BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 25224041)

  • 1. The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair.
    Li M; Lin YF; Palchik GA; Matsunaga S; Wang D; Chen BP
    Free Radic Biol Med; 2014 Nov; 76():278-85. PubMed ID: 25224041
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA-Dependent Protein Kinase Catalytic Subunit: The Sensor for DNA Double-Strand Breaks Structurally and Functionally Related to Ataxia Telangiectasia Mutated.
    Matsumoto Y; Asa ADDC; Modak C; Shimada M
    Genes (Basel); 2021 Jul; 12(8):. PubMed ID: 34440313
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA-PKcs and ATM co-regulate DNA double-strand break repair.
    Shrivastav M; Miller CA; De Haro LP; Durant ST; Chen BP; Chen DJ; Nickoloff JA
    DNA Repair (Amst); 2009 Aug; 8(8):920-9. PubMed ID: 19535303
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.
    Zhou Y; Lee JH; Jiang W; Crowe JL; Zha S; Paull TT
    Mol Cell; 2017 Jan; 65(1):91-104. PubMed ID: 27939942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA-PKcs in human cells.
    Xing M; Oksenych V
    FEBS Open Bio; 2019 Jul; 9(7):1315-1326. PubMed ID: 31141305
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APE1 promotes non-homologous end joining by initiating DNA double-strand break formation and decreasing ubiquitination of artemis following oxidative genotoxic stress.
    Zhang Q; Yang L; Gao H; Kuang X; Xiao H; Yang C; Cheng Y; Zhang L; Guo X; Zhong Y; Li M
    J Transl Med; 2023 Mar; 21(1):183. PubMed ID: 36894994
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence.
    Liu Y; Efimova EV; Ramamurthy A; Kron SJ
    J Cell Sci; 2019 Jul; 132(13):. PubMed ID: 31189537
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in the selenium-induced senescence response.
    Rocourt CR; Wu M; Chen BP; Cheng WH
    J Nutr Biochem; 2013 May; 24(5):781-7. PubMed ID: 22841545
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.
    Chen BP; Uematsu N; Kobayashi J; Lerenthal Y; Krempler A; Yajima H; Löbrich M; Shiloh Y; Chen DJ
    J Biol Chem; 2007 Mar; 282(9):6582-7. PubMed ID: 17189255
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks.
    Dong J; Zhang T; Ren Y; Wang Z; Ling CC; He F; Li GC; Wang C; Wen B
    Oncotarget; 2017 Apr; 8(14):22662-22673. PubMed ID: 28186989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of human polλ by ATM-mediated phosphorylation during non-homologous end joining.
    Sastre-Moreno G; Pryor JM; Moreno-Oñate M; Herrero-Ruiz AM; Cortés-Ledesma F; Blanco L; Ramsden DA; Ruiz JF
    DNA Repair (Amst); 2017 Mar; 51():31-45. PubMed ID: 28109743
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress.
    Yajima H; Lee KJ; Chen BP
    Mol Cell Biol; 2006 Oct; 26(20):7520-8. PubMed ID: 16908529
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.
    Lee BS; Gapud EJ; Zhang S; Dorsett Y; Bredemeyer A; George R; Callen E; Daniel JA; Osipovich O; Oltz EM; Bassing CH; Nussenzweig A; Lees-Miller S; Hammel M; Chen BP; Sleckman BP
    Mol Cell Biol; 2013 Sep; 33(18):3568-79. PubMed ID: 23836881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.
    Yajima H; Lee KJ; Zhang S; Kobayashi J; Chen BP
    J Mol Biol; 2009 Jan; 385(3):800-10. PubMed ID: 19071136
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alternative end-joining originates stable chromosome aberrations induced by etoposide during targeted inhibition of DNA-PKcs in ATM-deficient tumor cells.
    de Campos Nebel M; Palmitelli M; Pérez Maturo J; González-Cid M
    Chromosome Res; 2022 Dec; 30(4):459-476. PubMed ID: 35604590
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.
    Toulany M; Lee KJ; Fattah KR; Lin YF; Fehrenbacher B; Schaller M; Chen BP; Chen DJ; Rodemann HP
    Mol Cancer Res; 2012 Jul; 10(7):945-57. PubMed ID: 22596249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity.
    Cui F; Fan R; Chen Q; He Y; Song M; Shang Z; Zhang S; Zhu W; Cao J; Guan H; Zhou PK
    Mol Cell Biochem; 2015 Aug; 406(1-2):43-51. PubMed ID: 26049366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.
    Yu Y; Mahaney BL; Yano K; Ye R; Fang S; Douglas P; Chen DJ; Lees-Miller SP
    DNA Repair (Amst); 2008 Oct; 7(10):1680-92. PubMed ID: 18644470
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression.
    An J; Huang YC; Xu QZ; Zhou LJ; Shang ZF; Huang B; Wang Y; Liu XD; Wu DC; Zhou PK
    BMC Mol Biol; 2010 Mar; 11():18. PubMed ID: 20205745
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining.
    Lu H; Zhang Q; Laverty DJ; Puncheon AC; Augustine MM; Williams GJ; Nagel ZD; Chen BPC; Davis AJ
    Nucleic Acids Res; 2023 Jul; 51(13):6770-6783. PubMed ID: 37309889
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.