BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 25215859)

  • 1. Shh-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh signalling.
    Kwong L; Bijlsma MF; Roelink H
    Nat Commun; 2014 Sep; 5():4849. PubMed ID: 25215859
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.
    Griffiths SC; Schwab RA; El Omari K; Bishop B; Iverson EJ; Malinauskas T; Dubey R; Qian M; Covey DF; Gilbert RJC; Rohatgi R; Siebold C
    Nat Commun; 2021 Dec; 12(1):7171. PubMed ID: 34887403
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
    Bosanac I; Maun HR; Scales SJ; Wen X; Lingel A; Bazan JF; de Sauvage FJ; Hymowitz SG; Lazarus RA
    Nat Struct Mol Biol; 2009 Jul; 16(7):691-7. PubMed ID: 19561609
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gain-of-function Shh mutants activate Smo cell-autonomously independent of Ptch1/2 function.
    Casillas C; Roelink H
    Mech Dev; 2018 Oct; 153():30-41. PubMed ID: 30144507
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GPR17 is an essential regulator for the temporal adaptation of sonic hedgehog signalling in neural tube development.
    Yatsuzuka A; Hori A; Kadoya M; Matsuo-Takasaki M; Kondo T; Sasai N
    Development; 2019 Sep; 146(17):. PubMed ID: 31444216
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer.
    Taniguchi H; Yamamoto H; Akutsu N; Nosho K; Adachi Y; Imai K; Shinomura Y
    J Pathol; 2007 Oct; 213(2):131-9. PubMed ID: 17724792
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.
    Bishop B; Aricescu AR; Harlos K; O'Callaghan CA; Jones EY; Siebold C
    Nat Struct Mol Biol; 2009 Jul; 16(7):698-703. PubMed ID: 19561611
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.
    Stasiulewicz M; Gray SD; Mastromina I; Silva JC; Björklund M; Seymour PA; Booth D; Thompson C; Green RJ; Hall EA; Serup P; Dale JK
    Development; 2015 Jul; 142(13):2291-303. PubMed ID: 25995356
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ptch2 mediates the Shh response in Ptch1-/- cells.
    Alfaro AC; Roberts B; Kwong L; Bijlsma MF; Roelink H
    Development; 2014 Sep; 141(17):3331-9. PubMed ID: 25085974
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
    Bartl J; Zanini M; Bernardi F; Forget A; Blümel L; Talbot J; Picard D; Qin N; Cancila G; Gao Q; Nath S; Koumba IM; Wolter M; Kuonen F; Langini M; Beez T; Munoz C; Pauck D; Marquardt V; Yu H; Souphron J; Korsch M; Mölders C; Berger D; Göbbels S; Meyer FD; Scheffler B; Rotblat B; Diederichs S; Ramaswamy V; Suzuki H; Oro A; Stühler K; Stefanski A; Fischer U; Leprivier G; Willbold D; Steger G; Buell A; Kool M; Lichter P; Pfister SM; Northcott PA; Taylor MD; Borkhardt A; Reifenberger G; Ayrault O; Remke M
    Nat Commun; 2022 Jul; 13(1):4061. PubMed ID: 35831316
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Single-nucleotide variants in two Hedgehog genes, SHH and HHIP, as genetic cause of combined pituitary hormone deficiency.
    Gorbenko del Blanco D; de Graaff LC; Visser TJ; Hokken-Koelega AC
    Clin Endocrinol (Oxf); 2013 Mar; 78(3):415-23. PubMed ID: 22897141
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The decoupling of Smoothened from Galphai proteins has little effect on Gli3 protein processing and Hedgehog-regulated chick neural tube patterning.
    Low WC; Wang C; Pan Y; Huang XY; Chen JK; Wang B
    Dev Biol; 2008 Sep; 321(1):188-96. PubMed ID: 18590719
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cadherin-7 enhances Sonic Hedgehog signalling by preventing Gli3 repressor formation during neural tube patterning.
    Kawano R; Ohta K; Lupo G
    Open Biol; 2017 Dec; 7(12):. PubMed ID: 29263249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neural tube development depends on notochord-derived sonic hedgehog released into the sclerotome.
    Kahane N; Kalcheim C
    Development; 2020 May; 147(10):. PubMed ID: 32345743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback.
    Ribes V; Briscoe J
    Cold Spring Harb Perspect Biol; 2009 Aug; 1(2):a002014. PubMed ID: 20066087
    [TBL] [Abstract][Full Text] [Related]  

  • 16. miR-326 is downstream of Sonic hedgehog signaling and regulates the expression of Gli2 and smoothened.
    Jiang Z; Cushing L; Ai X; Lü J
    Am J Respir Cell Mol Biol; 2014 Aug; 51(2):273-83. PubMed ID: 24617895
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential promoter usages of PTCH1 and down regulation of HHIP are associated with HNSCC progression.
    Chakraborty B; Basu M; Mukhopadhyay D; Alam N; Ghosh S; Dutta S; Panda CK
    Pathol Res Pract; 2022 Apr; 232():153827. PubMed ID: 35276608
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning.
    Chamberlain CE; Jeong J; Guo C; Allen BL; McMahon AP
    Development; 2008 Mar; 135(6):1097-106. PubMed ID: 18272593
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sonic hedgehog regulates its own receptor on postcrossing commissural axons in a glypican1-dependent manner.
    Wilson NH; Stoeckli ET
    Neuron; 2013 Aug; 79(3):478-91. PubMed ID: 23931997
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hhip regulates zebrafish muscle development by both sequestering Hedgehog and modulating localization of Smoothened.
    Ochi H; Pearson BJ; Chuang PT; Hammerschmidt M; Westerfield M
    Dev Biol; 2006 Sep; 297(1):127-40. PubMed ID: 16765934
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.