BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 25196359)

  • 1. Allosteric inhibitors of calpains: Reevaluating inhibition by PD150606 and LSEAL.
    Low KE; Karunan Partha S; Davies PL; Campbell RL
    Biochim Biophys Acta; 2014 Dec; 1840(12):3367-73. PubMed ID: 25196359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insertion sequence 1 from calpain-3 is functional in calpain-2 as an internal propeptide.
    McCartney CE; Ye Q; Campbell RL; Davies PL
    J Biol Chem; 2018 Nov; 293(46):17716-17730. PubMed ID: 30254072
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space.
    Kalash L; Cresser-Brown J; Habchi J; Morgan C; Miller DJ; Glen RC; Allemann RK; Bender A
    Eur J Med Chem; 2018 Sep; 157():1264-1275. PubMed ID: 30195237
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of calpain-3 penta-EF-hand (PEF) domain - a homodimerized PEF family member with calcium bound at the fifth EF-hand.
    Partha SK; Ravulapalli R; Allingham JS; Campbell RL; Davies PL
    FEBS J; 2014 Jul; 281(14):3138-49. PubMed ID: 24846670
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains.
    Moldoveanu T; Gehring K; Green DR
    Nature; 2008 Nov; 456(7220):404-8. PubMed ID: 19020622
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-function relationships in calpains.
    Campbell RL; Davies PL
    Biochem J; 2012 Nov; 447(3):335-51. PubMed ID: 23035980
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin.
    Hanna RA; Campbell RL; Davies PL
    Nature; 2008 Nov; 456(7220):409-12. PubMed ID: 19020623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
    Todd B; Moore D; Deivanayagam CC; Lin GD; Chattopadhyay D; Maki M; Wang KK; Narayana SV
    J Mol Biol; 2003 Apr; 328(1):131-46. PubMed ID: 12684003
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of calpain-mediated cell death by a novel peptide inhibitor.
    McCollum AT; Jafarifar F; Lynn BC; Agu RU; Stinchcomb AL; Wang S; Chen Q; Guttmann RP
    Exp Neurol; 2006 Dec; 202(2):506-13. PubMed ID: 16956607
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.
    Wang KK; Nath R; Posner A; Raser KJ; Buroker-Kilgore M; Hajimohammadreza I; Probert A W; Marcoux FW; Ye Q; Takano E; Hatanaka M; Maki M; Caner H; Collins JL; Fergus A; Lee KS; Lunney EA; Hays SJ; Yuen P
    Proc Natl Acad Sci U S A; 1996 Jun; 93(13):6687-92. PubMed ID: 8692879
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinguishing between calpain heterodimerization and homodimerization.
    Ravulapalli R; Campbell RL; Gauthier SY; Dhe-Paganon S; Davies PL
    FEBS J; 2009 Feb; 276(4):973-82. PubMed ID: 19215300
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Ca(2+) switch aligns the active site of calpain.
    Moldoveanu T; Hosfield CM; Lim D; Elce JS; Jia Z; Davies PL
    Cell; 2002 Mar; 108(5):649-60. PubMed ID: 11893336
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction of calpastatin with calpain: a review.
    Wendt A; Thompson VF; Goll DE
    Biol Chem; 2004 Jun; 385(6):465-72. PubMed ID: 15255177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evolutionary and physical linkage between calpains and penta-EF-hand Ca2+-binding proteins.
    Maki M; Maemoto Y; Osako Y; Shibata H
    FEBS J; 2012 Apr; 279(8):1414-21. PubMed ID: 22404899
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calpastatin simultaneously binds four calpains with different kinetic constants.
    Hanna RA; Garcia-Diaz BE; Davies PL
    FEBS Lett; 2007 Jun; 581(16):2894-8. PubMed ID: 17543955
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NMR structural characterization of the penta-peptide calpain inhibitor.
    Deshmukh L; Wu L; Guttmann RP; Vinogradova O
    FEBS Lett; 2009 Jan; 583(1):135-40. PubMed ID: 19059407
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding.
    Lin GD; Chattopadhyay D; Maki M; Wang KK; Carson M; Jin L; Yuen PW; Takano E; Hatanaka M; DeLucas LJ; Narayana SV
    Nat Struct Biol; 1997 Jul; 4(7):539-47. PubMed ID: 9228946
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Calpastatin has two distinct sites for interaction with calpain--effect of calpastatin fragments on the binding of calpain to membranes.
    Kawasaki H; Emori Y; Suzuki K
    Arch Biochem Biophys; 1993 Sep; 305(2):467-72. PubMed ID: 8373185
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a novel calpain inhibitor using phage display.
    Guttmann RP; Day GA; Wang X; Bottiggi KA
    Biochem Biophys Res Commun; 2005 Aug; 333(4):1087-92. PubMed ID: 15979564
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition.
    Davis TL; Walker JR; Finerty PJ; Mackenzie F; Newman EM; Dhe-Paganon S
    J Mol Biol; 2007 Feb; 366(1):216-29. PubMed ID: 17157313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.