272 related articles for article (PubMed ID: 25218134)
1. The spermidine analogue GC7 (N1-guanyl-1,7-diamineoheptane) induces autophagy through a mechanism not involving the hypusination of eIF5A.
Oliverio S; Corazzari M; Sestito C; Piredda L; Ippolito G; Piacentini M
Amino Acids; 2014 Dec; 46(12):2767-76. PubMed ID: 25218134
[TBL] [Abstract][Full Text] [Related]
2. Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
Schultz CR; Geerts D; Mooney M; El-Khawaja R; Koster J; Bachmann AS
Biochem J; 2018 Jan; 475(2):531-545. PubMed ID: 29295892
[TBL] [Abstract][Full Text] [Related]
3. Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport.
Hyvönen MT; Khomutov M; Petit M; Weisell J; Kochetkov SN; Alhonen L; Vepsäläinen J; Khomutov AR; Keinänen TA
ACS Chem Biol; 2015 Jun; 10(6):1417-24. PubMed ID: 25689365
[TBL] [Abstract][Full Text] [Related]
4. Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation.
Coni S; Serrao SM; Yurtsever ZN; Di Magno L; Bordone R; Bertani C; Licursi V; Ianniello Z; Infante P; Moretti M; Petroni M; Guerrieri F; Fatica A; Macone A; De Smaele E; Di Marcotullio L; Giannini G; Maroder M; Agostinelli E; Canettieri G
Cell Death Dis; 2020 Dec; 11(12):1045. PubMed ID: 33303756
[TBL] [Abstract][Full Text] [Related]
5. Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification.
Wolff EC; Kang KR; Kim YS; Park MH
Amino Acids; 2007 Aug; 33(2):341-50. PubMed ID: 17476569
[TBL] [Abstract][Full Text] [Related]
6. Independent roles of eIF5A and polyamines in cell proliferation.
Nishimura K; Murozumi K; Shirahata A; Park MH; Kashiwagi K; Igarashi K
Biochem J; 2005 Feb; 385(Pt 3):779-85. PubMed ID: 15377278
[TBL] [Abstract][Full Text] [Related]
7. eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction.
Liang Y; Piao C; Beuschel CB; Toppe D; Kollipara L; Bogdanow B; Maglione M; Lützkendorf J; See JCK; Huang S; Conrad TOF; Kintscher U; Madeo F; Liu F; Sickmann A; Sigrist SJ
Cell Rep; 2021 Apr; 35(2):108941. PubMed ID: 33852845
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of Eukaryotic Translation Initiation Factor 5A (eIF5A) Hypusination Suppress p53 Translation and Alters the Association of eIF5A to the Ribosomes.
Martella M; Catalanotto C; Talora C; La Teana A; Londei P; Benelli D
Int J Mol Sci; 2020 Jun; 21(13):. PubMed ID: 32605139
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy.
Bourourou M; Gouix E; Melis N; Friard J; Heurteaux C; Tauc M; Blondeau N
J Cereb Blood Flow Metab; 2021 May; 41(5):1080-1090. PubMed ID: 32615885
[TBL] [Abstract][Full Text] [Related]
10. Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.
Nakanishi S; Cleveland JL
Amino Acids; 2016 Oct; 48(10):2353-62. PubMed ID: 27357307
[TBL] [Abstract][Full Text] [Related]
11. Higher activity of recombinant bovine deoxyhypusine synthase vs. human deoxyhypusine synthase.
Huang JK; Tsai S; Huang GH; Gowda PG; Walzer AM; Wen L
Protein Expr Purif; 2004 May; 35(1):32-8. PubMed ID: 15039063
[TBL] [Abstract][Full Text] [Related]
12. Human deoxyhypusine synthase: interrelationship between binding of NAD and substrates.
Lee CH; Park MH
Biochem J; 2000 Dec; 352 Pt 3(Pt 3):851-7. PubMed ID: 11104695
[TBL] [Abstract][Full Text] [Related]
13. The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).
Park MH
J Biochem; 2006 Feb; 139(2):161-9. PubMed ID: 16452303
[TBL] [Abstract][Full Text] [Related]
14. Insights Into the Binding Mechanism of GC7 to Deoxyhypusine Synthase in
D'Agostino M; Motta S; Romagnoli A; Orlando P; Tiano L; La Teana A; Di Marino D
Front Chem; 2020; 8():609942. PubMed ID: 33392152
[TBL] [Abstract][Full Text] [Related]
15. Production of active recombinant eIF5A: reconstitution in E.coli of eukaryotic hypusine modification of eIF5A by its coexpression with modifying enzymes.
Park JH; Dias CA; Lee SB; Valentini SR; Sokabe M; Fraser CS; Park MH
Protein Eng Des Sel; 2011 Mar; 24(3):301-9. PubMed ID: 21131325
[TBL] [Abstract][Full Text] [Related]
16. Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation.
Luchessi AD; Cambiaghi TD; Hirabara SM; Lambertucci RH; Silveira LR; Baptista IL; Moriscot AS; Costa-Neto CM; Curi R
J Cell Physiol; 2009 Mar; 218(3):480-9. PubMed ID: 19006180
[TBL] [Abstract][Full Text] [Related]
17. Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase.
Wątor E; Wilk P; Grudnik P
Biomolecules; 2020 Mar; 10(4):. PubMed ID: 32235505
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes.
Robbins RD; Tersey SA; Ogihara T; Gupta D; Farb TB; Ficorilli J; Bokvist K; Maier B; Mirmira RG
J Biol Chem; 2010 Dec; 285(51):39943-52. PubMed ID: 20956533
[TBL] [Abstract][Full Text] [Related]
19. Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis.
Lee Y; Kim HK; Park HE; Park MH; Joe YA
Mol Cell Biochem; 2002 Aug; 237(1-2):69-76. PubMed ID: 12236588
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of eukaryotic translation initiation factor 5A (eIF5A) hypusination impairs melanoma growth.
Jasiulionis MG; Luchessi AD; Moreira AG; Souza PP; Suenaga AP; Correa M; Costa CA; Curi R; Costa-Neto CM
Cell Biochem Funct; 2007; 25(1):109-14. PubMed ID: 16850525
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
