BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

658 related articles for article (PubMed ID: 25231868)

  • 1. Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks.
    Cannavo E; Cejka P
    Nature; 2014 Oct; 514(7520):122-5. PubMed ID: 25231868
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stepwise 5' DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble.
    Cannavo E; Reginato G; Cejka P
    Proc Natl Acad Sci U S A; 2019 Mar; 116(12):5505-5513. PubMed ID: 30819891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks.
    Shim EY; Chung WH; Nicolette ML; Zhang Y; Davis M; Zhu Z; Paull TT; Ira G; Lee SE
    EMBO J; 2010 Oct; 29(19):3370-80. PubMed ID: 20834227
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Processing of DNA double-stranded breaks and intermediates of recombination and repair by Saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins.
    Ghodke I; Muniyappa K
    J Biol Chem; 2013 Apr; 288(16):11273-86. PubMed ID: 23443654
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex.
    Lengsfeld BM; Rattray AJ; Bhaskara V; Ghirlando R; Paull TT
    Mol Cell; 2007 Nov; 28(4):638-51. PubMed ID: 18042458
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulatory control of DNA end resection by Sae2 phosphorylation.
    Cannavo E; Johnson D; Andres SN; Kissling VM; Reinert JK; Garcia V; Erie DA; Hess D; Thomä NH; Enchev RI; Peter M; Williams RS; Neale MJ; Cejka P
    Nat Commun; 2018 Oct; 9(1):4016. PubMed ID: 30275497
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles.
    Wang W; Daley JM; Kwon Y; Krasner DS; Sung P
    Genes Dev; 2017 Dec; 31(23-24):2331-2336. PubMed ID: 29321177
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Physiological protein blocks direct the Mre11-Rad50-Xrs2 and Sae2 nuclease complex to initiate DNA end resection.
    Reginato G; Cannavo E; Cejka P
    Genes Dev; 2017 Dec; 31(23-24):2325-2330. PubMed ID: 29321179
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mre11-Rad50-Xrs2 and Sae2 promote 5' strand resection of DNA double-strand breaks.
    Nicolette ML; Lee K; Guo Z; Rani M; Chow JM; Lee SE; Paull TT
    Nat Struct Mol Biol; 2010 Dec; 17(12):1478-85. PubMed ID: 21102445
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The MRX complex regulates Exo1 resection activity by altering DNA end structure.
    Gobbini E; Cassani C; Vertemara J; Wang W; Mambretti F; Casari E; Sung P; Tisi R; Zampella G; Longhese MP
    EMBO J; 2018 Aug; 37(16):. PubMed ID: 29925516
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection.
    Cannavo E; Cejka P; Kowalczykowski SC
    Proc Natl Acad Sci U S A; 2013 Apr; 110(18):E1661-8. PubMed ID: 23589858
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic Separation of Sae2 Nuclease Activity from Mre11 Nuclease Functions in Budding Yeast.
    Arora S; Deshpande RA; Budd M; Campbell J; Revere A; Zhang X; Schmidt KH; Paull TT
    Mol Cell Biol; 2017 Dec; 37(24):. PubMed ID: 28970327
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.
    Chen H; Donnianni RA; Handa N; Deng SK; Oh J; Timashev LA; Kowalczykowski SC; Symington LS
    Proc Natl Acad Sci U S A; 2015 Apr; 112(15):E1880-7. PubMed ID: 25831494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular insights into the activation of Mre11-Rad50 endonuclease activity by Sae2/CtIP.
    Nicolas Y; Bret H; Cannavo E; Acharya A; Cejka P; Borde V; Guerois R
    Mol Cell; 2024 Jun; 84(12):2223-2237.e4. PubMed ID: 38870937
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity.
    Ghosal G; Muniyappa K
    J Mol Biol; 2007 Sep; 372(4):864-882. PubMed ID: 17698079
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2.
    Mimitou EP; Symington LS
    EMBO J; 2010 Oct; 29(19):3358-69. PubMed ID: 20729809
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks.
    Mojumdar A; Sorenson K; Hohl M; Toulouze M; Lees-Miller SP; Dubrana K; Petrini JHJ; Cobb JA
    Cell Rep; 2019 Aug; 28(6):1564-1573.e3. PubMed ID: 31390569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex.
    Chen YJ; Chuang YC; Chuang CN; Cheng YH; Chang CR; Leng CH; Wang TF
    Nucleic Acids Res; 2016 Mar; 44(5):2199-213. PubMed ID: 26743002
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex.
    Oh J; Al-Zain A; Cannavo E; Cejka P; Symington LS
    Mol Cell; 2016 Oct; 64(2):405-415. PubMed ID: 27746018
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-function relationships of the Mre11 protein in the control of DNA end bridging and processing.
    Marsella A; Cassani C; Casari E; Tisi R; Longhese MP
    Curr Genet; 2019 Feb; 65(1):11-16. PubMed ID: 29922906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.