296 related articles for article (PubMed ID: 25197067)
21. Assays to Study Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (PHD2), a Key Human Oxygen Sensing Protein.
Chan YY; Mbenza NM; Chan MC; Leung IKH
Methods Mol Biol; 2023; 2648():187-206. PubMed ID: 37039992
[TBL] [Abstract][Full Text] [Related]
22. Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
Flashman E; Davies SL; Yeoh KK; Schofield CJ
Biochem J; 2010 Mar; 427(1):135-42. PubMed ID: 20055761
[TBL] [Abstract][Full Text] [Related]
23. Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio- and stereoselectivity of prolyl hydroxylases.
Horita S; Scotti JS; Thinnes C; Mottaghi-Taromsari YS; Thalhammer A; Ge W; Aik W; Loenarz C; Schofield CJ; McDonough MA
Structure; 2015 Apr; 23(4):639-52. PubMed ID: 25728928
[TBL] [Abstract][Full Text] [Related]
24. Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
McDonough MA; Li V; Flashman E; Chowdhury R; Mohr C; Liénard BM; Zondlo J; Oldham NJ; Clifton IJ; Lewis J; McNeill LA; Kurzeja RJ; Hewitson KS; Yang E; Jordan S; Syed RS; Schofield CJ
Proc Natl Acad Sci U S A; 2006 Jun; 103(26):9814-9. PubMed ID: 16782814
[TBL] [Abstract][Full Text] [Related]
25. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
26. Mechanism of Molecular Oxygen Diffusion in a Hypoxia-Sensing Prolyl Hydroxylase Using Multiscale Simulation.
Domene C; Jorgensen C; Schofield CJ
J Am Chem Soc; 2020 Feb; 142(5):2253-2263. PubMed ID: 31939292
[TBL] [Abstract][Full Text] [Related]
27. Microbiota-derived butyrate is an endogenous HIF prolyl hydroxylase inhibitor.
Wang RX; Henen MA; Lee JS; Vögeli B; Colgan SP
Gut Microbes; 2021; 13(1):1938380. PubMed ID: 34190032
[TBL] [Abstract][Full Text] [Related]
28. The roles and signaling pathways of prolyl-4-hydroxylase 2 in the tumor microenvironment.
Li A; Zhang Y; Wang Z; Dong H; Fu N; Han X
Chem Biol Interact; 2019 Apr; 303():40-49. PubMed ID: 30817904
[TBL] [Abstract][Full Text] [Related]
29. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
[TBL] [Abstract][Full Text] [Related]
30. Biochemistry of the hypoxia-inducible factor hydroxylases.
Fiorini G; Schofield CJ
Curr Opin Chem Biol; 2024 Apr; 79():102428. PubMed ID: 38330792
[TBL] [Abstract][Full Text] [Related]
31. Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
Flashman E; Hoffart LM; Hamed RB; Bollinger JM; Krebs C; Schofield CJ
FEBS J; 2010 Oct; 277(19):4089-99. PubMed ID: 20840591
[TBL] [Abstract][Full Text] [Related]
32. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
[TBL] [Abstract][Full Text] [Related]
33. Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal
Lippl K; Boleininger A; McDonough MA; Abboud MI; Tarhonskaya H; Chowdhury R; Loenarz C; Schofield CJ
Hypoxia (Auckl); 2018; 6():57-71. PubMed ID: 30519597
[TBL] [Abstract][Full Text] [Related]
34. Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression.
Stockmann C; Fandrey J
Clin Exp Pharmacol Physiol; 2006 Oct; 33(10):968-79. PubMed ID: 17002676
[TBL] [Abstract][Full Text] [Related]
35. Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.
Ehrismann D; Flashman E; Genn DN; Mathioudakis N; Hewitson KS; Ratcliffe PJ; Schofield CJ
Biochem J; 2007 Jan; 401(1):227-34. PubMed ID: 16952279
[TBL] [Abstract][Full Text] [Related]
36. Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases.
Chowdhury R; Candela-Lena JI; Chan MC; Greenald DJ; Yeoh KK; Tian YM; McDonough MA; Tumber A; Rose NR; Conejo-Garcia A; Demetriades M; Mathavan S; Kawamura A; Lee MK; van Eeden F; Pugh CW; Ratcliffe PJ; Schofield CJ
ACS Chem Biol; 2013 Jul; 8(7):1488-96. PubMed ID: 23683440
[TBL] [Abstract][Full Text] [Related]
37. Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation.
Kageyama Y; Koshiji M; To KK; Tian YM; Ratcliffe PJ; Huang LE
FASEB J; 2004 Jun; 18(9):1028-30. PubMed ID: 15084514
[TBL] [Abstract][Full Text] [Related]
38. Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases.
Markolovic S; Wilkins SE; Schofield CJ
J Biol Chem; 2015 Aug; 290(34):20712-20722. PubMed ID: 26152730
[TBL] [Abstract][Full Text] [Related]
39. Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites.
Pappalardi MB; McNulty DE; Martin JD; Fisher KE; Jiang Y; Burns MC; Zhao H; Ho T; Sweitzer S; Schwartz B; Annan RS; Copeland RA; Tummino PJ; Luo L
Biochem J; 2011 Jun; 436(2):363-9. PubMed ID: 21410436
[TBL] [Abstract][Full Text] [Related]
40. Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.
Chan DA; Sutphin PD; Yen SE; Giaccia AJ
Mol Cell Biol; 2005 Aug; 25(15):6415-26. PubMed ID: 16024780
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]