98 related articles for article (PubMed ID: 25238284)
1. Identification of a novel aminotetralin class of HDAC6 and HDAC8 selective inhibitors.
Tang G; Wong JC; Zhang W; Wang Z; Zhang N; Peng Z; Zhang Z; Rong Y; Li S; Zhang M; Yu L; Feng T; Zhang X; Wu X; Wu JZ; Chen L
J Med Chem; 2014 Oct; 57(19):8026-34. PubMed ID: 25238284
[TBL] [Abstract][Full Text] [Related]
2. Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
Morgen M; Steimbach RR; Géraldy M; Hellweg L; Sehr P; Ridinger J; Witt O; Oehme I; Herbst-Gervasoni CJ; Osko JD; Porter NJ; Christianson DW; Gunkel N; Miller AK
ChemMedChem; 2020 Jul; 15(13):1163-1174. PubMed ID: 32348628
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and structure-activity relationship of 3-hydroxypyridine-2-thione-based histone deacetylase inhibitors.
Sodji QH; Patil V; Kornacki JR; Mrksich M; Oyelere AK
J Med Chem; 2013 Dec; 56(24):9969-81. PubMed ID: 24304348
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel benzimidazole derivatives as potent HDACs inhibitors against leukemia with (Thio)Hydantoin as zinc-binding moiety: Design, synthesis, enzyme inhibition, and cellular mechanistic study.
Abdulwahab HG; Mansour RE; Farghaly TA; El-Sehrawi HM
Bioorg Chem; 2024 May; 146():107284. PubMed ID: 38493640
[TBL] [Abstract][Full Text] [Related]
5. Identification of a Histone Deacetylase 8 Inhibitor through Drug Screenings Based on Machine Learning.
Nurani A; Yamashita Y; Taki Y; Takada Y; Itoh Y; Suzuki T
Chem Pharm Bull (Tokyo); 2024; 72(2):173-178. PubMed ID: 38296560
[TBL] [Abstract][Full Text] [Related]
6. Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation.
Upadhyay N; Tilekar K; Jänsch N; Schweipert M; Hess JD; Henze Macias L; Mrowka P; Aguilera RJ; Choe JY; Meyer-Almes FJ; Ramaa CS
Bioorg Chem; 2020 Jul; 100():103934. PubMed ID: 32446120
[TBL] [Abstract][Full Text] [Related]
7. Discovery of histone deacetylase 8 selective inhibitors.
Tang W; Luo T; Greenberg EF; Bradner JE; Schreiber SL
Bioorg Med Chem Lett; 2011 May; 21(9):2601-5. PubMed ID: 21334896
[TBL] [Abstract][Full Text] [Related]
8. Discovery of HDAC6, HDAC8, and 6/8 Inhibitors and Development of Cell-Based Drug Screening Models for the Treatment of TGF-β-Induced Idiopathic Pulmonary Fibrosis.
Yu WC; Yeh TY; Ye CH; Chong PCT; Ho YH; So DK; Yap KY; Peng GR; Shao CH; Jagtap AD; Chern JW; Lin CS; Lin SP; Lin SL; Yu SH; Yu CW
J Med Chem; 2023 Aug; 66(15):10528-10557. PubMed ID: 37463500
[TBL] [Abstract][Full Text] [Related]
9. An unbiased approach to identify endogenous substrates of "histone" deacetylase 8.
Olson DE; Udeshi ND; Wolfson NA; Pitcairn CA; Sullivan ED; Jaffe JD; Svinkina T; Natoli T; Lu X; Paulk J; McCarren P; Wagner FF; Barker D; Howe E; Lazzaro F; Gale JP; Zhang YL; Subramanian A; Fierke CA; Carr SA; Holson EB
ACS Chem Biol; 2014 Oct; 9(10):2210-6. PubMed ID: 25089360
[TBL] [Abstract][Full Text] [Related]
10. HDAC8 as an emerging target in drug discovery with special emphasis on medicinal chemistry.
Rajaraman S; Balakrishnan R; Deshmukh D; Ganorkar A; Biswas S; Pulya S; Ghosh B
Future Med Chem; 2023 May; 15(10):885-908. PubMed ID: 37227732
[TBL] [Abstract][Full Text] [Related]
11. Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation.
