BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

388 related articles for article (PubMed ID: 25218637)

  • 1. RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.
    Pefani DE; Latusek R; Pires I; Grawenda AM; Yee KS; Hamilton G; van der Weyden L; Esashi F; Hammond EM; O'Neill E
    Nat Cell Biol; 2014 Oct; 16(10):962-71, 1-8. PubMed ID: 25218637
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks.
    Pefani DE; O'Neill E
    Cell Cycle; 2015; 14(11):1624-30. PubMed ID: 25927241
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25847274
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25773776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery.
    Ammazzalorso F; Pirzio LM; Bignami M; Franchitto A; Pichierri P
    EMBO J; 2010 Sep; 29(18):3156-69. PubMed ID: 20802463
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATR and H2AX cooperate in maintaining genome stability under replication stress.
    Chanoux RA; Yin B; Urtishak KA; Asare A; Bassing CH; Brown EJ
    J Biol Chem; 2009 Feb; 284(9):5994-6003. PubMed ID: 19049966
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.
    Kolinjivadi AM; Sannino V; De Antoni A; Zadorozhny K; Kilkenny M; Técher H; Baldi G; Shen R; Ciccia A; Pellegrini L; Krejci L; Costanzo V
    Mol Cell; 2017 Sep; 67(5):867-881.e7. PubMed ID: 28757209
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.
    Sirbu BM; Lachmayer SJ; Wülfing V; Marten LM; Clarkson KE; Lee LW; Gheorghiu L; Zou L; Powell SN; Dahm-Daphi J; Willers H
    PLoS One; 2011; 6(8):e23053. PubMed ID: 21857991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.
    Murphy AK; Fitzgerald M; Ro T; Kim JH; Rabinowitsch AI; Chowdhury D; Schildkraut CL; Borowiec JA
    J Cell Biol; 2014 Aug; 206(4):493-507. PubMed ID: 25113031
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BRCA2 coordinates the activities of cell-cycle kinases to promote genome stability.
    Yata K; Bleuyard JY; Nakato R; Ralf C; Katou Y; Schwab RA; Niedzwiedz W; Shirahige K; Esashi F
    Cell Rep; 2014 Jun; 7(5):1547-1559. PubMed ID: 24835992
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
    Dungrawala H; Bhat KP; Le Meur R; Chazin WJ; Ding X; Sharan SK; Wessel SR; Sathe AA; Zhao R; Cortez D
    Mol Cell; 2017 Aug; 67(3):374-386.e5. PubMed ID: 28735897
    [TBL] [Abstract][Full Text] [Related]  

  • 12. H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours.
    Dibitetto D; Liptay M; Vivalda F; Dogan H; Gogola E; González Fernández M; Duarte A; Schmid JA; Decollogny M; Francica P; Przetocka S; Durant ST; Forment JV; Klebic I; Siffert M; de Bruijn R; Kousholt AN; Marti NA; Dettwiler M; Sørensen CS; Tille JC; Undurraga M; Labidi-Galy I; Lopes M; Sartori AA; Jonkers J; Rottenberg S
    Nat Commun; 2024 May; 15(1):4430. PubMed ID: 38789420
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair.
    Peterson SE; Li Y; Chait BT; Gottesman ME; Baer R; Gautier J
    J Cell Biol; 2011 Sep; 194(5):705-20. PubMed ID: 21893598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The BRCA2 and CDKN1A-interacting protein (BCCIP) stabilizes stalled replication forks and prevents degradation of nascent DNA.
    Singh B; Roy Chowdhury S; Mansuri MS; Pillai SJ; Mehrotra S
    FEBS Lett; 2022 Aug; 596(16):2041-2055. PubMed ID: 35592921
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response.
    Saxena S; Dixit S; Somyajit K; Nagaraju G
    Cell Rep; 2019 Oct; 29(3):551-559.e4. PubMed ID: 31618626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Brca2, Rad51 and Mre11: performing balancing acts on replication forks.
    Costanzo V
    DNA Repair (Amst); 2011 Oct; 10(10):1060-5. PubMed ID: 21900052
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability.
    Hjorth-Jensen K; Maya-Mendoza A; Dalgaard N; Sigurðsson JO; Bartek J; Iglesias-Gato D; Olsen JV; Flores-Morales A
    Nucleic Acids Res; 2018 Oct; 46(18):9484-9495. PubMed ID: 30124983
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.
    Zhao W; Wiese C; Kwon Y; Hromas R; Sung P
    Annu Rev Biochem; 2019 Jun; 88():221-245. PubMed ID: 30917004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases.
    Cousineau I; Belmaaza A
    Mol Genet Genomics; 2011 Apr; 285(4):325-40. PubMed ID: 21409565
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping.
    Badie S; Escandell JM; Bouwman P; Carlos AR; Thanasoula M; Gallardo MM; Suram A; Jaco I; Benitez J; Herbig U; Blasco MA; Jonkers J; Tarsounas M
    Nat Struct Mol Biol; 2010 Dec; 17(12):1461-9. PubMed ID: 21076401
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.