BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 25237860)

  • 1. Screening technologies for small molecule discovery: the state of the art.
    Janzen WP
    Chem Biol; 2014 Sep; 21(9):1162-70. PubMed ID: 25237860
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-throughput screening for modulators of protein-protein interactions: use of photonic crystal biosensors and complementary technologies.
    Heeres JT; Hergenrother PJ
    Chem Soc Rev; 2011 Aug; 40(8):4398-410. PubMed ID: 21140010
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Affinity-based screening techniques: their impact and benefit to increase the number of high quality leads.
    Bergsdorf C; Ottl J
    Expert Opin Drug Discov; 2010 Nov; 5(11):1095-107. PubMed ID: 22827747
    [TBL] [Abstract][Full Text] [Related]  

  • 4. To screen or not to screen: an impassioned plea for smarter chemical libraries to improve drug lead finding.
    Lushington G; Chaguturu R
    Future Med Chem; 2014 Apr; 6(5):497-502. PubMed ID: 24649953
    [No Abstract]   [Full Text] [Related]  

  • 5. Novel trends in high-throughput screening.
    Mayr LM; Bojanic D
    Curr Opin Pharmacol; 2009 Oct; 9(5):580-8. PubMed ID: 19775937
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A dual-readout F2 assay that combines fluorescence resonance energy transfer and fluorescence polarization for monitoring bimolecular interactions.
    Du Y; Nikolovska-Coleska Z; Qui M; Li L; Lewis I; Dingledine R; Stuckey JA; Krajewski K; Roller PP; Wang S; Fu H
    Assay Drug Dev Technol; 2011 Aug; 9(4):382-93. PubMed ID: 21395401
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Review article: high-throughput affinity-based technologies for small-molecule drug discovery.
    Zhu Z; Cuozzo J
    J Biomol Screen; 2009 Dec; 14(10):1157-64. PubMed ID: 19822881
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Big pharma screening collections: more of the same or unique libraries? The AstraZeneca-Bayer Pharma AG case.
    Kogej T; Blomberg N; Greasley PJ; Mundt S; Vainio MJ; Schamberger J; Schmidt G; Hüser J
    Drug Discov Today; 2013 Oct; 18(19-20):1014-24. PubMed ID: 23127858
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biophysical methods in drug discovery from small molecule to pharmaceutical.
    Holdgate G; Geschwindner S; Breeze A; Davies G; Colclough N; Temesi D; Ward L
    Methods Mol Biol; 2013; 1008():327-55. PubMed ID: 23729258
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent trends and observations in the design of high-quality screening collections.
    Renner S; Popov M; Schuffenhauer A; Roth HJ; Breitenstein W; Marzinzik A; Lewis I; Krastel P; Nigsch F; Jenkins J; Jacoby E
    Future Med Chem; 2011 Apr; 3(6):751-66. PubMed ID: 21554080
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small-molecule procaspase activators identified using fluorescence polarization.
    Vickers CJ; González-Páez GE; Umotoy JC; Cayanan-Garrett C; Brown SJ; Wolan DW
    Chembiochem; 2013 Aug; 14(12):1419-22. PubMed ID: 23836614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combining biophysical screening and X-ray crystallography for fragment-based drug discovery.
    Hennig M; Ruf A; Huber W
    Top Curr Chem; 2012; 317():115-43. PubMed ID: 21837555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Screening Ligands by X-ray crystallography.
    Davies DR
    Methods Mol Biol; 2014; 1140():315-23. PubMed ID: 24590727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Editorial overview: Next generation therapeutics: Creating and exploiting the chemistry of large numbers.
    Scheuermann J; Neri D
    Curr Opin Chem Biol; 2015 Jun; 26():iv-v. PubMed ID: 25890575
    [No Abstract]   [Full Text] [Related]  

  • 15. Diversity-oriented fluorescence library approaches for probe discovery and development.
    Vendrell M; Lee JS; Chang YT
    Curr Opin Chem Biol; 2010 Jun; 14(3):383-9. PubMed ID: 20227904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A high-throughput, homogeneous, fluorescence resonance energy transfer-based assay for phospho-N-acetylmuramoyl-pentapeptide translocase (MraY).
    Shapiro AB; Jahić H; Gao N; Hajec L; Rivin O
    J Biomol Screen; 2012 Jun; 17(5):662-72. PubMed ID: 22337656
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fragment-based lead discovery and design.
    Joseph-McCarthy D; Campbell AJ; Kern G; Moustakas D
    J Chem Inf Model; 2014 Mar; 54(3):693-704. PubMed ID: 24490951
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of a high-throughput fluorescence polarization DNA cleavage assay for the identification of FEN1 inhibitors.
    McWhirter C; Tonge M; Plant H; Hardern I; Nissink W; Durant ST
    J Biomol Screen; 2013 Jun; 18(5):567-75. PubMed ID: 23427045
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Contribution of Automated Technologies to Ion Channel Drug Discovery.
    Picones A; Loza-Huerta A; Segura-Chama P; Lara-Figueroa CO
    Adv Protein Chem Struct Biol; 2016; 104():357-378. PubMed ID: 27038379
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA-encoded chemical libraries: a tool for drug discovery and for chemical biology.
    Scheuermann J; Neri D
    Chembiochem; 2010 May; 11(7):931-7. PubMed ID: 20391457
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 11.