BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 25232057)

  • 1. Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.
    Wang J; Lu X; Sakk V; Klein CA; Rudolph KL
    Blood; 2014 Nov; 124(22):3237-40. PubMed ID: 25232057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Not merely quiescent: telomeres in quiescent HSCs.
    Nakamura-Ishizu A; Suda T
    Blood; 2014 Nov; 124(22):3179-80. PubMed ID: 25414434
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic stem cell function.
    Song Z; Zhang J; Ju Z; Rudolph KL
    Aging Cell; 2012 Jun; 11(3):449-55. PubMed ID: 22284665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses.
    Wang Y; Sharpless N; Chang S
    J Clin Invest; 2013 Oct; 123(10):4489-501. PubMed ID: 24091330
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Telomere dysfunction and cell cycle checkpoints in hematopoietic stem cell aging.
    Ju Z; Zhang J; Gao Y; Cheng T
    Int J Hematol; 2011 Jul; 94(1):33-43. PubMed ID: 21671044
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.
    Jones M; Osawa G; Regal JA; Weinberg DN; Taggart J; Kocak H; Friedman A; Ferguson DO; Keegan CE; Maillard I
    J Clin Invest; 2014 Jan; 124(1):353-66. PubMed ID: 24316971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells.
    Allsopp RC; Cheshier S; Weissman IL
    J Exp Med; 2001 Apr; 193(8):917-24. PubMed ID: 11304552
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hematopoietic stem cells lacking Ott1 display aspects associated with aging and are unable to maintain quiescence during proliferative stress.
    Xiao N; Jani K; Morgan K; Okabe R; Cullen DE; Jesneck JL; Raffel GD
    Blood; 2012 May; 119(21):4898-907. PubMed ID: 22490678
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation.
    Allsopp RC; Morin GB; DePinho R; Harley CB; Weissman IL
    Blood; 2003 Jul; 102(2):517-20. PubMed ID: 12663456
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hematopoiesis under telomere attrition at the single-cell resolution.
    Thongon N; Ma F; Santoni A; Marchesini M; Fiorini E; Rose A; Adema V; Ganan-Gomez I; Groarke EM; Gutierrez-Rodrigues F; Chen S; Lockyer P; Schneider S; Bueso-Ramos C; Montalban-Bravo G; Class CA; Soltysiak KA; Pellegrini M; Sahin E; Bertuch AA; DiNardo CD; Garcia-Manero G; Young NS; Dwyer K; Colla S
    Nat Commun; 2021 Nov; 12(1):6850. PubMed ID: 34824242
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival.
    Wingert S; Thalheimer FB; Haetscher N; Rehage M; Schroeder T; Rieger MA
    Stem Cells; 2016 Mar; 34(3):699-710. PubMed ID: 26731607
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment.
    Gu BW; Fan JM; Bessler M; Mason PJ
    Aging Cell; 2011 Apr; 10(2):338-48. PubMed ID: 21241452
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Determining the influence of telomere dysfunction and DNA damage on stem and progenitor cell aging: what markers can we use?
    Nalapareddy K; Jiang H; Guachalla Gutierrez LM; Rudolph KL
    Exp Gerontol; 2008 Nov; 43(11):998-1004. PubMed ID: 18817864
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence.
    Luo Y; Li L; Zou P; Wang J; Shao L; Zhou D; Liu L
    Transplantation; 2014 Jan; 97(1):20-9. PubMed ID: 24092377
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells.
    Bai L; Lyu Y; Shi G; Li K; Huang Y; Ma Y; Cong YS; Zhang L; Qin C
    Aging (Albany NY); 2020 Oct; 12(20):20152-20162. PubMed ID: 33087586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypercholesterolemia induces oxidant stress that accelerates the ageing of hematopoietic stem cells.
    Tie G; Messina KE; Yan J; Messina JA; Messina LM
    J Am Heart Assoc; 2014 Jan; 3(1):e000241. PubMed ID: 24470519
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment.
    Ju Z; Jiang H; Jaworski M; Rathinam C; Gompf A; Klein C; Trumpp A; Rudolph KL
    Nat Med; 2007 Jun; 13(6):742-7. PubMed ID: 17486088
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inflammatory ROS promote and cooperate with the Fanconi anemia mutation for hematopoietic senescence.
    Zhang X; Sejas DP; Qiu Y; Williams DA; Pang Q
    J Cell Sci; 2007 May; 120(Pt 9):1572-83. PubMed ID: 17405815
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CHK2-independent induction of telomere dysfunction checkpoints in stem and progenitor cells.
    Nalapareddy K; Choudhury AR; Gompf A; Ju Z; Ravipati S; Leucht T; Lechel A; Rudolph KL
    EMBO Rep; 2010 Aug; 11(8):619-25. PubMed ID: 20577265
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis.
    Fali T; Fabre-Mersseman V; Yamamoto T; Bayard C; Papagno L; Fastenackels S; Zoorab R; Koup RA; Boddaert J; Sauce D; Appay V
    JCI Insight; 2018 Jul; 3(13):. PubMed ID: 29997288
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.