BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

274 related articles for article (PubMed ID: 25210038)

  • 1. New insights about enzyme evolution from large scale studies of sequence and structure relationships.
    Brown SD; Babbitt PC
    J Biol Chem; 2014 Oct; 289(44):30221-30228. PubMed ID: 25210038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evolution of Enzyme Superfamilies: Comprehensive Exploration of Sequence-Function Relationships.
    Baier F; Copp JN; Tokuriki N
    Biochemistry; 2016 Nov; 55(46):6375-6388. PubMed ID: 27802036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A global view of structure-function relationships in the tautomerase superfamily.
    Davidson R; Baas BJ; Akiva E; Holliday GL; Polacco BJ; LeVieux JA; Pullara CR; Zhang YJ; Whitman CP; Babbitt PC
    J Biol Chem; 2018 Feb; 293(7):2342-2357. PubMed ID: 29184004
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies.
    Chiang RA; Sali A; Babbitt PC
    PLoS Comput Biol; 2008 Aug; 4(8):e1000142. PubMed ID: 18670595
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies.
    Furnham N; Dawson NL; Rahman SA; Thornton JM; Orengo CA
    J Mol Biol; 2016 Jan; 428(2 Pt A):253-267. PubMed ID: 26585402
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain.
    Holliday GL; Akiva E; Meng EC; Brown SD; Calhoun S; Pieper U; Sali A; Booker SJ; Babbitt PC
    Methods Enzymol; 2018; 606():1-71. PubMed ID: 30097089
    [TBL] [Abstract][Full Text] [Related]  

  • 7. To what extent do structural changes in catalytic metal sites affect enzyme function?
    Valasatava Y; Rosato A; Furnham N; Thornton JM; Andreini C
    J Inorg Biochem; 2018 Feb; 179():40-53. PubMed ID: 29161638
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies.
    Furnham N; Sillitoe I; Holliday GL; Cuff AL; Laskowski RA; Orengo CA; Thornton JM
    PLoS Comput Biol; 2012; 8(3):e1002403. PubMed ID: 22396634
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalysing new reactions during evolution: economy of residues and mechanism.
    Bartlett GJ; Borkakoti N; Thornton JM
    J Mol Biol; 2003 Aug; 331(4):829-60. PubMed ID: 12909013
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Topological variation in the evolution of new reactions in functionally diverse enzyme superfamilies.
    Meng EC; Babbitt PC
    Curr Opin Struct Biol; 2011 Jun; 21(3):391-7. PubMed ID: 21458983
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular dynamics explorations of active site structure in designed and evolved enzymes.
    Osuna S; Jiménez-Osés G; Noey EL; Houk KN
    Acc Chem Res; 2015 Apr; 48(4):1080-9. PubMed ID: 25738880
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Divergence and convergence in enzyme evolution.
    Galperin MY; Koonin EV
    J Biol Chem; 2012 Jan; 287(1):21-28. PubMed ID: 22069324
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Common Structural Core of Three-Dozen Residues Reveals Intersuperfamily Relationships.
    Mönttinen HA; Ravantti JJ; Poranen MM
    Mol Biol Evol; 2016 Jul; 33(7):1697-710. PubMed ID: 26931141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enzyme promiscuity: engine of evolutionary innovation.
    Pandya C; Farelli JD; Dunaway-Mariano D; Allen KN
    J Biol Chem; 2014 Oct; 289(44):30229-30236. PubMed ID: 25210039
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution of function in protein superfamilies, from a structural perspective.
    Todd AE; Orengo CA; Thornton JM
    J Mol Biol; 2001 Apr; 307(4):1113-43. PubMed ID: 11286560
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Understanding the importance of protein structure to nature's routes for divergent evolution in TIM barrel enzymes.
    Wise EL; Rayment I
    Acc Chem Res; 2004 Mar; 37(3):149-58. PubMed ID: 15023082
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily.
    Akiva E; Copp JN; Tokuriki N; Babbitt PC
    Proc Natl Acad Sci U S A; 2017 Nov; 114(45):E9549-E9558. PubMed ID: 29078300
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Introduction to the thematic minireview series on enzyme evolution.
    Banerjee R
    J Biol Chem; 2014 Oct; 289(44):30196-30197. PubMed ID: 25210045
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deep evolutionary analysis reveals the design principles of fold A glycosyltransferases.
    Taujale R; Venkat A; Huang LC; Zhou Z; Yeung W; Rasheed KM; Li S; Edison AS; Moremen KW; Kannan N
    Elife; 2020 Apr; 9():. PubMed ID: 32234211
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enzyme recruitment and its role in metabolic expansion.
    Schulenburg C; Miller BG
    Biochemistry; 2014 Feb; 53(5):836-45. PubMed ID: 24483367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.