These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

384 related articles for article (PubMed ID: 25204433)

  • 1. Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.
    Trausch-Azar JS; Abed M; Orian A; Schwartz AL
    J Cell Physiol; 2015 Apr; 230(4):842-52. PubMed ID: 25204433
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB; Dodard-Friedman I; Blank V
    J Biol Chem; 2015 Oct; 290(43):26292-302. PubMed ID: 26306035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.
    Bhaskaran N; van Drogen F; Ng HF; Kumar R; Ekholm-Reed S; Peter M; Sangfelt O; Reed SI
    Mol Cell Biol; 2013 Jan; 33(1):85-97. PubMed ID: 23109421
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
    Welcker M; Orian A; Grim JE; Eisenman RN; Clurman BE
    Curr Biol; 2004 Oct; 14(20):1852-7. PubMed ID: 15498494
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T; Hattori T; Kitagawa K; Uchida C; Kotake Y; Kosugi I; Oda T; Kitagawa M
    J Biol Chem; 2009 Oct; 284(41):27766-27779. PubMed ID: 19679664
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis.
    Olson BL; Hock MB; Ekholm-Reed S; Wohlschlegel JA; Dev KK; Kralli A; Reed SI
    Genes Dev; 2008 Jan; 22(2):252-64. PubMed ID: 18198341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
    Biswas M; Phan D; Watanabe M; Chan JY
    J Biol Chem; 2011 Nov; 286(45):39282-9. PubMed ID: 21953459
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ubiquitin ligase Fbw7 restricts the replication of hepatitis C virus by targeting NS5B for ubiquitination and degradation.
    Chen J; Wu X; Chen S; Chen S; Xiang N; Chen Y; Guo D
    Biochem Biophys Res Commun; 2016 Feb; 470(3):697-703. PubMed ID: 26774344
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway.
    Spagnol V; Oliveira CAB; Randle SJ; Passos PMS; Correia CRSTB; Simaroli NB; Oliveira JS; Mevissen TET; Medeiros AC; Gomes MD; Komander D; Laman H; Teixeira FR
    Biochim Biophys Acta Gen Subj; 2021 Jan; 1865(1):129754. PubMed ID: 33010352
    [TBL] [Abstract][Full Text] [Related]  

  • 11. E3 Ubiquitin Ligase Fbw7 Negatively Regulates Osteoblast Differentiation by Targeting Runx2 for Degradation.
    Kumar Y; Kapoor I; Khan K; Thacker G; Khan MP; Shukla N; Kanaujiya JK; Sanyal S; Chattopadhyay N; Trivedi AK
    J Biol Chem; 2015 Dec; 290(52):30975-87. PubMed ID: 26542806
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The stomatin-like protein SLP-1 and Cdk2 interact with the F-Box protein Fbw7-γ.
    Zhang W; MacDonald EM; Koepp DM
    PLoS One; 2012; 7(10):e47736. PubMed ID: 23082202
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Physiological Functions of FBW7 in Metabolism.
    Zhang J; Kong DH; Huang X; Yu R; Yang Y
    Horm Metab Res; 2022 May; 54(5):280-287. PubMed ID: 35533672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
    Wang JY; Zhu B; Patterson LL; Rogan MR; Kibler CE; McBride JW
    PLoS Pathog; 2020 Apr; 16(4):e1008541. PubMed ID: 32353058
    [TBL] [Abstract][Full Text] [Related]  

  • 15. E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
    Lochab S; Pal P; Kapoor I; Kanaujiya JK; Sanyal S; Behre G; Trivedi AK
    Biochim Biophys Acta; 2013 Dec; 1833(12):2639-2652. PubMed ID: 23820376
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
    Liu N; Li H; Li S; Shen M; Xiao N; Chen Y; Wang Y; Wang W; Wang R; Wang Q; Sun J; Wang P
    J Biol Chem; 2010 Jun; 285(24):18858-67. PubMed ID: 20388706
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.
    Grim JE; Gustafson MP; Hirata RK; Hagar AC; Swanger J; Welcker M; Hwang HC; Ericsson J; Russell DW; Clurman BE
    J Cell Biol; 2008 Jun; 181(6):913-20. PubMed ID: 18559665
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The F-box protein FBXL16 up-regulates the stability of C-MYC oncoprotein by antagonizing the activity of the F-box protein FBW7.
    Morel M; Shah KN; Long W
    J Biol Chem; 2020 Jun; 295(23):7970-7980. PubMed ID: 32345600
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RNF34 is a cold-regulated E3 ubiquitin ligase for PGC-1α and modulates brown fat cell metabolism.
    Wei P; Pan D; Mao C; Wang YX
    Mol Cell Biol; 2012 Jan; 32(2):266-75. PubMed ID: 22064484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M; Orian A; Jin J; Grim JE; Harper JW; Eisenman RN; Clurman BE
    Proc Natl Acad Sci U S A; 2004 Jun; 101(24):9085-90. PubMed ID: 15150404
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.