293 related articles for article (PubMed ID: 25219851)
1. Discovery and characterization of small molecules that target the GTPase Ral.
Yan C; Liu D; Li L; Wempe MF; Guin S; Khanna M; Meier J; Hoffman B; Owens C; Wysoczynski CL; Nitz MD; Knabe WE; Ahmed M; Brautigan DL; Paschal BM; Schwartz MA; Jones DN; Ross D; Meroueh SO; Theodorescu D
Nature; 2014 Nov; 515(7527):443-7. PubMed ID: 25219851
[TBL] [Abstract][Full Text] [Related]
2. Drugging the Ral GTPase.
Yan C; Jones DN; Theodorescu D
Small GTPases; 2015; 6(3):157-9. PubMed ID: 26280620
[TBL] [Abstract][Full Text] [Related]
3. RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer.
Yan C; Theodorescu D
Pharmacol Rev; 2018 Jan; 70(1):1-11. PubMed ID: 29196555
[TBL] [Abstract][Full Text] [Related]
4. Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.
Hurd CA; Brear P; Revell J; Ross S; Mott HR; Owen D
J Biol Chem; 2021; 296():100101. PubMed ID: 33214225
[TBL] [Abstract][Full Text] [Related]
5. The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector.
Neel NF; Rossman KL; Martin TD; Hayes TK; Yeh JJ; Der CJ
Mol Cell Biol; 2012 Apr; 32(8):1374-86. PubMed ID: 22331470
[TBL] [Abstract][Full Text] [Related]
6. Ral GTPases in tumorigenesis: emerging from the shadows.
Kashatus DF
Exp Cell Res; 2013 Sep; 319(15):2337-42. PubMed ID: 23830877
[TBL] [Abstract][Full Text] [Related]
7. Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation.
Kidd AR; Snider JL; Martin TD; Graboski SF; Der CJ; Cox AD
Int J Radiat Oncol Biol Phys; 2010 Sep; 78(1):205-12. PubMed ID: 20619549
[TBL] [Abstract][Full Text] [Related]
8. Re: Discovery and Characterization of Small Molecules that Target the GTPase Ral.
Atala A
J Urol; 2015 Jul; 194(1):259. PubMed ID: 26088252
[No Abstract] [Full Text] [Related]
9. Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA.
Lim KH; Brady DC; Kashatus DF; Ancrile BB; Der CJ; Cox AD; Counter CM
Mol Cell Biol; 2010 Jan; 30(2):508-23. PubMed ID: 19901077
[TBL] [Abstract][Full Text] [Related]
10. The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
Thies KA; Cole MW; Schafer RE; Spehar JM; Richardson DS; Steck SA; Das M; Lian AW; Ray A; Shakya R; Knoblaugh SE; Timmers CD; Ostrowski MC; Chakravarti A; Sizemore GM; Sizemore ST
Breast Cancer Res; 2021 Jun; 23(1):65. PubMed ID: 34118960
[TBL] [Abstract][Full Text] [Related]
11. Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis.
Issaq SH; Lim KH; Counter CM
Mol Cancer Res; 2010 Feb; 8(2):223-31. PubMed ID: 20145037
[TBL] [Abstract][Full Text] [Related]
12. The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction.
Fenwick RB; Campbell LJ; Rajasekar K; Prasannan S; Nietlispach D; Camonis J; Owen D; Mott HR
Structure; 2010 Aug; 18(8):985-95. PubMed ID: 20696399
[TBL] [Abstract][Full Text] [Related]
13. RalBP1 is necessary for metastasis of human cancer cell lines.
Wu Z; Owens C; Chandra N; Popovic K; Conaway M; Theodorescu D
Neoplasia; 2010 Dec; 12(12):1003-12. PubMed ID: 21170262
[TBL] [Abstract][Full Text] [Related]
14. Small molecules inhibit the RAS-like small GTPases RALA and RALB.
Cancer Discov; 2014 Nov; 4(11):1251. PubMed ID: 25367937
[TBL] [Abstract][Full Text] [Related]
15. The RAL signaling network: Cancer and beyond.
Apken LH; Oeckinghaus A
Int Rev Cell Mol Biol; 2021; 361():21-105. PubMed ID: 34074494
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of Ral GTPases Using a Stapled Peptide Approach.
Thomas JC; Cooper JM; Clayton NS; Wang C; White MA; Abell C; Owen D; Mott HR
J Biol Chem; 2016 Aug; 291(35):18310-25. PubMed ID: 27334922
[TBL] [Abstract][Full Text] [Related]
17. Therapy: GTPase Ral-a new tumour target.
Thoma C
Nat Rev Urol; 2014 Dec; 11(12):658. PubMed ID: 25266572
[No Abstract] [Full Text] [Related]
18. Dual effects of Ral-activated pathways on p27 localization and TGF-β signaling.
Tazat K; Harsat M; Goldshmid-Shagal A; Ehrlich M; Henis YI
Mol Biol Cell; 2013 Jun; 24(11):1812-24. PubMed ID: 23576547
[TBL] [Abstract][Full Text] [Related]
19. Contributions of KRAS and RAL in non-small-cell lung cancer growth and progression.
Guin S; Ru Y; Wynes MW; Mishra R; Lu X; Owens C; Barn AE; Vasu VT; Hirsch FR; Kern JA; Theodorescu D
J Thorac Oncol; 2013 Dec; 8(12):1492-501. PubMed ID: 24389431
[TBL] [Abstract][Full Text] [Related]
20. The structure of the RLIP76 RhoGAP-Ral binding domain dyad: fixed position of the domains leads to dual engagement of small G proteins at the membrane.
Rajasekar KV; Campbell LJ; Nietlispach D; Owen D; Mott HR
Structure; 2013 Dec; 21(12):2131-42. PubMed ID: 24207123
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]