These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

283 related articles for article (PubMed ID: 25176651)

  • 1. Luminal cells are favored as the cell of origin for prostate cancer.
    Wang ZA; Toivanen R; Bergren SK; Chambon P; Shen MM
    Cell Rep; 2014 Sep; 8(5):1339-46. PubMed ID: 25176651
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A luminal epithelial stem cell that is a cell of origin for prostate cancer.
    Wang X; Kruithof-de Julio M; Economides KD; Walker D; Yu H; Halili MV; Hu YP; Price SM; Abate-Shen C; Shen MM
    Nature; 2009 Sep; 461(7263):495-500. PubMed ID: 19741607
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells.
    Iwata T; Schultz D; Hicks J; Hubbard GK; Mutton LN; Lotan TL; Bethel C; Lotz MT; Yegnasubramanian S; Nelson WG; Dang CV; Xu M; Anele U; Koh CM; Bieberich CJ; De Marzo AM
    PLoS One; 2010 Feb; 5(2):e9427. PubMed ID: 20195545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay.
    Park JW; Lee JK; Phillips JW; Huang P; Cheng D; Huang J; Witte ON
    Proc Natl Acad Sci U S A; 2016 Apr; 113(16):4482-7. PubMed ID: 27044116
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis.
    Song H; Zhang B; Watson MA; Humphrey PA; Lim H; Milbrandt J
    Oncogene; 2009 Sep; 28(37):3307-19. PubMed ID: 19597465
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.
    Berger PL; Frank SB; Schulz VV; Nollet EA; Edick MJ; Holly B; Chang TT; Hostetter G; Kim S; Miranti CK
    Cancer Res; 2014 Jun; 74(12):3357-68. PubMed ID: 24762396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential requirements for β-catenin in murine prostate cancer originating from basal versus luminal cells.
    Lu TL; Chen CM
    J Pathol; 2015 Jul; 236(3):290-301. PubMed ID: 25712462
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conditionally ablated Pten in prostate basal cells promotes basal-to-luminal differentiation and causes invasive prostate cancer in mice.
    Lu TL; Huang YF; You LR; Chao NC; Su FY; Chang JL; Chen CM
    Am J Pathol; 2013 Mar; 182(3):975-91. PubMed ID: 23313138
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer.
    Hubbard GK; Mutton LN; Khalili M; McMullin RP; Hicks JL; Bianchi-Frias D; Horn LA; Kulac I; Moubarek MS; Nelson PS; Yegnasubramanian S; De Marzo AM; Bieberich CJ
    Cancer Res; 2016 Jan; 76(2):283-92. PubMed ID: 26554830
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TGFβ signaling limits lineage plasticity in prostate cancer.
    Hao Y; Bjerke GA; Pietrzak K; Melhuish TA; Han Y; Turner SD; Frierson HF; Wotton D
    PLoS Genet; 2018 May; 14(5):e1007409. PubMed ID: 29782499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity.
    Wang ZA; Mitrofanova A; Bergren SK; Abate-Shen C; Cardiff RD; Califano A; Shen MM
    Nat Cell Biol; 2013 Mar; 15(3):274-83. PubMed ID: 23434823
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
    Anderson PD; McKissic SA; Logan M; Roh M; Franco OE; Wang J; Doubinskaia I; van der Meer R; Hayward SW; Eischen CM; Eltoum IE; Abdulkadir SA
    J Clin Invest; 2012 May; 122(5):1907-19. PubMed ID: 22484818
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN.
    Sharma P; Knowell AE; Chinaranagari S; Komaragiri S; Nagappan P; Patel D; Havrda MC; Chaudhary J
    Mol Cancer; 2013 Jun; 12():67. PubMed ID: 23786676
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips.
    Guo W; Li L; He J; Liu Z; Han M; Li F; Xia X; Zhang X; Zhu Y; Wei Y; Li Y; Aji R; Dai H; Wei H; Li C; Chen Y; Chen L; Gao D
    Nat Genet; 2020 Sep; 52(9):908-918. PubMed ID: 32807988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
    Bowen C; Ostrowski MC; Leone G; Gelmann EP
    Cancer Res; 2019 Aug; 79(16):4124-4134. PubMed ID: 31213464
    [No Abstract]   [Full Text] [Related]  

  • 16. Prostate stem cells and prostate cancer.
    Lawson DA; Xin L; Lukacs R; Xu Q; Cheng D; Witte ON
    Cold Spring Harb Symp Quant Biol; 2005; 70():187-96. PubMed ID: 16869753
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Accumulating progenitor cells in the luminal epithelial cell layer are candidate tumor initiating cells in a Pten knockout mouse prostate cancer model.
    Korsten H; Ziel-van der Made A; Ma X; van der Kwast T; Trapman J
    PLoS One; 2009 May; 4(5):e5662. PubMed ID: 19461893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.
    Kim J; Eltoum IE; Roh M; Wang J; Abdulkadir SA
    PLoS Genet; 2009 Jul; 5(7):e1000542. PubMed ID: 19578399
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin.
    Kwon OJ; Zhang L; Ittmann MM; Xin L
    Proc Natl Acad Sci U S A; 2014 Feb; 111(5):E592-600. PubMed ID: 24367088
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation.
    Choi N; Zhang B; Zhang L; Ittmann M; Xin L
    Cancer Cell; 2012 Feb; 21(2):253-65. PubMed ID: 22340597
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.