BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 25228368)

  • 1. Nonclinical pharmacokinetics and activity of etirinotecan pegol (NKTR-102), a long-acting topoisomerase 1 inhibitor, in multiple cancer models.
    Hoch U; Staschen CM; Johnson RK; Eldon MA
    Cancer Chemother Pharmacol; 2014 Dec; 74(6):1125-37. PubMed ID: 25228368
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A multicenter, phase I, dose-escalation study to assess the safety, tolerability, and pharmacokinetics of etirinotecan pegol in patients with refractory solid tumors.
    Jameson GS; Hamm JT; Weiss GJ; Alemany C; Anthony S; Basche M; Ramanathan RK; Borad MJ; Tibes R; Cohn A; Hinshaw I; Jotte R; Rosen LS; Hoch U; Eldon MA; Medve R; Schroeder K; White E; Von Hoff DD
    Clin Cancer Res; 2013 Jan; 19(1):268-78. PubMed ID: 23136196
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Integrated population pharmacokinetics of etirinotecan pegol and its four metabolites in cancer patients with solid tumors.
    Sy SKB; Chia YL; Gordi T; Hoch U; Eldon MA
    Cancer Chemother Pharmacol; 2018 May; 81(5):897-909. PubMed ID: 29564497
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two schedules of etirinotecan pegol (NKTR-102) in patients with previously treated metastatic breast cancer: a randomised phase 2 study.
    Awada A; Garcia AA; Chan S; Jerusalem GH; Coleman RE; Huizing MT; Mehdi A; O'Reilly SM; Hamm JT; Barrett-Lee PJ; Cocquyt V; Sideras K; Young DE; Zhao C; Chia YL; Hoch U; Hannah AL; Perez EA;
    Lancet Oncol; 2013 Nov; 14(12):1216-25. PubMed ID: 24095299
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Etirinotecan pegol for the treatment of breast cancer.
    López-Miranda E; Cortés J
    Expert Opin Pharmacother; 2016; 17(5):727-34. PubMed ID: 26881332
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Randomized multicenter phase II trial comparing two schedules of etirinotecan pegol (NKTR-102) in women with recurrent platinum-resistant/refractory epithelial ovarian cancer.
    Vergote IB; Garcia A; Micha J; Pippitt C; Bendell J; Spitz D; Reed N; Dark G; Fracasso PM; Ibrahim EN; Armenio VA; Duska L; Poole C; Gennigens C; Dirix LY; Leung AC; Zhao C; Soufi-Mahjoubi R; Rustin G
    J Clin Oncol; 2013 Nov; 31(32):4060-6. PubMed ID: 24081946
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Etirinotecan pegol administration is associated with lower incidences of neutropenia compared to irinotecan administration.
    Sy SK; Sweeney TD; Ji C; Hoch U; Eldon MA
    Cancer Chemother Pharmacol; 2017 Jan; 79(1):57-67. PubMed ID: 27904955
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Etirinotecan pegol in women with recurrent platinum-resistant or refractory ovarian cancer.
    Bardhi E; Marchetti C; Scopelliti A; Musacchio L; Tomao F; Schiavi M; Carraro C; Palaia I; Monti M; Muzii L; Benedetti Panici P
    Expert Opin Investig Drugs; 2019 Aug; 28(8):667-673. PubMed ID: 31353973
    [No Abstract]   [Full Text] [Related]  

  • 9. Etirinotecan pegol (NKTR-102) versus treatment of physician's choice in women with advanced breast cancer previously treated with an anthracycline, a taxane, and capecitabine (BEACON): a randomised, open-label, multicentre, phase 3 trial.
    Perez EA; Awada A; O'Shaughnessy J; Rugo HS; Twelves C; Im SA; Gómez-Pardo P; Schwartzberg LS; Diéras V; Yardley DA; Potter DA; Mailliez A; Moreno-Aspitia A; Ahn JS; Zhao C; Hoch U; Tagliaferri M; Hannah AL; Cortes J
    Lancet Oncol; 2015 Nov; 16(15):1556-1568. PubMed ID: 26482278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Etirinotecan pegol: an option for late-stage breast cancer?
    Nielsen DL; Brünner N
    Lancet Oncol; 2013 Nov; 14(12):1149-51. PubMed ID: 24095297
    [No Abstract]   [Full Text] [Related]  

