These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 2519721)

  • 1. Analysis for N2-(pyridyloxobutyl)deoxyguanosine adducts in DNA of tissues exposed to tritium-labeled 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.
    Spratt TE; Trushin N; Lin D; Hecht SS
    Chem Res Toxicol; 1989; 2(3):169-73. PubMed ID: 2519721
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Formation of hemoglobin adducts upon treatment of F344 rats with the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.
    Carmella SG; Hecht SS
    Cancer Res; 1987 May; 47(10):2626-30. PubMed ID: 3567895
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of cysteine adduct formation in rat hemoglobin by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and related compounds.
    Carmella SG; Kagan SS; Spratt TE; Hecht SS
    Cancer Res; 1990 Sep; 50(17):5453-9. PubMed ID: 2201436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured F344 rat oral tissue and esophagus.
    Murphy SE; Heiblum R; Trushin N
    Cancer Res; 1990 Aug; 50(15):4685-91. PubMed ID: 2369743
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens.
    Wang M; Cheng G; Sturla SJ; Shi Y; McIntee EJ; Villalta PW; Upadhyaya P; Hecht SS
    Chem Res Toxicol; 2003 May; 16(5):616-26. PubMed ID: 12755591
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM; Kenney PM; Peterson LA
    Chem Res Toxicol; 2003 Jan; 16(1):1-6. PubMed ID: 12693024
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.
    Lao Y; Villalta PW; Sturla SJ; Wang M; Hecht SS
    Chem Res Toxicol; 2006 May; 19(5):674-82. PubMed ID: 16696570
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evidence for 4-(3-pyridyl)-4-oxobutylation of DNA in F344 rats treated with the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.
    Hecht SS; Spratt TE; Trushin N
    Carcinogenesis; 1988 Jan; 9(1):161-5. PubMed ID: 3335041
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Upadhyaya P; Kalscheuer S; Hochalter JB; Villalta PW; Hecht SS
    Chem Res Toxicol; 2008 Jul; 21(7):1468-76. PubMed ID: 18570389
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA adduct formation from tobacco-specific N-nitrosamines.
    Hecht SS
    Mutat Res; 1999 Mar; 424(1-2):127-42. PubMed ID: 10064856
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantitation of pyridyloxobutyl DNA adducts in nasal and oral mucosa of rats treated chronically with enantiomers of N'-nitrosonornicotine.
    Zhang S; Wang M; Villalta PW; Lindgren BR; Lao Y; Hecht SS
    Chem Res Toxicol; 2009 May; 22(5):949-56. PubMed ID: 19405515
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
    Zhang S; Wang M; Villalta PW; Lindgren BR; Upadhyaya P; Lao Y; Hecht SS
    Chem Res Toxicol; 2009 May; 22(5):926-36. PubMed ID: 19358518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA.
    Hecht SS; Villalta PW; Sturla SJ; Cheng G; Yu N; Upadhyaya P; Wang M
    Chem Res Toxicol; 2004 May; 17(5):588-97. PubMed ID: 15144215
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study.
    Zhao L; Balbo S; Wang M; Upadhyaya P; Khariwala SS; Villalta PW; Hecht SS
    Chem Res Toxicol; 2013 Oct; 26(10):1526-35. PubMed ID: 24001146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism and DNA single strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its analogues in primary culture of rat hepatocytes.
    Liu LL; Alaoui-Jamali MA; el Alami N; Castonguay A
    Cancer Res; 1990 Mar; 50(6):1810-6. PubMed ID: 2306734
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.
    Balbo S; Johnson CS; Kovi RC; James-Yi SA; O'Sullivan MG; Wang M; Le CT; Khariwala SS; Upadhyaya P; Hecht SS
    Carcinogenesis; 2014 Dec; 35(12):2798-806. PubMed ID: 25269804
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence supporting the role of DNA pyridyloxobutylation in rat nasal carcinogenesis by tobacco-specific nitrosamines.
    Trushin N; Rivenson A; Hecht SS
    Cancer Res; 1994 Mar; 54(5):1205-11. PubMed ID: 8118807
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stereoselective metabolism of nicotine and tobacco-specific N-nitrosamines to 4-hydroxy-4-(3-pyridyl)butanoic acid in rats.
    Trushin N; Hecht SS
    Chem Res Toxicol; 1999 Feb; 12(2):164-71. PubMed ID: 10027794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of pyridyloxobutyl DNA adducts in F344 rats chronically treated with (R)- and (S)-N'-nitrosonornicotine.
    Lao Y; Yu N; Kassie F; Villalta PW; Hecht SS
    Chem Res Toxicol; 2007 Feb; 20(2):246-56. PubMed ID: 17305408
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of an
    Li Y; Hecht SS
    Chem Res Toxicol; 2021 Apr; 34(4):992-1003. PubMed ID: 33705110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.