257 related articles for article (PubMed ID: 25225870)
1. A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies.
Peterson KR; Costa FC; Fedosyuk H; Neades RY; Chazelle AM; Zelenchuk L; Fonteles AH; Dalal P; Roy A; Chaguturu R; Li B; Pace BS
PLoS One; 2014; 9(9):e107006. PubMed ID: 25225870
[TBL] [Abstract][Full Text] [Related]
2. {gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice.
Blau CA; Barbas CF; Bomhoff AL; Neades R; Yan J; Navas PA; Peterson KR
J Biol Chem; 2005 Nov; 280(44):36642-7. PubMed ID: 16131492
[TBL] [Abstract][Full Text] [Related]
3. Novel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic Mice.
Boosalis MS; Sangerman JI; White GL; Wolf RF; Shen L; Dai Y; White E; Makala LH; Li B; Pace BS; Nouraie M; Faller DV; Perrine SP
PLoS One; 2015; 10(12):e0144660. PubMed ID: 26713848
[TBL] [Abstract][Full Text] [Related]
4. Cilostazol-mediated reversion of γ-globin silencing is associated with a high level of HbF production: A potential therapeutic candidate for β-globin disorders.
Ali H; Khan F; Musharraf SG
Biomed Pharmacother; 2021 Oct; 142():112058. PubMed ID: 34426256
[TBL] [Abstract][Full Text] [Related]
5. Tenofovir disoproxil fumarate induces fetal hemoglobin production in K562 cells and β-YAC transgenic mice: A therapeutic approach for γ-globin induction.
Khan F; Ali H; Musharraf SG
Exp Cell Res; 2020 Sep; 394(2):112168. PubMed ID: 32653411
[TBL] [Abstract][Full Text] [Related]
6. Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells.
Li H; Xie W; Gore ER; Montoute MN; Bee WT; Zappacosta F; Zeng X; Wu Z; Kallal L; Ames RS; Pope AJ; Benowitz A; Erickson-Miller CL
J Biomol Screen; 2013 Dec; 18(10):1212-22. PubMed ID: 24163393
[TBL] [Abstract][Full Text] [Related]
7. Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.
Breveglieri G; Salvatori F; Finotti A; Cosenza LC; Zuccato C; Bianchi N; Breda L; Rivella S; Bresciani A; Bisbocci M; Borgatti M; Gambari R
Anal Bioanal Chem; 2019 Nov; 411(29):7669-7680. PubMed ID: 31273412
[TBL] [Abstract][Full Text] [Related]
8. Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line.
Zein S; Li W; Ramakrishnan V; Lou TF; Sivanand S; Mackie A; Pace B
Exp Biol Med (Maywood); 2010 Nov; 235(11):1385-94. PubMed ID: 20975082
[TBL] [Abstract][Full Text] [Related]
9. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
[TBL] [Abstract][Full Text] [Related]
10. Establishment of cell lines that exhibit correct ontogenic stage-specific gene expression profiles from tissues of yeast artificial chromosome transgenic mice using chemically induced growth signals.
Blau CA; Peterson KR
Methods Mol Biol; 2006; 349():163-73. PubMed ID: 17071982
[TBL] [Abstract][Full Text] [Related]
11. Novel therapeutic candidates, identified by molecular modeling, induce γ-globin gene expression in vivo.
Boosalis MS; Castaneda SA; Trudel M; Mabaera R; White GL; Lowrey CH; Emery DW; Mpollo MS; Shen L; Wargin WA; Bohacek R; Faller DV; Perrine SP
Blood Cells Mol Dis; 2011 Aug; 47(2):107-16. PubMed ID: 21641240
[TBL] [Abstract][Full Text] [Related]
12. siDNMT1 increases γ-globin expression in chemical inducer of dimerization (CID)-dependent mouse βYAC bone marrow cells and in baboon erythroid progenitor cell cultures.
Banzon V; Ibanez V; Vaitkus K; Ruiz MA; Peterson K; DeSimone J; Lavelle D
Exp Hematol; 2011 Jan; 39(1):26-36.e1. PubMed ID: 20974210
[TBL] [Abstract][Full Text] [Related]
13. Compounds of the anthracycline family of antibiotics elevate human gamma-globin expression both in erythroid cultures and in a transgenic mouse model.
Spyrou P; Phylactides M; Lederer CW; Kithreotis L; Kirri A; Christou S; Kkolou E; Kanavakis E; Anagnou NP; Stamatoyannopoulos G; Kleanthous M
Blood Cells Mol Dis; 2010; 44(2):100-6. PubMed ID: 19914848
[TBL] [Abstract][Full Text] [Related]
14. Multiple physical stresses induce γ-globin gene expression and fetal hemoglobin production in erythroid cells.
Schaeffer EK; West RJ; Conine SJ; Lowrey CH
Blood Cells Mol Dis; 2014 Apr; 52(4):214-24. PubMed ID: 24314748
[TBL] [Abstract][Full Text] [Related]
15. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
Wilber A; Hargrove PW; Kim YS; Riberdy JM; Sankaran VG; Papanikolaou E; Georgomanoli M; Anagnou NP; Orkin SH; Nienhuis AW; Persons DA
Blood; 2011 Mar; 117(10):2817-26. PubMed ID: 21156846
[TBL] [Abstract][Full Text] [Related]
16. Phenotypic-screening generates active novel fetal globin-inducers that downregulate Bcl11a in a monkey model.
Makino T; Haruyama M; Katayama K; Terashima H; Tsunemi T; Miyazaki K; Terakawa M; Yamashiro K; Yoshioka R; Maeda H
Biochem Pharmacol; 2020 Jan; 171():113717. PubMed ID: 31751536
[TBL] [Abstract][Full Text] [Related]
17. Original Research: Generation of non-deletional hereditary persistence of fetal hemoglobin β-globin locus yeast artificial chromosome transgenic mouse models: -175 Black HPFH and -195 Brazilian HPFH.
Braghini CA; Costa FC; Fedosyuk H; Neades RY; Novikova LV; Parker MP; Winefield RD; Peterson KR
Exp Biol Med (Maywood); 2016 Apr; 241(7):697-705. PubMed ID: 26946532
[TBL] [Abstract][Full Text] [Related]
18. Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression.
Skarpidi E; Cao H; Heltweg B; White BF; Marhenke RL; Jung M; Stamatoyannopoulos G
Exp Hematol; 2003 Mar; 31(3):197-203. PubMed ID: 12644016
[TBL] [Abstract][Full Text] [Related]
19. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
Ali H; Khan F; Ghulam Musharraf S
Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
[TBL] [Abstract][Full Text] [Related]
20. Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons.
Rivers A; Vaitkus K; Jagadeeswaran R; Ruiz MA; Ibanez V; Ciceri F; Cavalcanti F; Molokie RE; Saunthararajah Y; Engel JD; DeSimone J; Lavelle D
Exp Hematol; 2018 Nov; 67():60-64.e2. PubMed ID: 30125603
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]