  • 11. Etirinotecan pegol: development of a novel conjugated topoisomerase I inhibitor.
    Alemany C
    Curr Oncol Rep; 2014 Feb; 16(2):367. PubMed ID: 24445499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATTAIN: Phase III study of etirinotecan pegol versus treatment of physician's choice in patients with metastatic breast cancer and brain metastases.
    Tripathy D; Tolaney SM; Seidman AD; Anders CK; Ibrahim N; Rugo HS; Twelves C; Dieras V; Müller V; Tagliaferri M; Hannah AL; Cortés J
    Future Oncol; 2019 Jul; 15(19):2211-2225. PubMed ID: 31074641
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Health-related quality of life in patients with locally recurrent or metastatic breast cancer treated with etirinotecan pegol versus treatment of physician's choice: Results from the randomised phase III BEACON trial.
    Twelves C; Cortés J; O'Shaughnessy J; Awada A; Perez EA; Im SA; Gómez-Pardo P; Schwartzberg LS; Diéras V; Yardley DA; Potter DA; Mailliez A; Moreno-Aspitia A; Ahn JS; Zhao C; Hoch U; Tagliaferri M; Hannah AL; Rugo HS
    Eur J Cancer; 2017 May; 76():205-215. PubMed ID: 28360015
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Etirinotecan Pegol (NKTR-102) in Third-line Treatment of Patients With Metastatic or Recurrent Non-Small-cell Lung Cancer: Results of a Phase II Study.
    Aggarwal C; Cohen RB; Yu E; Hwang WT; Bauml JM; Alley E; Evans TL; Langer CJ
    Clin Lung Cancer; 2018 Mar; 19(2):157-162. PubMed ID: 29129435
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Randomized study of etirinotecan pegol versus irinotecan as second-line treatment for metastatic colorectal cancer.
    Lenz HJ; Philip P; Saunders M; Kolevska T; Mukherjee K; Samuel L; Bondarde S; Dobbs T; Tagliaferri M; Hoch U; Hannah AL; Berkowitz M
    Cancer Chemother Pharmacol; 2017 Dec; 80(6):1161-1169. PubMed ID: 29043412
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PEG-coated irinotecan cationic liposomes improve the therapeutic efficacy of breast cancer in animals.
    Zhang L; Cao DY; Wang J; Xiang B; Dun JN; Fang Y; Xue GQ
    Eur Rev Med Pharmacol Sci; 2013 Dec; 17(24):3347-61. PubMed ID: 24379067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Treatment With Etirinotecan Pegol for Patients With Metastatic Breast Cancer and Brain Metastases: Final Results From the Phase 3 ATTAIN Randomized Clinical Trial.
    Tripathy D; Tolaney SM; Seidman AD; Anders CK; Ibrahim N; Rugo HS; Twelves C; Diéras V; Müller V; Du Y; Currie SL; Hoch U; Tagliaferri M; Hannah AL; Cortés J;
    JAMA Oncol; 2022 Jul; 8(7):1047-1052. PubMed ID: 35552364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer.
    Adkins CE; Nounou MI; Hye T; Mohammad AS; Terrell-Hall T; Mohan NK; Eldon MA; Hoch U; Lockman PR
    BMC Cancer; 2015 Oct; 15():685. PubMed ID: 26463521
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development and pharmacological evaluation of a PEG based nanoparticulate camptothecin analog for oral administration.
    Nekkanti V; Venkateswarlu V; Ansari KA; Pillai R
    Curr Drug Deliv; 2011 Nov; 8(6):661-6. PubMed ID: 22313161
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models.
    Matsuzaki T; Takagi A; Furuta T; Ueno S; Kurita A; Nohara G; Kodaira H; Sawada S; Hashimoto S
    Oncol Rep; 2012 Jan; 27(1):189-97. PubMed ID: 21935577
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.