140 related articles for article (PubMed ID: 25219965)
1. Targeted suppression of EVI1 oncogene expression by sequence-specific pyrrole-imidazole polyamide.
Syed J; Pandian GN; Sato S; Taniguchi J; Chandran A; Hashiya K; Bando T; Sugiyama H
Chem Biol; 2014 Oct; 21(10):1370-1380. PubMed ID: 25219965
[TBL] [Abstract][Full Text] [Related]
2. Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.
Zhang Y; Sicot G; Cui X; Vogel M; Wuertzer CA; Lezon-Geyda K; Wheeler J; Harki DA; Muzikar KA; Stolper DA; Dervan PB; Perkins AS
Biochemistry; 2011 Dec; 50(48):10431-41. PubMed ID: 22039883
[TBL] [Abstract][Full Text] [Related]
3. Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.
Maicas M; Vázquez I; Vicente C; García-Sánchez MA; Marcotegui N; Urquiza L; Calasanz MJ; Odero MD
Oncogene; 2013 Apr; 32(16):2069-78. PubMed ID: 22689058
[TBL] [Abstract][Full Text] [Related]
4. Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides.
Dickinson LA; Trauger JW; Baird EE; Ghazal P; Dervan PB; Gottesfeld JM
Biochemistry; 1999 Aug; 38(33):10801-7. PubMed ID: 10451376
[TBL] [Abstract][Full Text] [Related]
5. A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function.
Ueno T; Fukuda N; Tsunemi A; Yao EH; Matsuda H; Tahira K; Matsumoto T; Matsumoto K; Matsumoto Y; Nagase H; Sugiyama H; Sawamura T
J Hypertens; 2009 Mar; 27(3):508-16. PubMed ID: 19330905
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and anti-cancer activity of pyrrole-imidazole polyamides through target-downregulation of c-kit gene expression.
Zhang M; Liang J; Jiang SK; Xu L; Wu YL; Awadasseid A; Zhao XY; Xiong XQ; Sugiyama H; Zhang W
Eur J Med Chem; 2020 Dec; 207():112704. PubMed ID: 32866755
[TBL] [Abstract][Full Text] [Related]
7. Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome.
Lin J; Hiraoka K; Watanabe T; Kuo T; Shinozaki Y; Takatori A; Koshikawa N; Chandran A; Otsuki J; Sugiyama H; Horton P; Nagase H
PLoS One; 2016; 11(10):e0165581. PubMed ID: 27798693
[TBL] [Abstract][Full Text] [Related]
8. Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation.
Mishra R; Watanabe T; Kimura MT; Koshikawa N; Ikeda M; Uekusa S; Kawashima H; Wang X; Igarashi J; Choudhury D; Grandori C; Kemp CJ; Ohira M; Verma NK; Kobayashi Y; Takeuchi J; Koshinaga T; Nemoto N; Fukuda N; Soma M; Kusafuka T; Fujiwara K; Nagase H
Cancer Sci; 2015 Apr; 106(4):421-9. PubMed ID: 25611295
[TBL] [Abstract][Full Text] [Related]
9. Functional features of EVI1 and EVI1Δ324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity.
Sayadi A; Jeyakani J; Seet SH; Wei CL; Bourque G; Bard FA; Jenkins NA; Copeland NG; Bard-Chapeau EA
Oncogene; 2016 May; 35(18):2311-21. PubMed ID: 26234679
[TBL] [Abstract][Full Text] [Related]
10. Targeted suppression of metastasis regulatory transcription factor SOX2 in various cancer cell lines using a sequence-specific designer pyrrole-imidazole polyamide.
Malinee M; Kumar A; Hidaka T; Horie M; Hasegawa K; Pandian GN; Sugiyama H
Bioorg Med Chem; 2020 Feb; 28(3):115248. PubMed ID: 31879179
[TBL] [Abstract][Full Text] [Related]
11. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
[TBL] [Abstract][Full Text] [Related]
12. Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.
Hargrove AE; Martinez TF; Hare AA; Kurmis AA; Phillips JW; Sud S; Pienta KJ; Dervan PB
PLoS One; 2015; 10(11):e0143161. PubMed ID: 26571387
[TBL] [Abstract][Full Text] [Related]
13. Suppression of GPR56 expression by pyrrole-imidazole polyamide represents a novel therapeutic drug for AML with high EVI1 expression.
Saha HR; Kaneda-Nakashima K; Shimosaki S; Suekane A; Sarkar B; Saito Y; Ogoh H; Nakahata S; Inoue K; Watanabe T; Nagase H; Morishita K
Sci Rep; 2018 Sep; 8(1):13741. PubMed ID: 30214063
[TBL] [Abstract][Full Text] [Related]
14. Development of pyrrole-imidazole polyamide for specific regulation of human aurora kinase-A and -B gene expression.
Takahashi T; Asami Y; Kitamura E; Suzuki T; Wang X; Igarashi J; Morohashi A; Shinojima Y; Kanou H; Saito K; Takasu T; Nagase H; Harada Y; Kuroda K; Watanabe T; Kumamoto S; Aoyama T; Matsumoto Y; Bando T; Sugiyama H; Yoshida-Noro C; Fukuda N; Hayashi N
Chem Biol; 2008 Aug; 15(8):829-41. PubMed ID: 18721754
[TBL] [Abstract][Full Text] [Related]
15. Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model.
Igarashi J; Fukuda N; Inoue T; Nakai S; Saito K; Fujiwara K; Matsuda H; Ueno T; Matsumoto Y; Watanabe T; Nagase H; Bando T; Sugiyama H; Itoh T; Soma M
PLoS One; 2015; 10(5):e0125295. PubMed ID: 25938472
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides.
Bando T; Sugiyama H
Acc Chem Res; 2006 Dec; 39(12):935-44. PubMed ID: 17176032
[TBL] [Abstract][Full Text] [Related]
17. Sequence specific suppression of androgen receptor-DNA binding in vivo by a Py-Im polyamide.
Kurmis AA; Dervan PB
Nucleic Acids Res; 2019 May; 47(8):3828-3835. PubMed ID: 30838415
[TBL] [Abstract][Full Text] [Related]
18. Regulation of gene expression by small molecules.
Gottesfeld JM; Neely L; Trauger JW; Baird EE; Dervan PB
Nature; 1997 May; 387(6629):202-5. PubMed ID: 9144294
[TBL] [Abstract][Full Text] [Related]
19. Discovery of Pyrrole-imidazole Polyamides as PD-L1 Expression Inhibitors and Their Anticancer Activity via Immune and Nonimmune Pathways.
Wang M; Ma X; Zhou K; Mao H; Liu J; Xiong X; Zhao X; Narva S; Tanaka Y; Wu Y; Guo C; Sugiyama H; Zhang W
J Med Chem; 2021 May; 64(9):6021-6036. PubMed ID: 33949196
[TBL] [Abstract][Full Text] [Related]
20. EVI1 oncogene promotes KRAS pathway through suppression of microRNA-96 in pancreatic carcinogenesis.
Tanaka M; Suzuki HI; Shibahara J; Kunita A; Isagawa T; Yoshimi A; Kurokawa M; Miyazono K; Aburatani H; Ishikawa S; Fukayama M
Oncogene; 2014 May; 33(19):2454-63. PubMed ID: 23752186
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]