BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

700 related articles for article (PubMed ID: 25201414)

  • 1. Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.
    Ghezraoui H; Piganeau M; Renouf B; Renaud JB; Sallmyr A; Ruis B; Oh S; Tomkinson AE; Hendrickson EA; Giovannangeli C; Jasin M; Brunet E
    Mol Cell; 2014 Sep; 55(6):829-842. PubMed ID: 25201414
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation.
    Simsek D; Brunet E; Wong SY; Katyal S; Gao Y; McKinnon PJ; Lou J; Zhang L; Li J; Rebar EJ; Gregory PD; Holmes MC; Jasin M
    PLoS Genet; 2011 Jun; 7(6):e1002080. PubMed ID: 21655080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation.
    Simsek D; Jasin M
    Nat Struct Mol Biol; 2010 Apr; 17(4):410-6. PubMed ID: 20208544
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells.
    Soni A; Siemann M; Pantelias GE; Iliakis G
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Nov; 793():2-8. PubMed ID: 26520366
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.
    Boboila C; Jankovic M; Yan CT; Wang JH; Wesemann DR; Zhang T; Fazeli A; Feldman L; Nussenzweig A; Nussenzweig M; Alt FW
    Proc Natl Acad Sci U S A; 2010 Feb; 107(7):3034-9. PubMed ID: 20133803
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics.
    Kumari N; Antil H; Kumari S; Raghavan SC
    Genomics; 2023 Nov; 115(6):110731. PubMed ID: 37871849
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining.
    Lu G; Duan J; Shu S; Wang X; Gao L; Guo J; Zhang Y
    Proc Natl Acad Sci U S A; 2016 Feb; 113(5):1256-60. PubMed ID: 26787905
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.
    Park J; Welner RS; Chan MY; Troppito L; Staber PB; Tenen DG; Yan CT
    J Immunol; 2016 Jan; 196(1):244-55. PubMed ID: 26608917
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Repair of double-strand breaks by end joining.
    Chiruvella KK; Liang Z; Wilson TE
    Cold Spring Harb Perspect Biol; 2013 May; 5(5):a012757. PubMed ID: 23637284
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IgH class switching and translocations use a robust non-classical end-joining pathway.
    Yan CT; Boboila C; Souza EK; Franco S; Hickernell TR; Murphy M; Gumaste S; Geyer M; Zarrin AA; Manis JP; Rajewsky K; Alt FW
    Nature; 2007 Sep; 449(7161):478-82. PubMed ID: 17713479
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.
    Sharpless NE; Ferguson DO; O'Hagan RC; Castrillon DH; Lee C; Farazi PA; Alson S; Fleming J; Morton CC; Frank K; Chin L; Alt FW; DePinho RA
    Mol Cell; 2001 Dec; 8(6):1187-96. PubMed ID: 11779495
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
    Soni A; Siemann M; Grabos M; Murmann T; Pantelias GE; Iliakis G
    Nucleic Acids Res; 2014 Jun; 42(10):6380-92. PubMed ID: 24748665
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Time-dependent predominance of nonhomologous DNA end-joining pathways during embryonic development in mice.
    Chiruvella KK; Sebastian R; Sharma S; Karande AA; Choudhary B; Raghavan SC
    J Mol Biol; 2012 Mar; 417(3):197-211. PubMed ID: 22306462
    [TBL] [Abstract][Full Text] [Related]  

  • 14. C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin.
    Liu S; Liu X; Kamdar RP; Wanotayan R; Sharma MK; Adachi N; Matsumoto Y
    Biochem Biophys Res Commun; 2013 Sep; 439(2):173-8. PubMed ID: 23994631
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA-PKcs suppresses illegitimate chromosome rearrangements.
    Wang J; Sadeghi CA; Frock RL
    Nucleic Acids Res; 2024 May; 52(9):5048-5066. PubMed ID: 38412274
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Homology and enzymatic requirements of microhomology-dependent alternative end joining.
    Sharma S; Javadekar SM; Pandey M; Srivastava M; Kumari R; Raghavan SC
    Cell Death Dis; 2015 Mar; 6(3):e1697. PubMed ID: 25789972
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding.
    Chiruvella KK; Renard BM; Birkeland SR; Sunder S; Liang Z; Wilson TE
    DNA Repair (Amst); 2014 Dec; 24():37-45. PubMed ID: 25457772
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.
    Boboila C; Yan C; Wesemann DR; Jankovic M; Wang JH; Manis J; Nussenzweig A; Nussenzweig M; Alt FW
    J Exp Med; 2010 Feb; 207(2):417-27. PubMed ID: 20142431
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cadmium delays non-homologous end joining (NHEJ) repair via inhibition of DNA-PKcs phosphorylation and downregulation of XRCC4 and Ligase IV.
    Li W; Gu X; Zhang X; Kong J; Ding N; Qi Y; Zhang Y; Wang J; Huang D
    Mutat Res; 2015 Sep; 779():112-23. PubMed ID: 26201248
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1).
    Boboila C; Oksenych V; Gostissa M; Wang JH; Zha S; Zhang Y; Chai H; Lee CS; Jankovic M; Saez LM; Nussenzweig MC; McKinnon PJ; Alt FW; Schwer B
    Proc Natl Acad Sci U S A; 2012 Feb; 109(7):2473-8. PubMed ID: 22308491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.