.
Schoch A; Kettenberger H; Mundigl O; Winter G; Engert J; Heinrich J; Emrich T
Proc Natl Acad Sci U S A; 2015 May; 112(19):5997-6002. PubMed ID: 25918417
[TBL] [Abstract][Full Text] [Related]
11. Effect of protein aggregates on characterization of FcRn binding of Fc-fusion therapeutics.
Bajardi-Taccioli A; Blum A; Xu C; Sosic Z; Bergelson S; Feschenko M
Mol Immunol; 2015 Oct; 67(2 Pt B):616-24. PubMed ID: 26254986
[TBL] [Abstract][Full Text] [Related]
12. Characterization of the 2:1 complex between the class I MHC-related Fc receptor and its Fc ligand in solution.
Martin WL; Bjorkman PJ
Biochemistry; 1999 Sep; 38(39):12639-47. PubMed ID: 10504233
[TBL] [Abstract][Full Text] [Related]
13. Crystal structure of the complex of rat neonatal Fc receptor with Fc.
Burmeister WP; Huber AH; Bjorkman PJ
Nature; 1994 Nov; 372(6504):379-83. PubMed ID: 7969498
[TBL] [Abstract][Full Text] [Related]
14. Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics.
Mathur A; Arora T; Liu L; Crouse-Zeineddini J; Mukku V
J Immunol Methods; 2013 Apr; 390(1-2):81-91. PubMed ID: 23384837
[TBL] [Abstract][Full Text] [Related]
15. Characterization of the interactions of rabbit neonatal Fc receptor (FcRn) with rabbit and human IgG isotypes.
Szikora B; Hiripi L; Bender B; Kacskovics I; Iliás A
PLoS One; 2017; 12(9):e0185662. PubMed ID: 28957416
[TBL] [Abstract][Full Text] [Related]
16. Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
Burvenich IJG; Farrugia W; Liu Z; Makris D; King D; Gloria B; Perani A; Allan LC; Scott AM; Ramsland PA
Biochem J; 2018 Jul; 475(13):2179-2190. PubMed ID: 29794155
[TBL] [Abstract][Full Text] [Related]
17. Impact of methionine oxidation on the binding of human IgG1 to Fc Rn and Fc gamma receptors.
Bertolotti-Ciarlet A; Wang W; Lownes R; Pristatsky P; Fang Y; McKelvey T; Li Y; Li Y; Drummond J; Prueksaritanont T; Vlasak J
Mol Immunol; 2009 May; 46(8-9):1878-82. PubMed ID: 19269032
[TBL] [Abstract][Full Text] [Related]
18. Conformational Destabilization of Immunoglobulin G Increases the Low pH Binding Affinity with the Neonatal Fc Receptor.
Walters BT; Jensen PF; Larraillet V; Lin K; Patapoff T; Schlothauer T; Rand KD; Zhang J
J Biol Chem; 2016 Jan; 291(4):1817-1825. PubMed ID: 26627822
[TBL] [Abstract][Full Text] [Related]
19. The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin.
Andersen JT; Dee Qian J; Sandlie I
Eur J Immunol; 2006 Nov; 36(11):3044-51. PubMed ID: 17048273
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.
Martin WL; West AP; Gan L; Bjorkman PJ
Mol Cell; 2001 Apr; 7(4):867-77. PubMed ID: 11336709
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]