These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 25192260)

  • 41. Discovery of potent inhibitors of receptor protein tyrosine phosphatase sigma through the structure-based virtual screening.
    Park H; Chien PN; Ryu SE
    Bioorg Med Chem Lett; 2012 Oct; 22(20):6333-7. PubMed ID: 22989533
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Combining horizontal and vertical substructure relationships in scaffold hierarchies for activity prediction.
    Hu Y; Bajorath J
    J Chem Inf Model; 2011 Feb; 51(2):248-57. PubMed ID: 21271729
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Identification of small molecule sphingomyelin synthase inhibitors.
    Deng X; Lin F; Zhang Y; Li Y; Zhou L; Lou B; Li Y; Dong J; Ding T; Jiang X; Wang R; Ye D
    Eur J Med Chem; 2014 Feb; 73():1-7. PubMed ID: 24374347
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Discovery of novel inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening.
    Zhang M; Zhu W; Li Y
    Eur J Med Chem; 2013 Apr; 62():301-10. PubMed ID: 23376248
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
    Dalgarno D; Stehle T; Narula S; Schelling P; van Schravendijk MR; Adams S; Andrade L; Keats J; Ram M; Jin L; Grossman T; MacNeil I; Metcalf C; Shakespeare W; Wang Y; Keenan T; Sundaramoorthi R; Bohacek R; Weigele M; Sawyer T
    Chem Biol Drug Des; 2006 Jan; 67(1):46-57. PubMed ID: 16492148
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Identification and characterization of new inhibitors of fungal homoserine kinase.
    De Pascale G; Griffiths EJ; Shakya T; Nazi I; Wright GD
    Chembiochem; 2011 May; 12(8):1179-82. PubMed ID: 21538764
    [No Abstract]   [Full Text] [Related]  

  • 47. Comparison of 2D fingerprint methods for multiple-template similarity searching on compound activity classes of increasing structural diversity.
    Tovar A; Eckert H; Bajorath J
    ChemMedChem; 2007 Feb; 2(2):208-17. PubMed ID: 17143917
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Discovery of the first inhibitors of bacterial enzyme D-aspartate ligase from Enterococcus faecium (Aslfm).
    Škedelj V; Perdih A; Brvar M; Kroflič A; Dubbée V; Savage V; O'Neill AJ; Solmajer T; Bešter-Rogač M; Blanot D; Hugonnet JE; Magnet S; Arthur M; Mainardi JL; Stojan J; Zega A
    Eur J Med Chem; 2013 Sep; 67():208-20. PubMed ID: 23867605
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Kinase patent space visualization using chemical replacements.
    Southall NT; Ajay
    J Med Chem; 2006 Mar; 49(6):2103-9. PubMed ID: 16539399
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Identification of bromophenol thiohydantoin as an inhibitor of DisA, a c-di-AMP synthase, from a 1000 compound library, using the coralyne assay.
    Zheng Y; Zhou J; Sayre DA; Sintim HO
    Chem Commun (Camb); 2014 Oct; 50(76):11234-7. PubMed ID: 25116237
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Neighborhood-based prediction of novel active compounds from SAR matrices.
    Gupta-Ostermann D; Shanmugasundaram V; Bajorath J
    J Chem Inf Model; 2014 Mar; 54(3):801-9. PubMed ID: 24593807
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Structurally diversified heterocycles and related privileged scaffolds as potential urease inhibitors: a brief overview.
    Ibrar A; Khan I; Abbas N
    Arch Pharm (Weinheim); 2013 Jun; 346(6):423-46. PubMed ID: 23712847
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Structure-based design and optimization of potent renin inhibitors on 5- or 7-azaindole-scaffolds.
    Matter H; Scheiper B; Steinhagen H; Böcskei Z; Fleury V; McCort G
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5487-92. PubMed ID: 21840215
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Polypharmacology directed compound data mining: identification of promiscuous chemotypes with different activity profiles and comparison to approved drugs.
    Hu Y; Bajorath J
    J Chem Inf Model; 2010 Dec; 50(12):2112-8. PubMed ID: 21070069
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Efficient search of chemical space: navigating from fragments to structurally diverse chemotypes.
    Wassermann AM; Kutchukian PS; Lounkine E; Luethi T; Hamon J; Bocker MT; Malik HA; Cowan-Jacob SW; Glick M
    J Med Chem; 2013 Nov; 56(21):8879-91. PubMed ID: 24117015
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Expanding the medicinally relevant chemical space with compound libraries.
    López-Vallejo F; Giulianotti MA; Houghten RA; Medina-Franco JL
    Drug Discov Today; 2012 Jul; 17(13-14):718-26. PubMed ID: 22515962
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Discovery and pharmacological characterization of a novel small molecule inhibitor of phosphatidylinositol-5-phosphate 4-kinase, type II, beta.
    Voss MD; Czechtizky W; Li Z; Rudolph C; Petry S; Brummerhop H; Langer T; Schiffer A; Schaefer HL
    Biochem Biophys Res Commun; 2014 Jul; 449(3):327-31. PubMed ID: 24845568
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Scaffold oriented synthesis. Part 1: Design, preparation, and biological evaluation of thienopyrazoles as kinase inhibitors.
    Akritopoulou-Zanze I; Darczak D; Sarris K; Phelan KM; Huth JR; Song D; Johnson EF; Jia Y; Djuric SW
    Bioorg Med Chem Lett; 2006 Jan; 16(1):96-9. PubMed ID: 16216502
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Synthesis and target identification of hymenialdisine analogs.
    Wan Y; Hur W; Cho CY; Liu Y; Adrian FJ; Lozach O; Bach S; Mayer T; Fabbro D; Meijer L; Gray NS
    Chem Biol; 2004 Feb; 11(2):247-59. PubMed ID: 15123286
    [TBL] [Abstract][Full Text] [Related]  

  • 60. SAR Matrix Method for Large-Scale Analysis of Compound Structure-Activity Relationships and Exploration of Multitarget Activity Spaces.
    Hu Y; Bajorath J
    Methods Mol Biol; 2018; 1825():339-352. PubMed ID: 30334212
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.