203 related articles for article (PubMed ID: 25178484)
1. RASopathy-associated CBL germline mutations cause aberrant ubiquitylation and trafficking of EGFR.
Brand K; Kentsch H; Glashoff C; Rosenberger G
Hum Mutat; 2014 Nov; 35(11):1372-81. PubMed ID: 25178484
[TBL] [Abstract][Full Text] [Related]
2. Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype.
Martinelli S; De Luca A; Stellacci E; Rossi C; Checquolo S; Lepri F; Caputo V; Silvano M; Buscherini F; Consoli F; Ferrara G; Digilio MC; Cavaliere ML; van Hagen JM; Zampino G; van der Burgt I; Ferrero GB; Mazzanti L; Screpanti I; Yntema HG; Nillesen WM; Savarirayan R; Zenker M; Dallapiccola B; Gelb BD; Tartaglia M
Am J Hum Genet; 2010 Aug; 87(2):250-7. PubMed ID: 20619386
[TBL] [Abstract][Full Text] [Related]
3. Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor.
Oksvold MP; Thien CB; Widerberg J; Chantry A; Huitfeldt HS; Langdon WY
Oncogene; 2003 Nov; 22(52):8509-18. PubMed ID: 14627991
[TBL] [Abstract][Full Text] [Related]
4. Germline mutation of CBL is associated with moyamoya disease in a child with juvenile myelomonocytic leukemia and Noonan syndrome-like disorder.
Hyakuna N; Muramatsu H; Higa T; Chinen Y; Wang X; Kojima S
Pediatr Blood Cancer; 2015 Mar; 62(3):542-4. PubMed ID: 25283271
[TBL] [Abstract][Full Text] [Related]
5. Molecular Diversity and Associated Phenotypic Spectrum of Germline CBL Mutations.
Martinelli S; Stellacci E; Pannone L; D'Agostino D; Consoli F; Lissewski C; Silvano M; Cencelli G; Lepri F; Maitz S; Pauli S; Rauch A; Zampino G; Selicorni A; Melançon S; Digilio MC; Gelb BD; De Luca A; Dallapiccola B; Zenker M; Tartaglia M
Hum Mutat; 2015 Aug; 36(8):787-96. PubMed ID: 25952305
[TBL] [Abstract][Full Text] [Related]
6. Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth.
Wisniewski DJ; Liyasova MS; Korrapati S; Zhang X; Ratnayake S; Chen Q; Gilbert SF; Catalano A; Voeller D; Meerzaman D; Guha U; Porat-Shliom N; Annunziata CM; Lipkowitz S
J Biol Chem; 2023 Jan; 299(1):102766. PubMed ID: 36470425
[TBL] [Abstract][Full Text] [Related]
7. Knockout of c-Cbl slows EGFR endocytic trafficking and enhances EGFR signaling despite incompletely blocking receptor ubiquitylation.
Crotchett BLM; Ceresa BP
Pharmacol Res Perspect; 2021 Apr; 9(2):e00756. PubMed ID: 33811466
[TBL] [Abstract][Full Text] [Related]
8. A case of splenomegaly in CBL syndrome.
Coe RR; McKinnon ML; Tarailo-Graovac M; Ross CJ; Wasserman WW; Friedman JM; Rogers PC; van Karnebeek CDM
Eur J Med Genet; 2017 Jul; 60(7):374-379. PubMed ID: 28414188
[TBL] [Abstract][Full Text] [Related]
9. A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling.
Waterman H; Katz M; Rubin C; Shtiegman K; Lavi S; Elson A; Jovin T; Yarden Y
EMBO J; 2002 Feb; 21(3):303-13. PubMed ID: 11823423
[TBL] [Abstract][Full Text] [Related]
10. Cbl and Itch binding sites in ERBB4 CYT-1 and CYT-2 mediate K48- and K63-polyubiquitination, respectively.
Meijer IM; van Rotterdam W; van Zoelen EJ; van Leeuwen JE
Cell Signal; 2013 Feb; 25(2):470-8. PubMed ID: 23153581
[TBL] [Abstract][Full Text] [Related]
11. The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor.
Smith CJ; Berry DM; McGlade CJ
J Cell Sci; 2013 Mar; 126(Pt 6):1366-80. PubMed ID: 23418353
[TBL] [Abstract][Full Text] [Related]
12. Noonan, Costello and cardio-facio-cutaneous syndromes: dysregulation of the Ras-MAPK pathway.
Tidyman WE; Rauen KA
Expert Rev Mol Med; 2008 Dec; 10():e37. PubMed ID: 19063751
[TBL] [Abstract][Full Text] [Related]
13. αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor.
Kortüm F; Harms FL; Hennighausen N; Rosenberger G
PLoS One; 2015; 10(7):e0132737. PubMed ID: 26177020
[TBL] [Abstract][Full Text] [Related]
14. Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF.
Oksvold MP; Skarpen E; Wierød L; Paulsen RE; Huitfeldt HS
Eur J Cell Biol; 2001 Apr; 80(4):285-94. PubMed ID: 11370743
[TBL] [Abstract][Full Text] [Related]
15. Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling.
Motta M; Fidan M; Bellacchio E; Pantaleoni F; Schneider-Heieck K; Coppola S; Borck G; Salviati L; Zenker M; Cirstea IC; Tartaglia M
Hum Mol Genet; 2019 Mar; 28(6):1007-1022. PubMed ID: 30481304
[TBL] [Abstract][Full Text] [Related]
16. The Cbl RING finger C-terminal flank controls epidermal growth factor receptor fate downstream of receptor ubiquitination.
Visser GD; Lill NL
Exp Cell Res; 2005 Dec; 311(2):281-93. PubMed ID: 16246327
[TBL] [Abstract][Full Text] [Related]
17. The ShcD phosphotyrosine adaptor subverts canonical EGF receptor trafficking.
Wills MKB; Lau HR; Jones N
J Cell Sci; 2017 Sep; 130(17):2808-2820. PubMed ID: 28724758
[TBL] [Abstract][Full Text] [Related]
18. Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor.
Odintsova E; van Niel G; Conjeaud H; Raposo G; Iwamoto R; Mekada E; Berditchevski F
J Biol Chem; 2013 Sep; 288(36):26323-26334. PubMed ID: 23897813
[TBL] [Abstract][Full Text] [Related]
19. Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation.
Grøvdal LM; Stang E; Sorkin A; Madshus IH
Exp Cell Res; 2004 Nov; 300(2):388-95. PubMed ID: 15475003
[TBL] [Abstract][Full Text] [Related]
20. Essential role of c-Cbl in amphiregulin-induced recycling and signaling of the endogenous epidermal growth factor receptor.
Baldys A; Göoz M; Morinelli TA; Lee MH; Raymond JR; Luttrell LM; Raymond JR
Biochemistry; 2009 Feb; 48(7):1462-73. PubMed ID: 19173594
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
