182 related articles for article (PubMed ID: 2519721)
21. Stable isotope labeling-mass spectrometry analysis of methyl- and pyridyloxobutyl-guanine adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in p53-derived DNA sequences.
Rajesh M; Wang G; Jones R; Tretyakova N
Biochemistry; 2005 Feb; 44(6):2197-207. PubMed ID: 15697245
[TBL] [Abstract][Full Text] [Related]
22. Evidence that a hemoglobin adduct of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a 4-(3-pyridyl)-4-oxobutyl carboxylic acid ester.
Carmella SG; Kagan SS; Hecht SS
Chem Res Toxicol; 1992; 5(1):76-80. PubMed ID: 1581541
[TBL] [Abstract][Full Text] [Related]
23. Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.
Belinsky SA; White CM; Trushin N; Hecht SS
Carcinogenesis; 1989 Dec; 10(12):2269-74. PubMed ID: 2591016
[TBL] [Abstract][Full Text] [Related]
24. Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Lao Y; Yu N; Kassie F; Villalta PW; Hecht SS
Chem Res Toxicol; 2007 Feb; 20(2):235-45. PubMed ID: 17305407
[TBL] [Abstract][Full Text] [Related]
25. Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase.
Wang L; Spratt TE; Liu XK; Hecht SS; Pegg AE; Peterson LA
Chem Res Toxicol; 1997 May; 10(5):562-7. PubMed ID: 9168254
[TBL] [Abstract][Full Text] [Related]
26. DNA and hemoglobin alkylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
Hecht SS; Trushin N
Carcinogenesis; 1988 Sep; 9(9):1665-8. PubMed ID: 3409470
[TBL] [Abstract][Full Text] [Related]
27. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
Staretz ME; Foiles PG; Miglietta LM; Hecht SS
Cancer Res; 1997 Jan; 57(2):259-66. PubMed ID: 9000565
[TBL] [Abstract][Full Text] [Related]
28. Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Stepanov I; Hecht SS
Chem Res Toxicol; 2009 Feb; 22(2):406-14. PubMed ID: 19166332
[TBL] [Abstract][Full Text] [Related]
29. Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.
Li Y; Ma B; Cao Q; Balbo S; Zhao L; Upadhyaya P; Hecht SS
Chem Res Toxicol; 2019 Apr; 32(4):773-783. PubMed ID: 30740971
[TBL] [Abstract][Full Text] [Related]
30. Measurement of O6-methyldeoxyguanosine in DNA methylated by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone using a biotin-avidin enzyme-linked immunosorbent assay.
Foiles PG; Trushin N; Castonguay A
Carcinogenesis; 1985 Jul; 6(7):989-93. PubMed ID: 4017179
[TBL] [Abstract][Full Text] [Related]
31. Two types of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone hemoglobin adducts, from metabolites which migrate into or are formed in red blood cells.
Murphy SE; Coletta KA
Cancer Res; 1993 Feb; 53(4):777-83. PubMed ID: 8428358
[TBL] [Abstract][Full Text] [Related]
32. Study of DNA methylation by tobacco-specific N-nitrosamines.
Castonguay A; Foiles PG; Trushin N; Hecht SS
Environ Health Perspect; 1985 Oct; 62():197-202. PubMed ID: 4085424
[TBL] [Abstract][Full Text] [Related]
33. Effect of nicotine and tobacco-specific nitrosamines on the metabolism of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by rat oral tissue.
Murphy SE; Heiblum R
Carcinogenesis; 1990 Sep; 11(9):1663-6. PubMed ID: 2205411
[TBL] [Abstract][Full Text] [Related]
34. Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Sturla SJ; Scott J; Lao Y; Hecht SS; Villalta PW
Chem Res Toxicol; 2005 Jun; 18(6):1048-55. PubMed ID: 15962940
[TBL] [Abstract][Full Text] [Related]
35. Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine in Syrian golden hamsters.
Hoffmann D; Castonguay A; Rivenson A; Hecht SS
Cancer Res; 1981 Jun; 41(6):2386-93. PubMed ID: 7237437
[TBL] [Abstract][Full Text] [Related]
36. In vivo and in vitro persistence of pyridyloxobutyl DNA adducts from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Peterson LA; Mathew R; B1P6Murphy SE; Trushin N; Hecht SS
Carcinogenesis; 1991 Nov; 12(11):2069-72. PubMed ID: 1934291
[TBL] [Abstract][Full Text] [Related]
37. Solvolysis of model compounds for alpha-hydroxylation of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: evidence for a cyclic oxonium ion intermediate in the alkylation of nucleophiles.
Spratt TE; Peterson LA; Confer WL; Hecht SS
Chem Res Toxicol; 1990; 3(4):350-6. PubMed ID: 2133084
[TBL] [Abstract][Full Text] [Related]
38. Modulation of DNA repair by various inhibitors of DNA synthesis following 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induced DNA damage.
Cloutier JF; Castonguay A
Chem Biol Interact; 1998 Mar; 110(1-2):7-25. PubMed ID: 9566722
[TBL] [Abstract][Full Text] [Related]
39. Mass Spectrometric Quantitation of Apurinic/Apyrimidinic Sites in Tissue DNA of Rats Exposed to Tobacco-Specific Nitrosamines and in Lung and Leukocyte DNA of Cigarette Smokers and Nonsmokers.
Guo J; Chen H; Upadhyaya P; Zhao Y; Turesky RJ; Hecht SS
Chem Res Toxicol; 2020 Sep; 33(9):2475-2486. PubMed ID: 32833447
[TBL] [Abstract][Full Text] [Related]
40. Identification of adducts produced by the reaction of 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanol with deoxyguanosine and DNA.
Upadhyaya P; Sturla SJ; Tretyakova N; Ziegel R; Villalta PW; Wang M; Hecht SS
Chem Res Toxicol; 2003 Feb; 16(2):180-90. PubMed ID: 12588189
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
