These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

752 related articles for article (PubMed ID: 25217959)

  • 1. An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome.
    Canna SW; de Jesus AA; Gouni S; Brooks SR; Marrero B; Liu Y; DiMattia MA; Zaal KJ; Sanchez GA; Kim H; Chapelle D; Plass N; Huang Y; Villarino AV; Biancotto A; Fleisher TA; Duncan JA; O'Shea JJ; Benseler S; Grom A; Deng Z; Laxer RM; Goldbach-Mansky R
    Nat Genet; 2014 Oct; 46(10):1140-6. PubMed ID: 25217959
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Novel Mutation in the NBD Domain of
    Wang L; Wen W; Deng M; Li Y; Sun G; Zhao X; Tang X; Mao H
    Front Immunol; 2021; 12():674808. PubMed ID: 34248956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.
    Moghaddas F; Zeng P; Zhang Y; Schützle H; Brenner S; Hofmann SR; Berner R; Zhao Y; Lu B; Chen X; Zhang L; Cheng S; Winkler S; Lehmberg K; Canna SW; Czabotar PE; Wicks IP; De Nardo D; Hedrich CM; Zeng H; Masters SL
    J Allergy Clin Immunol; 2018 Dec; 142(6):1956-1967.e6. PubMed ID: 29778503
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NLRC4 gets out of control.
    Khameneh HJ; Mortellaro A
    Nat Genet; 2014 Oct; 46(10):1048-9. PubMed ID: 25257084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.
    Weiss ES; Girard-Guyonvarc'h C; Holzinger D; de Jesus AA; Tariq Z; Picarsic J; Schiffrin EJ; Foell D; Grom AA; Ammann S; Ehl S; Hoshino T; Goldbach-Mansky R; Gabay C; Canna SW
    Blood; 2018 Mar; 131(13):1442-1455. PubMed ID: 29326099
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation.
    Romberg N; Al Moussawi K; Nelson-Williams C; Stiegler AL; Loring E; Choi M; Overton J; Meffre E; Khokha MK; Huttner AJ; West B; Podoltsev NA; Boggon TJ; Kazmierczak BI; Lifton RP
    Nat Genet; 2014 Oct; 46(10):1135-1139. PubMed ID: 25217960
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autoinflammation: NLRC4 mutation causes rare autoinflammatory disease.
    Bernard NJ
    Nat Rev Rheumatol; 2014 Nov; 10(11):635. PubMed ID: 25266450
    [No Abstract]   [Full Text] [Related]  

  • 8. An inherited mutation in NLRC4 causes autoinflammation in human and mice.
    Kitamura A; Sasaki Y; Abe T; Kano H; Yasutomo K
    J Exp Med; 2014 Nov; 211(12):2385-96. PubMed ID: 25385754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rapamycin as an Adjunctive Therapy for NLRC4 Associated Macrophage Activation Syndrome.
    Barsalou J; Blincoe A; Fernandez I; Dal-Soglio D; Marchitto L; Selleri S; Haddad E; Benyoucef A; Touzot F
    Front Immunol; 2018; 9():2162. PubMed ID: 30319625
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Variants in NLRP3 and NLRC4 inflammasome associate with susceptibility and severity of multiple sclerosis.
    Soares JL; Oliveira EM; Pontillo A
    Mult Scler Relat Disord; 2019 Apr; 29():26-34. PubMed ID: 30658261
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NLRC4 gain-of-function variant is identified in a patient with systemic lupus erythematosus.
    Wang Q; Ye X; Zheng W; Jin T; Zhou Y; Hu X; Zhou Q; Yu X
    Clin Immunol; 2023 Oct; 255():109731. PubMed ID: 37567492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Familial Mediterranean fever mutations are hypermorphic mutations that specifically decrease the activation threshold of the Pyrin inflammasome.
    Jamilloux Y; Lefeuvre L; Magnotti F; Martin A; Benezech S; Allatif O; Penel-Page M; Hentgen V; Sève P; Gerfaud-Valentin M; Duquesne A; Desjonquères M; Laurent A; Rémy-Piccolo V; Cimaz R; Cantarini L; Bourdonnay E; Walzer T; Py BF; Belot A; Henry T
    Rheumatology (Oxford); 2018 Jan; 57(1):100-111. PubMed ID: 29040788
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel NLRC4 Mutation Causes a Syndrome of Perinatal Autoinflammation With Hemophagocytic Lymphohistiocytosis, Hepatosplenomegaly, Fetal Thrombotic Vasculopathy, and Congenital Anemia and Ascites.
    Liang J; Alfano DN; Squires JE; Riley MM; Parks WT; Kofler J; El-Gharbawy A; Madan-Kheterpal S; Acquaro R; Picarsic J
    Pediatr Dev Pathol; 2017; 20(6):498-505. PubMed ID: 28403691
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel de novo NLRC4 mutation reinforces the likely pathogenicity of specific LRR domain mutation.
    Chear CT; Nallusamy R; Canna SW; Chan KC; Baharin MF; Hishamshah M; Ghani H; Ripen AM; Mohamad SB
    Clin Immunol; 2020 Feb; 211():108328. PubMed ID: 31870725
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of NLRC4 is critical for inflammasome activation.
    Qu Y; Misaghi S; Izrael-Tomasevic A; Newton K; Gilmour LL; Lamkanfi M; Louie S; Kayagaki N; Liu J; Kömüves L; Cupp JE; Arnott D; Monack D; Dixit VM
    Nature; 2012 Oct; 490(7421):539-42. PubMed ID: 22885697
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The autoinflammation-associated NLRC4
    Eeckhout E; Asaoka T; Van Gorp H; Demon D; Girard-Guyonvarc'h C; Andries V; Vereecke L; Gabay C; Lamkanfi M; van Loo G; Wullaert A
    Front Immunol; 2023; 14():1272639. PubMed ID: 38090573
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition.
    Canna SW; Girard C; Malle L; de Jesus A; Romberg N; Kelsen J; Surrey LF; Russo P; Sleight A; Schiffrin E; Gabay C; Goldbach-Mansky R; Behrens EM
    J Allergy Clin Immunol; 2017 May; 139(5):1698-1701. PubMed ID: 27876626
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus.
    Steiner A; Reygaerts T; Pontillo A; Ceccherini I; Moecking J; Moghaddas F; Davidson S; Caroli F; Grossi A; Castro FFM; Kalil J; Gohr FN; Schmidt FI; Bartok E; Zillinger T; Hartmann G; Geyer M; Gattorno M; Mendonça LO; Masters SL
    J Clin Immunol; 2022 Feb; 42(2):325-335. PubMed ID: 34783940
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4.
    Raghawan AK; Ramaswamy R; Radha V; Swarup G
    Proc Natl Acad Sci U S A; 2019 Oct; 116(43):21694-21703. PubMed ID: 31597739
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation.
    Guan C; Huang X; Yue J; Xiang H; Shaheen S; Jiang Z; Tao Y; Tu J; Liu Z; Yao Y; Yang W; Hou Z; Liu J; Yang XD; Zou Q; Su B; Liu Z; Ni J; Cheng J; Wu X
    Theranostics; 2021; 11(8):3981-3995. PubMed ID: 33664876
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 38.