BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 25182962)

  • 1. Pyrazolone-quinazolone hybrids: a novel class of human 4-hydroxyphenylpyruvate dioxygenase inhibitors.
    Xu YL; Lin HY; Cao RJ; Ming ZZ; Yang WC; Yang GF
    Bioorg Med Chem; 2014 Oct; 22(19):5194-211. PubMed ID: 25182962
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and bioevaluation of pyrazole-benzimidazolone hybrids as novel human 4-Hydroxyphenylpyruvate dioxygenase inhibitors.
    Xu YL; Lin HY; Ruan X; Yang SG; Hao GF; Yang WC; Yang GF
    Eur J Med Chem; 2015 Mar; 92():427-38. PubMed ID: 25590863
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydrophobicity-oriented drug design (HODD) of new human 4-hydroxyphenylpyruvate dioxygenase inhibitors.
    Ndikuryayo F; Kang WM; Wu FX; Yang WC; Yang GF
    Eur J Med Chem; 2019 Mar; 166():22-31. PubMed ID: 30684868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of (4-hydroxyphenyl)pyruvate dioxygenase with the specific inhibitor 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione.
    Kavana M; Moran GR
    Biochemistry; 2003 Sep; 42(34):10238-45. PubMed ID: 12939152
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of Novel Pyrazole-Quinazoline-2,4-dione Hybrids as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
    He B; Wu FX; Yu LK; Wu L; Chen Q; Hao GF; Yang WC; Lin HY; Yang GF
    J Agric Food Chem; 2020 May; 68(18):5059-5067. PubMed ID: 32286826
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of 4-hydroxyphenylpyruvate dioxygenase by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione and 2-(2-chloro-4-methanesulfonylbenzoyl)-cyclohexane-1,3-dione.
    Ellis MK; Whitfield AC; Gowans LA; Auton TR; Provan WM; Lock EA; Smith LL
    Toxicol Appl Pharmacol; 1995 Jul; 133(1):12-9. PubMed ID: 7597701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-Hydroxyphenylpyruvate dioxygenase.
    Moran GR
    Arch Biochem Biophys; 2005 Jan; 433(1):117-28. PubMed ID: 15581571
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New Research for Quinazoline-2,4-diones as HPPD Inhibitors Based on 2D-MLR and 3D-QSAR Models.
    Fu Y; Sun YN; Cao HF; Yi KH; Zhao LX; Li JZ; Ye F
    Comb Chem High Throughput Screen; 2017; 20(9):748-759. PubMed ID: 28637410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined 3D-quantitative structure-activity relationships and topomer technology-based molecular design of human 4-hydroxyphenylpyruvate dioxygenase inhibitors.
    Liu YX; Gao S; Ye T; Li JZ; Ye F; Fu Y
    Future Med Chem; 2020 May; 12(9):795-811. PubMed ID: 32223563
    [No Abstract]   [Full Text] [Related]  

  • 10. Inhibition of para-Hydroxyphenylpyruvate Dioxygenase by Analogues of the Herbicide Nitisinone As a Strategy to Decrease Homogentisic Acid Levels, the Causative Agent of Alkaptonuria.
    Laschi M; Bernardini G; Dreassi E; Millucci L; Geminiani M; Braconi D; Marzocchi B; Botta M; Manetti F; Santucci A
    ChemMedChem; 2016 Apr; 11(7):674-8. PubMed ID: 26947423
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: active site contributions to drug inhibition.
    Neidig ML; Decker A; Kavana M; Moran GR; Solomon EI
    Biochem Biophys Res Commun; 2005 Dec; 338(1):206-14. PubMed ID: 16197918
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and herbicidal activity of novel quinazoline-2,4-diones as 4-hydroxyphenylpyruvate dioxygenase inhibitors.
    Wang DW; Lin HY; Cao RJ; Ming ZZ; Chen T; Hao GF; Yang WC; Yang GF
    Pest Manag Sci; 2015 Aug; 71(8):1122-32. PubMed ID: 25185782
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases.
    Santucci A; Bernardini G; Braconi D; Petricci E; Manetti F
    J Med Chem; 2017 May; 60(10):4101-4125. PubMed ID: 28128559
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pyrazole-Isoindoline-1,3-dione Hybrid: A Promising Scaffold for 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
    He B; Dong J; Lin HY; Wang MY; Li XK; Zheng BF; Chen Q; Hao GF; Yang WC; Yang GF
    J Agric Food Chem; 2019 Oct; 67(39):10844-10852. PubMed ID: 31525997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the ferrous form of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis in complex with the therapeutic herbicide, NTBC.
    Brownlee JM; Johnson-Winters K; Harrison DH; Moran GR
    Biochemistry; 2004 Jun; 43(21):6370-7. PubMed ID: 15157070
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Herbicidal 4-hydroxyphenylpyruvate dioxygenase inhibitors--a review of the triketone chemistry story from a Syngenta perspective.
    Beaudegnies R; Edmunds AJ; Fraser TE; Hall RG; Hawkes TR; Mitchell G; Schaetzer J; Wendeborn S; Wibley J
    Bioorg Med Chem; 2009 Jun; 17(12):4134-52. PubMed ID: 19349184
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and herbicidal evaluation of triketone-containing quinazoline-2,4-diones.
    Wang DW; Lin HY; Cao RJ; Yang SG; Chen Q; Hao GF; Yang WC; Yang GF
    J Agric Food Chem; 2014 Dec; 62(49):11786-96. PubMed ID: 25405813
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Herbicidal Activity of Triketone-Quinoline Hybrids as Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
    Wang DW; Lin HY; Cao RJ; Chen T; Wu FX; Hao GF; Chen Q; Yang WC; Yang GF
    J Agric Food Chem; 2015 Jun; 63(23):5587-96. PubMed ID: 26006257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of
    Fu Y; Zhang D; Zhang SQ; Liu YX; Guo YY; Wang MX; Gao S; Zhao LX; Ye F
    J Agric Food Chem; 2019 Oct; 67(43):11839-11847. PubMed ID: 31589436
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Isolation of herbicide-resistant 4-hydroxyphenylpyruvate dioxygenase from cultured Coptis japonica cells.
    Liang Y; Minami H; Sato F
    Biosci Biotechnol Biochem; 2008 Nov; 72(11):3059-62. PubMed ID: 18997404
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.