BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

511 related articles for article (PubMed ID: 25215604)

  • 1. Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients.
    Fang YS; Tsai KJ; Chang YJ; Kao P; Woods R; Kuo PH; Wu CC; Liao JY; Chou SC; Lin V; Jin LW; Yuan HS; Cheng IH; Tu PH; Chen YR
    Nat Commun; 2014 Sep; 5():4824. PubMed ID: 25215604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Annexin A11 aggregation in FTLD-TDP type C and related neurodegenerative disease proteinopathies.
    Robinson JL; Suh E; Xu Y; Hurtig HI; Elman L; McMillan CT; Irwin DJ; Porta S; Van Deerlin VM; Lee EB
    Acta Neuropathol; 2024 Jun; 147(1):104. PubMed ID: 38896345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage.
    Chiang WC; Fang YS; Lye YS; Weng TY; Ganesan K; Huang SH; Chang LY; Chou SC; Chen YR
    ACS Chem Neurosci; 2022 Sep; 13(17):2599-2612. PubMed ID: 36007056
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.
    Montalbano M; McAllen S; Cascio FL; Sengupta U; Garcia S; Bhatt N; Ellsworth A; Heidelman EA; Johnson OD; Doskocil S; Kayed R
    Neurobiol Dis; 2020 Dec; 146():105130. PubMed ID: 33065281
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antibody against TDP-43 phosphorylated at serine 375 suggests conformational differences of TDP-43 aggregates among FTLD-TDP subtypes.
    Neumann M; Frick P; Paron F; Kosten J; Buratti E; Mackenzie IR
    Acta Neuropathol; 2020 Nov; 140(5):645-658. PubMed ID: 32778941
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Full-length TDP-43 and its C-terminal domain form filaments
    Capitini C; Fani G; Vivoli Vega M; Penco A; Canale C; Cabrita LD; Calamai M; Christodoulou J; Relini A; Chiti F
    Amyloid; 2021 Mar; 28(1):56-65. PubMed ID: 33026249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP.
    Kao PF; Chen YR; Liu XB; DeCarli C; Seeley WW; Jin LW
    Ann Neurol; 2015 Aug; 78(2):211-21. PubMed ID: 25921485
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage.
    Kumar ST; Nazarov S; Porta S; Maharjan N; Cendrowska U; Kabani M; Finamore F; Xu Y; Lee VM; Lashuel HA
    Nat Neurosci; 2023 Jun; 26(6):983-996. PubMed ID: 37248338
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.
    Ratti A; Buratti E
    J Neurochem; 2016 Aug; 138 Suppl 1():95-111. PubMed ID: 27015757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylated TAR DNA-binding protein-43: Aggregation and antibody-based inhibition.
    Esposto JC; Martic S
    Biochim Biophys Acta Mol Basis Dis; 2021 Dec; 1867(12):166234. PubMed ID: 34339840
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.
    Miguel L; Frébourg T; Campion D; Lecourtois M
    Neurobiol Dis; 2011 Feb; 41(2):398-406. PubMed ID: 20951205
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects.
    Langellotti S; Romano V; Romano G; Klima R; Feiguin F; Cragnaz L; Romano M; Baralle FE
    Dis Model Mech; 2016 Jun; 9(6):659-69. PubMed ID: 27101846
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy.
    Chen HJ; Topp SD; Hui HS; Zacco E; Katarya M; McLoughlin C; King A; Smith BN; Troakes C; Pastore A; Shaw CE
    Brain; 2019 Dec; 142(12):3753-3770. PubMed ID: 31605140
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of TDP-43 Proteinopathy Onset and Propagation.
    Chen HJ; Mitchell JC
    Int J Mol Sci; 2021 Jun; 22(11):. PubMed ID: 34199367
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution.
    Zhu L; Xu M; Yang M; Yang Y; Li Y; Deng J; Ruan L; Liu J; Du S; Liu X; Feng W; Fushimi K; Bigio EH; Mesulam M; Wang C; Wu JY
    Hum Mol Genet; 2014 Dec; 23(25):6863-77. PubMed ID: 25113748
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Perfusion alterations converge with patterns of pathological spread in transactive response DNA-binding protein 43 proteinopathies.
    Ferraro PM; Jester C; Olm CA; Placek K; Agosta F; Elman L; McCluskey L; Irwin DJ; Detre JA; Filippi M; Grossman M; McMillan CT
    Neurobiol Aging; 2018 Aug; 68():85-92. PubMed ID: 29751289
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils.
    Shimonaka S; Nonaka T; Suzuki G; Hisanaga S; Hasegawa M
    J Biol Chem; 2016 Apr; 291(17):8896-907. PubMed ID: 26887947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Neumann M; Sampathu DM; Kwong LK; Truax AC; Micsenyi MC; Chou TT; Bruce J; Schuck T; Grossman M; Clark CM; McCluskey LF; Miller BL; Masliah E; Mackenzie IR; Feldman H; Feiden W; Kretzschmar HA; Trojanowski JQ; Lee VM
    Science; 2006 Oct; 314(5796):130-3. PubMed ID: 17023659
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An
    Cascella R; Banchelli M; Abolghasem Ghadami S; Ami D; Gagliani MC; Bigi A; Staderini T; Tampellini D; Cortese K; Cecchi C; Natalello A; Adibi H; Matteini P; Chiti F
    Ann Med; 2023 Dec; 55(1):72-88. PubMed ID: 36495262
    [No Abstract]   [Full Text] [Related]  

  • 20. Early Metastable Assembly during the Stress-Induced Formation of Worm-like Amyloid Fibrils of Nucleic Acid Binding Domains of TDP-43.
    Pillai M; Jha SK
    Biochemistry; 2020 Jan; 59(3):315-328. PubMed ID: 31898895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.