BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 25228302)

  • 1. The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes.
    Gerbal-Chaloin S; Dumé AS; Briolotti P; Klieber S; Raulet E; Duret C; Fabre JM; Ramos J; Maurel P; Daujat-Chavanieu M
    Mol Pharmacol; 2014 Dec; 86(6):624-34. PubMed ID: 25228302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.
    Briolotti P; Chaloin L; Balaguer P; Da Silva F; Tománková V; Pascussi JM; Duret C; Fabre JM; Ramos J; Klieber S; Maurel P; Daujat-Chavanieu M; Gerbal-Chaloin S
    Toxicol Sci; 2015 Nov; 148(1):261-75. PubMed ID: 26259606
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activating and Inhibitory Functions of WNT/β-Catenin in the Induction of Cytochromes P450 by Nuclear Receptors in HepaRG Cells.
    Thomas M; Bayha C; Vetter S; Hofmann U; Schwarz M; Zanger UM; Braeuning A
    Mol Pharmacol; 2015 Jun; 87(6):1013-20. PubMed ID: 25824487
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2.
    Xu S; Liu J; Shi J; Wang Z; Ji L
    Sci Rep; 2017 Nov; 7(1):16511. PubMed ID: 29184146
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cooperation of structurally different aryl hydrocarbon receptor agonists and β-catenin in the regulation of CYP1A expression.
    Vaas S; Kreft L; Schwarz M; Braeuning A
    Toxicology; 2014 Nov; 325():31-41. PubMed ID: 25174530
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1.
    Braeuning A; Sanna R; Huelsken J; Schwarz M
    Drug Metab Dispos; 2009 May; 37(5):1138-45. PubMed ID: 19237511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.
    Rasmussen MK; Daujat-Chavanieu M; Gerbal-Chaloin S
    Toxicol Lett; 2017 Aug; 277():1-8. PubMed ID: 28571685
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Coordinate regulation of cytochrome P450 1a1 expression in mouse liver by the aryl hydrocarbon receptor and the beta-catenin pathway.
    Braeuning A; Köhle C; Buchmann A; Schwarz M
    Toxicol Sci; 2011 Jul; 122(1):16-25. PubMed ID: 21498875
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The interplay of the aryl hydrocarbon receptor and β-catenin alters both AhR-dependent transcription and Wnt/β-catenin signaling in liver progenitors.
    Procházková J; Kabátková M; Bryja V; Umannová L; Bernatík O; Kozubík A; Machala M; Vondrácek J
    Toxicol Sci; 2011 Aug; 122(2):349-60. PubMed ID: 21602191
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Coordinate regulation of Cyp2e1 by β-catenin- and hepatocyte nuclear factor 1α-dependent signaling.
    Groll N; Petrikat T; Vetter S; Colnot S; Weiss F; Poetz O; Joos TO; Rothbauer U; Schwarz M; Braeuning A
    Toxicology; 2016 Mar; 350-352():40-8. PubMed ID: 27153753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. β-Catenin Is Required for Endothelial Cyp1b1 Regulation Influencing Metabolic Barrier Function.
    Ziegler N; Awwad K; Fisslthaler B; Reis M; Devraj K; Corada M; Minardi SP; Dejana E; Plate KH; Fleming I; Liebner S
    J Neurosci; 2016 Aug; 36(34):8921-35. PubMed ID: 27559173
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway.
    Xu Y; Chen D; Lin XX; Zhao Q; Guo J; Chen LJ; Zhang W; Xiao J; Lian GH; Peng SF; Guo D; Yang H; Obianom O; Shu Y; Chen Y
    Arch Toxicol; 2019 Jun; 93(6):1679-1695. PubMed ID: 30976847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes.
    Dvorák Z; Vrzal R; Starha P; Klanicová A; Trávnícek Z
    Toxicol In Vitro; 2010 Mar; 24(2):425-9. PubMed ID: 19854261
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The glycogen synthase kinase inhibitor 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione (SB216763) is a partial agonist of the aryl hydrocarbon receptor.
    Braeuning A; Buchmann A
    Drug Metab Dispos; 2009 Aug; 37(8):1576-80. PubMed ID: 19448134
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Microtubules-interfering agents restrict aryl hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of human hepatocytes via c-jun-N-terminal kinase and glucocorticoid receptor.
    Vrzal R; Daujat-Chavanieu M; Pascussi JM; Ulrichova J; Maurel P; Dvorak Z
    Eur J Pharmacol; 2008 Mar; 581(3):244-54. PubMed ID: 18177856
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines.
    Vrzal R; Kubesova K; Pavek P; Dvorak Z
    Toxicol Lett; 2010 Mar; 193(2):183-8. PubMed ID: 20080160
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts.
    Donato MT; Lahoz A; Jiménez N; Pérez G; Serralta A; Mir J; Castell JV; Gómez-Lechón MJ
    Drug Metab Dispos; 2006 Sep; 34(9):1556-62. PubMed ID: 16763015
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The comparative effects of diethyldithiocarbamate-copper complex with established proteasome inhibitors on expression levels of CYP1A2/3A4 and their master regulators, aryl hydrocarbon and pregnane X receptor in primary cultures of human hepatocytes.
    Vrzal R; Dvorak Z
    Fundam Clin Pharmacol; 2016 Dec; 30(6):585-595. PubMed ID: 27414036
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver.
    Giera S; Braeuning A; Köhle C; Bursch W; Metzger U; Buchmann A; Schwarz M
    Toxicol Sci; 2010 May; 115(1):22-33. PubMed ID: 20118494
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.