These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

379 related articles for article (PubMed ID: 25175600)

  • 101. Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates.
    Yeung YA; Leabman MK; Marvin JS; Qiu J; Adams CW; Lien S; Starovasnik MA; Lowman HB
    J Immunol; 2009 Jun; 182(12):7663-71. PubMed ID: 19494290
    [TBL] [Abstract][Full Text] [Related]  

  • 102. FcRn mediates elongated serum half-life of human IgG in cattle.
    Kacskovics I; Kis Z; Mayer B; West AP; Tiangco NE; Tilahun M; Cervenak L; Bjorkman PJ; Goldsby RA; Szenci O; Hammarström L
    Int Immunol; 2006 Apr; 18(4):525-36. PubMed ID: 16481343
    [TBL] [Abstract][Full Text] [Related]  

  • 103. Localization of the site of the IgG molecule that regulates maternofetal transmission in mice.
    Medesan C; Radu C; Kim JK; Ghetie V; Ward ES
    Eur J Immunol; 1996 Oct; 26(10):2533-6. PubMed ID: 8898970
    [TBL] [Abstract][Full Text] [Related]  

  • 104. FcRn: from molecular interactions to regulation of IgG pharmacokinetics and functions.
    Challa DK; Velmurugan R; Ober RJ; Sally Ward E
    Curr Top Microbiol Immunol; 2014; 382():249-72. PubMed ID: 25116104
    [TBL] [Abstract][Full Text] [Related]  

  • 105. The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies.
    Datta-Mannan A; Lu J; Witcher DR; Leung D; Tang Y; Wroblewski VJ
    MAbs; 2015; 7(6):1084-93. PubMed ID: 26337808
    [TBL] [Abstract][Full Text] [Related]  

  • 106. Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.
    Dall'Acqua WF; Woods RM; Ward ES; Palaszynski SR; Patel NK; Brewah YA; Wu H; Kiener PA; Langermann S
    J Immunol; 2002 Nov; 169(9):5171-80. PubMed ID: 12391234
    [TBL] [Abstract][Full Text] [Related]  

  • 107. Humanized IgG1 variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates.
    Datta-Mannan A; Witcher DR; Tang Y; Watkins J; Jiang W; Wroblewski VJ
    Drug Metab Dispos; 2007 Jan; 35(1):86-94. PubMed ID: 17050651
    [TBL] [Abstract][Full Text] [Related]  

  • 108. Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies.
    Ober RJ; Radu CG; Ghetie V; Ward ES
    Int Immunol; 2001 Dec; 13(12):1551-9. PubMed ID: 11717196
    [TBL] [Abstract][Full Text] [Related]  

  • 109. Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding.
    Andersen JT; Daba MB; Berntzen G; Michaelsen TE; Sandlie I
    J Biol Chem; 2010 Feb; 285(7):4826-36. PubMed ID: 20018855
    [TBL] [Abstract][Full Text] [Related]  

  • 110. The influence of antibody engineering on Fc conformation and Fc receptor binding properties: Analysis of FcRn-binding engineered antibodies and an Fc fusion protein.
    Suzuki T; Hashii N; Tada M; Ishii-Watabe A
    MAbs; 2021; 13(1):1923366. PubMed ID: 34030575
    [TBL] [Abstract][Full Text] [Related]  

  • 111. Monovalent IgG4 molecules: immunoglobulin Fc mutations that result in a monomeric structure.
    Wilkinson IC; Fowler SB; Machiesky L; Miller K; Hayes DB; Adib M; Her C; Borrok MJ; Tsui P; Burrell M; Corkill DJ; Witt S; Lowe DC; Webster CI
    MAbs; 2013; 5(3):406-17. PubMed ID: 23567207
    [TBL] [Abstract][Full Text] [Related]  

  • 112. Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathway.
    Dickinson BL; Claypool SM; D'Angelo JA; Aiken ML; Venu N; Yen EH; Wagner JS; Borawski JA; Pierce AT; Hershberg R; Blumberg RS; Lencer WI
    Mol Biol Cell; 2008 Jan; 19(1):414-23. PubMed ID: 18003977
    [TBL] [Abstract][Full Text] [Related]  

  • 113. pH-dependent binding engineering reveals an FcRn affinity threshold that governs IgG recycling.
    Borrok MJ; Wu Y; Beyaz N; Yu XQ; Oganesyan V; Dall'Acqua WF; Tsui P
    J Biol Chem; 2015 Feb; 290(7):4282-90. PubMed ID: 25538249
    [TBL] [Abstract][Full Text] [Related]  

  • 114. Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.
    Andersen JT; Dalhus B; Cameron J; Daba MB; Plumridge A; Evans L; Brennan SO; Gunnarsen KS; Bjørås M; Sleep D; Sandlie I
    Nat Commun; 2012 Jan; 3():610. PubMed ID: 22215085
    [TBL] [Abstract][Full Text] [Related]  

  • 115. Site-Specific Hydrolysis Reaction C-Terminal of Methionine in Met-His during Metal-Catalyzed Oxidation of IgG-1.
    Mozziconacci O; Arora J; Toth RT; Joshi SB; Zhou S; Volkin DB; Schöneich C
    Mol Pharm; 2016 Apr; 13(4):1317-28. PubMed ID: 26942274
    [TBL] [Abstract][Full Text] [Related]  

  • 116. Mechanism-Based Competitive Binding Model to Investigate the Effect of Neonatal Fc Receptor Binding Affinity on the Pharmacokinetic of Humanized Anti-VEGF Monoclonal IgG1 Antibody in Cynomolgus Monkey.
    Ng CM; Fielder PJ; Jin J; Deng R
    AAPS J; 2016 Jul; 18(4):948-59. PubMed ID: 27075465
    [TBL] [Abstract][Full Text] [Related]  

  • 117. Selection of IgG Variants with Increased FcRn Binding Using Random and Directed Mutagenesis: Impact on Effector Functions.
    Monnet C; Jorieux S; Urbain R; Fournier N; Bouayadi K; De Romeuf C; Behrens CK; Fontayne A; Mondon P
    Front Immunol; 2015; 6():39. PubMed ID: 25699055
    [TBL] [Abstract][Full Text] [Related]  

  • 118. Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance.
    Goulet DR; Watson MJ; Tam SH; Zwolak A; Chiu ML; Atkins WM; Nath A
    Drug Metab Dispos; 2018 Dec; 46(12):1900-1907. PubMed ID: 30232177
    [TBL] [Abstract][Full Text] [Related]  

  • 119. Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies.
    Vaccaro C; Bawdon R; Wanjie S; Ober RJ; Ward ES
    Proc Natl Acad Sci U S A; 2006 Dec; 103(49):18709-14. PubMed ID: 17116867
    [TBL] [Abstract][Full Text] [Related]  

  • 120. Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc receptor (FcRn).
    Sand KM; Bern M; Nilsen J; Dalhus B; Gunnarsen KS; Cameron J; Grevys A; Bunting K; Sandlie I; Andersen JT
    J Biol Chem; 2014 Dec; 289(50):34583-94. PubMed ID: 25344603
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.