These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 25217592)

  • 1. Structural and energetic characterization of the major DNA adduct formed from the food mutagen ochratoxin A in the NarI hotspot sequence: influence of adduct ionization on the conformational preferences and implications for the NER propensity.
    Sharma P; Manderville RA; Wetmore SD
    Nucleic Acids Res; 2014 Oct; 42(18):11831-45. PubMed ID: 25217592
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular Modeling of the Major DNA Adduct Formed from Food Mutagen Ochratoxin A in NarI Two-Base Deletion Duplexes: Impact of Sequence Context and Adduct Ionization on Conformational Preference and Mutagenicity.
    Kathuria P; Sharma P; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2017 Aug; 30(8):1582-1591. PubMed ID: 28719194
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular Dynamics Study of One-Base Deletion Duplexes Containing the Major DNA Adduct Formed by Ochratoxin A: Effects of Sequence Context and Adduct Ionization State on Lesion Site Structure and Mutagenicity.
    Kathuria P; Singh P; Sharma P; Manderville RA; Wetmore SD
    J Phys Chem B; 2019 Aug; 123(32):6980-6989. PubMed ID: 31311268
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular Dynamics Simulations of Mismatched DNA Duplexes Associated with the Major C
    Kathuria P; Sharma P; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2018 Aug; 31(8):712-720. PubMed ID: 29924599
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutagenicity of Ochratoxin A: Role for a Carbon-Linked C8-Deoxyguanosine Adduct?
    Manderville RA; Wetmore SD
    J Agric Food Chem; 2017 Aug; 65(33):7097-7105. PubMed ID: 28830149
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modeling the conformational preference of the carbon-bonded covalent adduct formed upon exposure of 2'-deoxyguanosine to ochratoxin A.
    Sharma P; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2013 May; 26(5):803-16. PubMed ID: 23560542
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Understanding the Mutagenicity of O-Linked and C-Linked Guanine DNA Adducts: A Combined Experimental and Computational Approach.
    Manderville RA; Wetmore SD
    Chem Res Toxicol; 2017 Jan; 30(1):177-188. PubMed ID: 27768845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Influence of the linkage type and functional groups in the carcinogenic moiety on the conformational preferences of damaged DNA: structural and energetic characterization of carbon- and oxygen-linked C(8)-phenolic-guanine adducts.
    Sharma P; Majdi Yazdi M; Merriman A; Manderville RA; Wetmore SD
    Chem Res Toxicol; 2015 Apr; 28(4):782-96. PubMed ID: 25658653
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational Preference and Fluorescence Response of a C-Linked C8-Biphenyl-Guanine Lesion in the NarI Mutational Hotspot: Evidence for Enhanced Syn Adduct Formation.
    Berger FD; Sturla SJ; Kung RW; Montina T; Wetmore SD; Manderville RA
    Chem Res Toxicol; 2018 Jan; 31(1):37-47. PubMed ID: 29186656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context.
    Mao B; Gorin A; Gu Z; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(47):14479-90. PubMed ID: 9398167
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicity.
    Sproviero M; Verwey AM; Rankin KM; Witham AA; Soldatov DV; Manderville RA; Fekry MI; Sturla SJ; Sharma P; Wetmore SD
    Nucleic Acids Res; 2014 Dec; 42(21):13405-21. PubMed ID: 25361967
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA sequence modulates the conformation of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme.
    Wang F; Elmquist CE; Stover JS; Rizzo CJ; Stone MP
    Biochemistry; 2007 Jul; 46(29):8498-516. PubMed ID: 17602664
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solution structure of the aminofluorene [AF]-external conformer of the anti-[AF]-C8-dG adduct opposite dC in a DNA duplex.
    Mao B; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1998 Jan; 37(1):95-106. PubMed ID: 9425029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solution conformation of [AF]dG opposite a -2 deletion site in a DNA duplex: intercalation of the covalently attached aminofluorene ring into the helix with base displacement of the C8-modified syn guanine and adjacent unpaired 3'-adenine into the major groove.
    Mao B; Hingerty BE; Broyde S; Patel DJ
    Biochemistry; 1995 Dec; 34(51):16641-53. PubMed ID: 8527437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA Adduct Positioned at the Nonreiterated G(1) in the NarI Restriction Site.
    Stavros KM; Hawkins EK; Rizzo CJ; Stone MP
    Chem Res Toxicol; 2015 Jul; 28(7):1455-68. PubMed ID: 26083477
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove.
    Cosman M; Hingerty BE; Luneva N; Amin S; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1996 Jul; 35(30):9850-63. PubMed ID: 8703959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies.
    Mu H; Kropachev K; Wang L; Zhang L; Kolbanovskiy A; Kolbanovskiy M; Geacintov NE; Broyde S
    Nucleic Acids Res; 2012 Oct; 40(19):9675-90. PubMed ID: 22904073
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Base-Displaced Intercalated Structure of the N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduct.
    Politica DA; Malik CK; Basu AK; Stone MP
    Chem Res Toxicol; 2015 Dec; 28(12):2253-66. PubMed ID: 26641105
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
    Cosman M; Fiala R; Hingerty BE; Amin S; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1994 Sep; 33(38):11518-27. PubMed ID: 7918365
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of Watson-Crick and Hoogsteen base pairing on the conformational stability of C8-phenoxyl-2'-deoxyguanosine adducts.
    Millen AL; Churchill CD; Manderville RA; Wetmore SD
    J Phys Chem B; 2010 Oct; 114(40):12995-3004. PubMed ID: 20853889
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.