Itoh Y; Zhan P; Tojo T; Jaikhan P; Ota Y; Suzuki M; Li Y; Hui Z; Moriyama Y; Takada Y; Yamashita Y; Oba M; Uchida S; Masuda M; Ito S; Sowa Y; Sakai T; Suzuki T
J Med Chem; 2023 Nov; 66(22):15171-15188. PubMed ID: 37847303
[TBL] [Abstract][Full Text] [Related]
12. Discovery of (S)-N
Zhang Y; Gao J; Wu J; Liu S; Zhang X; Lv X
Bioorg Med Chem Lett; 2023 Oct; 94():129462. PubMed ID: 37652098
[TBL] [Abstract][Full Text] [Related]
13. Design, Synthesis, and Antiproliferative Activity of Selective Histone Deacetylases 6 Inhibitors Containing a Tetrahydropyridopyrimidine Scaffold.
Wang B; Liu Y; Zhang L; Wang Y; Li Z; Chen X
Molecules; 2023 Oct; 28(21):. PubMed ID: 37959743
[TBL] [Abstract][Full Text] [Related]
14. Histone-deacetylase 8 drives the immune response and the growth of glioma.
Mormino A; Cocozza G; Fontemaggi G; Valente S; Esposito V; Santoro A; Bernardini G; Santoni A; Fazi F; Mai A; Limatola C; Garofalo S
Glia; 2021 Nov; 69(11):2682-2698. PubMed ID: 34310727
[TBL] [Abstract][Full Text] [Related]
15. Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors.
Keeley AB; Kopranovic A; Di Lorenzo V; Ábrányi-Balogh P; Jänsch N; Lai LN; Petri L; Orgován Z; Pölöske D; Orlova A; Németh AG; Desczyk C; Imre T; Bajusz D; Moriggl R; Meyer-Almes FJ; Keserü GM
J Med Chem; 2024 Jan; 67(1):572-585. PubMed ID: 38113354
[TBL] [Abstract][Full Text] [Related]
16. Corroborating evidence for aberrant expression of histone deacetylase 8 in endometriosis.
Zheng H; Liu X; Guo SW
Reprod Med Biol; 2023; 22(1):e12527. PubMed ID: 37476367
[TBL] [Abstract][Full Text] [Related]
17. Integrated molecular modeling and dynamics approaches revealed the mechanism of selective inhibition of HDAC6/8.
Li Y; Liu S; Xu X; Xu J; Yang L; Hu L
J Biomol Struct Dyn; 2023 Oct; ():1-14. PubMed ID: 37870047
[TBL] [Abstract][Full Text] [Related]
18. Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor.
Porter NJ; Shen S; Barinka C; Kozikowski AP; Christianson DW
ACS Med Chem Lett; 2018 Dec; 9(12):1301-1305. PubMed ID: 30613344
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d]pyrimidine-based hydroxamic acid derivatives as novel histone deacetylase inhibitors.
Yang W; Li L; Ji X; Wu X; Su M; Sheng L; Zang Y; Li J; Liu H
Bioorg Med Chem; 2014 Nov; 22(21):6146-55. PubMed ID: 25261927
[TBL] [Abstract][Full Text] [Related]
20. Design and synthesis of orally bioavailable aminopyrrolidinone histone deacetylase 6 inhibitors.
Lin X; Chen W; Qiu Z; Guo L; Zhu W; Li W; Wang Z; Zhang W; Zhang Z; Rong Y; Zhang M; Yu L; Zhong S; Zhao R; Wu X; Wong JC; Tang G
J Med Chem; 2015 Mar; 58(6):2809-20. PubMed ID: 25734520
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
