BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 25188840)

  • 1. In vitro analysis of carboxyacyl substrate tolerance in the loading and first extension modules of borrelidin polyketide synthase.
    Hagen A; Poust S; de Rond T; Yuzawa S; Katz L; Adams PD; Petzold CJ; Keasling JD
    Biochemistry; 2014 Sep; 53(38):5975-7. PubMed ID: 25188840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksA.
    Huitt-Roehl CR; Hill EA; Adams MM; Vagstad AL; Li JW; Townsend CA
    ACS Chem Biol; 2015 Jun; 10(6):1443-9. PubMed ID: 25714897
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate controlled divergence in polyketide synthase catalysis.
    Hansen DA; Koch AA; Sherman DH
    J Am Chem Soc; 2015 Mar; 137(11):3735-8. PubMed ID: 25730816
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Iterative polyketide biosynthesis by modular polyketide synthases in bacteria.
    Chen H; Du L
    Appl Microbiol Biotechnol; 2016 Jan; 100(2):541-57. PubMed ID: 26549236
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expanding Extender Substrate Selection for Unnatural Polyketide Biosynthesis by Acyltransferase Domain Exchange within a Modular Polyketide Synthase.
    Englund E; Schmidt M; Nava AA; Lechner A; Deng K; Jocic R; Lin Y; Roberts J; Benites VT; Kakumanu R; Gin JW; Chen Y; Liu Y; Petzold CJ; Baidoo EEK; Northen TR; Adams PD; Katz L; Yuzawa S; Keasling JD
    J Am Chem Soc; 2023 Apr; 145(16):8822-8832. PubMed ID: 37057992
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fungal type III polyketide synthases.
    Hashimoto M; Nonaka T; Fujii I
    Nat Prod Rep; 2014 Oct; 31(10):1306-17. PubMed ID: 25182423
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineering a Polyketide Synthase for In Vitro Production of Adipic Acid.
    Hagen A; Poust S; Rond Td; Fortman JL; Katz L; Petzold CJ; Keasling JD
    ACS Synth Biol; 2016 Jan; 5(1):21-7. PubMed ID: 26501439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases.
    Barajas JF; McAndrew RP; Thompson MG; Backman TWH; Pang B; de Rond T; Pereira JH; Benites VT; Martín HG; Baidoo EEK; Hillson NJ; Adams PD; Keasling JD
    J Ind Microbiol Biotechnol; 2019 Aug; 46(8):1225-1235. PubMed ID: 31115703
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights into polyketide biosynthesis gained from repurposing antibiotic-producing polyketide synthases to produce fuels and chemicals.
    Yuzawa S; Keasling JD; Katz L
    J Antibiot (Tokyo); 2016 Jul; 69(7):494-9. PubMed ID: 27245558
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering.
    Koryakina I; Kasey C; McArthur JB; Lowell AN; Chemler JA; Li S; Hansen DA; Sherman DH; Williams GJ
    ACS Chem Biol; 2017 Jan; 12(1):114-123. PubMed ID: 28103677
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum.
    Wilkinson CJ; Frost EJ; Staunton J; Leadlay PF
    Chem Biol; 2001 Dec; 8(12):1197-208. PubMed ID: 11755398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Structural Enzymology of Iterative Aromatic Polyketide Synthases: A Critical Comparison with Fatty Acid Synthases.
    Tsai SC
    Annu Rev Biochem; 2018 Jun; 87():503-531. PubMed ID: 29925265
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural and functional analysis of the loading acyltransferase from avermectin modular polyketide synthase.
    Wang F; Wang Y; Ji J; Zhou Z; Yu J; Zhu H; Su Z; Zhang L; Zheng J
    ACS Chem Biol; 2015 Apr; 10(4):1017-25. PubMed ID: 25581064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides.
    Poust S; Phelan RM; Deng K; Katz L; Petzold CJ; Keasling JD
    Angew Chem Int Ed Engl; 2015 Feb; 54(8):2370-3. PubMed ID: 25564997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An Oxetane-Based Polyketide Surrogate To Probe Substrate Binding in a Polyketide Synthase.
    Ellis BD; Milligan JC; White AR; Duong V; Altman PX; Mohammed LY; Crump MP; Crosby J; Luo R; Vanderwal CD; Tsai SC
    J Am Chem Soc; 2018 Apr; 140(15):4961-4964. PubMed ID: 29620883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biosynthesis of polyketides by
    Chen H; Bian Z; Ravichandran V; Li R; Sun Y; Huo L; Fu J; Bian X; Xia L; Tu Q; Zhang Y
    Crit Rev Microbiol; 2019 Mar; 45(2):162-181. PubMed ID: 31218924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evolution of metabolic diversity: insights from microbial polyketide synthases.
    Jenke-Kodama H; Dittmann E
    Phytochemistry; 2009; 70(15-16):1858-66. PubMed ID: 19619887
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The DEBS paradigm for type I modular polyketide synthases and beyond.
    Katz L
    Methods Enzymol; 2009; 459():113-42. PubMed ID: 19362638
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing the Flexibility of an Iterative Modular Polyketide Synthase with Non-Native Substrates in Vitro.
    Curran SC; Hagen A; Poust S; Chan LJG; Garabedian BM; de Rond T; Baluyot MJ; Vu JT; Lau AK; Yuzawa S; Petzold CJ; Katz L; Keasling JD
    ACS Chem Biol; 2018 Aug; 13(8):2261-2268. PubMed ID: 29912551
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multimodular type I polyketide synthases in algae evolve by module duplications and displacement of AT domains in trans.
    Shelest E; Heimerl N; Fichtner M; Sasso S
    BMC Genomics; 2015 Nov; 16():1015. PubMed ID: 26611533
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.